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Results for “Tyrosine Kinase Inhibitor”

890 trials

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Showing 20 of 890 results

Testing effectiveness (Phase 2)Study completedNCT03145064
What this trial is testing

Study of BTK Inhibitor Zanubrutinib in Participants With Relapsed/Refractory Non-GCB Type Diffuse Large B Cell Lymphoma

Who this might be right for
Diffuse Large B-cell Lymphoma
BeiGene 41
Large-scale testing (Phase 3)Study completedNCT00116935
What this trial is testing

Study Comparing 12 Months Versus 36 Months of Imatinib in the Treatment of Gastrointestinal Stromal Tumor (GIST)

Who this might be right for
Sarcoma
Scandinavian Sarcoma Group 400
Early research (Phase 1)Study completedNCT01061411
What this trial is testing

Dalteparin and Sunitinib Malate as First-Line Therapy in Treating Patients With Kidney Cancer That is Metastatic or Cannot Be Removed by Surgery

Who this might be right for
Clear Cell Sarcoma of the KidneyRecurrent Renal Cell CarcinomaStage III Renal Cell Cancer+1 more
Roswell Park Cancer Institute 16
Testing effectiveness (Phase 2)Study completedNCT03037385
What this trial is testing

Phase 1/2 Study of the Highly-selective RET Inhibitor, Pralsetinib (BLU-667), in Participants With Thyroid Cancer, Non-Small Cell Lung Cancer, and Other Advanced Solid Tumors

Who this might be right for
RET-altered Non Small Cell Lung CancerMedullary Thyroid CancerRET-altered Papillary Thyroid Cancer+37 more
Hoffmann-La Roche 590
Testing effectiveness (Phase 2)Study completedNCT03544814
What this trial is testing

EGFR-TKI Combined With Concurrent or Sequential Chemotherapy for Patients of Gradual Progression

Who this might be right for
Lung AdenocarcinomaEGFR Activating Mutation
Shanghai Chest Hospital 99
Testing effectiveness (Phase 2)Study completedNCT00074867
What this trial is testing

Study Of An Oral Tyrosine Kinase Inhibitor Of VEGFR-2 To Treat Small-Volume Ovarian, Peritoneal, Fallopian Tube Cancer

Who this might be right for
Ovarian NeoplasmsPeritoneal NeoplasmsFallopian Tube Neoplasms
Pfizer 29
Testing effectiveness (Phase 2)UnknownNCT03994393
What this trial is testing

Non Small Cell Lung Cancer Trial of Durvalumab and Tremelimumab in Advanced Epidermal Growth Factor Receptor (EGFR) Mutant Disease.

Who this might be right for
EGFR Mutant Advanced Non Small Cell Lung Cancer
University of Sydney 100
Large-scale testing (Phase 3)Active Not RecruitingNCT06223958
What this trial is testing

Study to Evaluate the Efficacy and Safety of Intravitreal OTX-TKI (Ocular Therapeutix) (Axitinib Implant) in Subjects With Neovascular Age-Related Macular Degeneration

Who this might be right for
Neovascular Age-Related Macular Degeneration
Ocular Therapeutix, Inc. 344
Not applicableWithdrawnNCT04219111
What this trial is testing

Gene Expression Profiles in CML Non-responders

Who this might be right for
Gene Expression Profiles in CML Non-responders
Sheffield Children's NHS Foundation Trust
Not applicableActive Not RecruitingNCT06632106
What this trial is testing

HAIC in Combination with Immune Checkpoint Inhibitors and Tyrosine Kinase Inhibitors for Advanced HCC

Who this might be right for
Hepatic Arterial Infusion ChemotherapyTyrosine Kinase InhibitorImmune Checkpoint Inhibitors+1 more
First Hospital of China Medical University 97
Not applicableUnknownNCT05231863
What this trial is testing

Tyrosine Kinase Inhibitors (TKIs) in Trastuzumab Emtansine (T-DM1) Resistant HER2-positive Metastatic Breast Cancer: A Real-world Study

Who this might be right for
Breast Cancer
The First Affiliated Hospital with Nanjing Medical University 100
Early research (Phase 1)Study completedNCT02211014
What this trial is testing

An Open-Label, Phase 1b Study of Acalabrutinib With and Without Dexamethasone in Subjects With Multiple Myeloma

Who this might be right for
Multiple Myeloma (MM)
Acerta Pharma BV 27
Early research (Phase 1)Study completedNCT01703481
What this trial is testing

Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of JNJ-42756493 in Adult Participants With Advanced or Refractory Solid Tumors or Lymphoma

Who this might be right for
Tumor or Lymphoma
Janssen Research & Development, LLC 188
Large-scale testing (Phase 3)Active Not RecruitingNCT04246177
What this trial is testing

Safety and Efficacy of Lenvatinib (E7080/MK-7902) With Pembrolizumab (MK-3475) in Combination With Transarterial Chemoembolization (TACE) in Participants With Incurable/Non-metastatic Hepatocellular Carcinoma (MK-7902-012/E7080-G000-318/LEAP-012)

Who this might be right for
Carcinoma, Hepatocellular
Merck Sharp & Dohme LLC 480
Not applicableUnknownNCT05259228
What this trial is testing

Therapeutic Drug Monitoring of Tyrosine Kinase Inhibitor in Patients With Chronic Myeloid Leukemia

Who this might be right for
Tyrosine Kinase InhibitorPharmacokineticsTherapeutic Drug Monitoring
National Taiwan University Hospital 40
Early research (Phase 1)Study completedNCT00040781
What this trial is testing

Gefitinib in Treating Children With Refractory Solid Tumors

Who this might be right for
Unspecified Childhood Solid Tumor, Protocol Specific
National Cancer Institute (NCI) 45
Early research (Phase 1)Study completedNCT00681967
What this trial is testing

Postoperative Radiotherapy Plus Iressa or Radiotherapy Plus Cisplatin and Iressa for Advanced Head & Neck Cancer

Who this might be right for
Head and Neck Cancer
AstraZeneca 30
Early research (Phase 1)Study completedNCT01469052
What this trial is testing

First In Human, Phase 1 Study of AG013736 In Patients With Solid Tumors

Who this might be right for
Advanced Solid Tumors
Pfizer 36
Testing effectiveness (Phase 2)Study completedNCT03088878
What this trial is testing

Cirmtuzumab and Ibrutinib in Patients With B-Cell Lymphoid Malignancies

Who this might be right for
B-cell Chronic Lymphocytic LeukemiaSmall Lymphocytic LymphomaMantle Cell Lymphoma+1 more
Oncternal Therapeutics, Inc 95
Testing effectiveness (Phase 2)Study completedNCT00615758
What this trial is testing

Erlotinib as 1st Line Treatment in NSCLC Stage IIIB/IV

Who this might be right for
Non Small Cell Lung Cancer
Hellenic Oncology Research Group 50
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