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Results for “Tyrosine Kinase Inhibitor”

909 trials

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Showing 20 of 909 results

Not applicableLooking for participantsNCT04151342
What this trial is testing

CAnadian CAncers With Rare Molecular Alterations (CARMA) - Basket Real-world Observational Study (BROS)

Who this might be right for
CancerMalignancies MultipleMalignant Solid Tumor+7 more
University Health Network, Toronto 5,500
Testing effectiveness (Phase 2)Enrolling By InvitationNCT07393373
What this trial is testing

Open-Label, Long-Term, Extension Study of Infigratinib in Children With Hypochondroplasia

Who this might be right for
Hypochondroplasia
QED Therapeutics, a BridgeBio company 135
Early research (Phase 1)Ended earlyNCT02342353
What this trial is testing

Pacritinib in Patients With Endothelial Growth Factor (EGFR) Mutant Non-small Cell Lung Cancer (NSCLC) After EGFR Tyrosine Kinase Inhibitor (TKI)

Who this might be right for
Non-Small Cell Lung CancerNonsmall Cell Lung CancerCarcinoma, Non-Small-Cell Lung
Washington University School of Medicine 8
Early research (Phase 1)Study completedNCT04564040
What this trial is testing

A Study in Healthy Subjects to Assess Bioavailability (Proportion of a Drug Which Enters the Circulation to Have an Active Effect) of Acalabrutinib Tablet and Protonpump Inhibitor Effect (Members of a Class of Medications That Inhibits in Gastric Acid Production) for Rabeprazole

Who this might be right for
Mantle Cell LymphomaCOVID-19
AstraZeneca 20
Testing effectiveness (Phase 2)UnknownNCT03647956
What this trial is testing

Atezolizumab in Combination With Bevacizumab, Carboplatin and Pemetrexed for EGFR-mutant Metastatic NSCLC Patients After Failure of EGFR Tyrosine Kinase Inhibitors

Who this might be right for
NSCLC Stage IIIBNSCLC Stage IVEGFR Activating Mutation
The University of Hong Kong 40
Testing effectiveness (Phase 2)Study completedNCT02824029
What this trial is testing

Ibrutinib in Treating Patients With Relapsed or Refractory Classical Hodgkin Lymphoma

Who this might be right for
Classical Hodgkin LymphomaRecurrent Hodgkin LymphomaRefractory Hodgkin Lymphoma
Barbara Ann Karmanos Cancer Institute 28
Testing effectiveness (Phase 2)Study completedNCT05383209
What this trial is testing

Study of EYP-1901 in Patients With Nonproliferative Diabetic Retinopathy (NPDR)

Who this might be right for
Nonproliferative Diabetic Retinopathy
EyePoint Pharmaceuticals, Inc. 77
Large-scale testing (Phase 3)Looking for participantsNCT07277231
What this trial is testing

Investigate Sonrotoclax (BGB-11417) Plus Zanubrutinib (BGB-3111) Compared With Venetoclax Plus Acalabrutinib in Adults With Previously Untreated Chronic Lymphocytic Leukemia

Who this might be right for
Chronic Lymphocytic Leukemia
BeOne Medicines 500
Testing effectiveness (Phase 2)UnknownNCT05176665
What this trial is testing

EMB-01 in Patients With Advanced/Metastatic Gastrointestinal Cancers

Who this might be right for
NeoplasmsNeoplasm MetastasisMetastatic Gastrointestinal Carcinoid Tumor
Shanghai EpimAb Biotherapeutics Co., Ltd. 152
Early research (Phase 1)Study completedNCT02556892
What this trial is testing

Bruton's Tyrosine Kinase (BTK) Inhibitor Ibrutinib in Participants With Treatment-naive Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

Who this might be right for
Lymphocytic Leukemia
Janssen Pharmaceutical K.K. 8
Testing effectiveness (Phase 2)Study completedNCT01283945
What this trial is testing

Study of Oral Lucitanib (E-3810), a Dual VEGFR-FGFR Tyrosine Kinase Inhibitor, in Patients With Solid Tumors

Who this might be right for
Solid Tumors
Institut de Recherches Internationales Servier 134
Not applicableStudy completedNCT03885830
What this trial is testing

Precision Dosing of Tyrosine Kinase Inhibitors in CML Patients

Who this might be right for
CML, Chronic PhaseCML (Chronic Myelogenous LeukemiaCML - Philadelphia Chromosome+2 more
UNC Lineberger Comprehensive Cancer Center 45
Not applicableUnknownNCT04967495
What this trial is testing

TACE Plus Multikinase Inhibitor and I-125 Seeds Brachytherapy for HCC With Branch PVTT

Who this might be right for
Hepatocellular Carcinoma Non-resectable
Second Affiliated Hospital of Guangzhou Medical University 171
Testing effectiveness (Phase 2)Study completedNCT03088878
What this trial is testing

Cirmtuzumab and Ibrutinib in Patients With B-Cell Lymphoid Malignancies

Who this might be right for
B-cell Chronic Lymphocytic LeukemiaSmall Lymphocytic LymphomaMantle Cell Lymphoma+1 more
Oncternal Therapeutics, Inc 95
Early research (Phase 1)Study completedNCT03215511
What this trial is testing

Test the Safety of the Investigational Drug Selitrectinib in Children and Adults That May Treat Cancer

Who this might be right for
Solid Tumors Harboring NTRK Fusion
Bayer 81
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06563934
What this trial is testing

Gut Microbiota in Liver Cancer (Treated With TKIs In Combination With ICIs)

Who this might be right for
Liver Cancer
Xu Yong, MD 70
Large-scale testing (Phase 3)Ended earlyNCT02893332
What this trial is testing

Stereotactic Body Radiation Therapy (SBRT) in Newly Diagnosed Advanced Staged Lung Adenocarcinoma (Sindas)

Who this might be right for
Stage IV EGFR Mutated Non-Small Cell Lung Cancer
Sichuan Provincial People's Hospital 200
Not applicableStudy completedNCT07449065
What this trial is testing

CECT Features of MVI Predict Response to TACE Plus TKI in Intermediate-stage HCC

Who this might be right for
Hepatocellular Carcinoma (HCC)Transarterial ChemoembolizationMicrovascular Invasion (MVI)+1 more
First Affiliated Hospital, Sun Yat-Sen University 324
Not applicableUnknownNCT02172365
What this trial is testing

Allogeneic SCT for CML, TKI Failure After TKI Failure

Who this might be right for
Chronic Myeloid Leukemia
University Health Network, Toronto 350
Not applicableUnknownNCT01700699
What this trial is testing

Impact of BRAFV600E Intratumor Heterogeneity in Thyroid Cancer Treated With Tyrosine Kinase Inhibitors

Who this might be right for
Differentiated Thyroid Cancer
University of Salerno 50
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