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Results for “Tyrosine Kinase Inhibitor”

894 trials

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Showing 20 of 894 results

Early research (Phase 1)Ended earlyNCT02292225
What this trial is testing

Duvelisib With Obinutuzumab in Patients With CLL/SLL Previously Treated With a BTKi (SYNCHRONY)

Who this might be right for
Lymphocytic Leukemia, ChronicLymphoma, Small Lymphocytic
SecuraBio 3
Large-scale testing (Phase 3)UnknownNCT06140186
What this trial is testing

Efficacy and Safety of Timolol for TKI Induced Paronychia

Who this might be right for
Paronychia
Queen Mary Hospital, Hong Kong 40
Early research (Phase 1)Study completedNCT04564040
What this trial is testing

A Study in Healthy Subjects to Assess Bioavailability (Proportion of a Drug Which Enters the Circulation to Have an Active Effect) of Acalabrutinib Tablet and Protonpump Inhibitor Effect (Members of a Class of Medications That Inhibits in Gastric Acid Production) for Rabeprazole

Who this might be right for
Mantle Cell LymphomaCOVID-19
AstraZeneca 20
Testing effectiveness (Phase 2)Active Not RecruitingNCT03516279
What this trial is testing

Pembrolizumab and Dasatinib, Imatinib Mesylate, or Nilotinib in Treating Patients With Chronic Myeloid Leukemia and Persistently Detectable Minimal Residual Disease

Who this might be right for
Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 PositiveMinimal Residual Disease
ECOG-ACRIN Cancer Research Group 40
Not applicableStudy completedNCT02592356
What this trial is testing

Effect of Cabozantinib S-Malate or Lenvatinib Mesylate on Weight and Body Composition in Patients With Metastatic Endocrine Cancer

Who this might be right for
Differentiated Thyroid Gland CarcinomaMalignant Adrenal Gland PheochromocytomaMalignant Paraganglioma+1 more
M.D. Anderson Cancer Center 23
Early research (Phase 1)Study completedNCT02451553
What this trial is testing

Afatinib Dimaleate and Capecitabine in Treating Patients With Advanced Refractory Solid Tumors, Pancreatic Cancer or Biliary Cancer

Who this might be right for
Advanced Malignant Solid NeoplasmBile Duct CarcinomaRecurrent Malignant Solid Neoplasm+4 more
University of Washington 41
Testing effectiveness (Phase 2)Study completedNCT04193553
What this trial is testing

Multicentre Placebo-controlled Double-blinded Phase II Study of Lenvatinib Efficacy in Patients With Locally Advanced or Metastatic GIST (Gastrointestinal Stromal Tumor) After Imatinib/Sunitinib Failure

Who this might be right for
Gastro Intestinal Stromal Tumour
Centre Leon Berard 77
Large-scale testing (Phase 3)Study completedNCT02864251
What this trial is testing

Nivolumab + Chemotherapy or Nivolumab + Ipilimumab Versus Chemotherapy in Non-Small Cell Lung Cancer (NSCLC) Participants With Epidermal Growth Factor Receptor (EGFR) Mutation Who Failed 1L or 2L EGFR Tyrosine Kinase Inhibitor (TKI) Therapy

Who this might be right for
Non-Small-Cell Lung Carcinoma
Bristol-Myers Squibb 367
Large-scale testing (Phase 3)Study completedNCT04246177
What this trial is testing

Safety and Efficacy of Lenvatinib (E7080/MK-7902) With Pembrolizumab (MK-3475) in Combination With Transarterial Chemoembolization (TACE) in Participants With Incurable/Non-metastatic Hepatocellular Carcinoma (MK-7902-012/E7080-G000-318/LEAP-012)

Who this might be right for
Carcinoma, Hepatocellular
Merck Sharp & Dohme LLC 479
Testing effectiveness (Phase 2)Study completedNCT01034631
What this trial is testing

BNC105P in Combination With Everolimus/Following Everolimus For Progressive Metastatic Clear Cell Renal Cell Carcinoma

Who this might be right for
Renal Cell Carcinoma
Hoosier Cancer Research Network 154
Large-scale testing (Phase 3)Ended earlyNCT01599754
What this trial is testing

Adjuvant Axitinib Therapy of Renal Cell Cancer in High Risk Patients

Who this might be right for
Clear Cell Renal Carcinoma
SFJ Pharma Ltd. II 724
Testing effectiveness (Phase 2)Study completedNCT02169180
What this trial is testing

Study of the Bruton's Tyrosine Kinase (BTK) Inhibitor Ibrutinib in Participants With Relapsed or Refractory Mantle Cell Lymphoma

Who this might be right for
Lymphoma, Mantle-cell
Janssen Pharmaceutical K.K. 16
Testing effectiveness (Phase 2)Study completedNCT02195869
What this trial is testing

Study of the Bruton's Tyrosine Kinase Inhibitor in Subjects With Chronic Graft Versus Host Disease

Who this might be right for
Graft Versus Host Disease
Pharmacyclics LLC. 45
Early research (Phase 1)Looking for participantsNCT05131022
What this trial is testing

NX-5948 in Adults With Relapsed/Refractory B-cell Malignancies

Who this might be right for
Chronic Lymphocytic Leukemia (CLL)Small Lymphocytic Lymphoma (SLL)Diffuse Large B Cell Lymphoma (DLBCL)+6 more
Nurix Therapeutics, Inc. 572
Not applicableStudy completedNCT01486251
What this trial is testing

Assessment of Tumor Vascular Effects of Axitinib With Dynamic Ultrasonography in Patients With Metastatic Colorectal Cancer

Who this might be right for
Colorectal Carcinoma
Gustave Roussy, Cancer Campus, Grand Paris 27
Early research (Phase 1)Study completedNCT02727283
What this trial is testing

A Phase 1, Randomized, Placebo-Controlled, Ascending Cohort, Dose Escalation Study in Normal Healthy Volunteers

Who this might be right for
Irritable Bowel Syndrome
GlaxoSmithKline 16
Large-scale testing (Phase 3)Temporarily pausedNCT05441488
What this trial is testing

Masitinib in the Treatment of Patients With Primary Progressive or Non-active Secondary Progressive Multiple Sclerosis

Who this might be right for
Progressive Multiple Sclerosis
AB Science 800
Testing effectiveness (Phase 2)Looking for participantsNCT04925479
What this trial is testing

Study to Determine the Dose and Safety of Asciminib in Pediatric Patients With Chronic Myeloid Leukemia

Who this might be right for
Myeloid Leukemia, Philadelphia Positive
Novartis Pharmaceuticals 34
Testing effectiveness (Phase 2)Study completedNCT00045487
What this trial is testing

Erlotinib in Treating Patients With Advanced Kidney Cancer

Who this might be right for
Kidney Cancer
The University of Texas Health Science Center at San Antonio 41
Testing effectiveness (Phase 2)Study completedNCT03889639
What this trial is testing

Dose-finding Study for SAR442168 in Relapsing Multiple Sclerosis

Who this might be right for
Relapsing Multiple Sclerosis
Sanofi 130
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