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Results for “Tyrosine Kinase Inhibitors”

829 trials

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Showing 20 of 829 results

Not applicableStudy completedNCT01098500
What this trial is testing

Liver Function Test (LFT) Elevations in Cancer Patients and Users of Tyrosine Kinase Inhibitor (TKI) Drugs

Who this might be right for
Cancer
GlaxoSmithKline 3,800
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07557121
What this trial is testing

Safety and Efficacy of AIV007 Periocular Injection in Patients With Neovascular Age-Related Macular Degeneration

Who this might be right for
Neovascular (Wet) Age-Related Macular Degeneration
AiViva BioPharma, Inc. 35
Testing effectiveness (Phase 2)UnknownNCT02906163
What this trial is testing

First Line Bio-immunotherapy With Thymosin Alpha 1 in Patients With Sensitizing EGFR Mutation Positive Non Small Cell Lung Cancer Who Are Taking Standard of Care Therapy

Who this might be right for
EGFR Mutation Positive Non Small Cell Lung Cancer
SciClone Pharmaceuticals 188
Not applicableLooking for participantsNCT05713994
What this trial is testing

Combined HAIC, TKI/Anti-VEGF and ICIs as Conversion Therapy for Unresectable Hepatocellular Carcinoma

Who this might be right for
Hepatocellular Carcinoma Non-resectable
Ze-yang Ding, MD 300
Early research (Phase 1)Looking for participantsNCT06705686
What this trial is testing

Novel ACK1 Inhibitor (R)-9b in Patients With Prostate Cancer

Who this might be right for
Metastatic Castration-resistant Prostate Cancer (CRPC)Metastatic Castration-resistant Prostate Carcinoma
TechnoGenesys, Inc. 40
Large-scale testing (Phase 3)UnknownNCT03564470
What this trial is testing

Precision Diagnosis Directing HDACi and TKI Target Therapy for Adult Ph-like ALL

Who this might be right for
LeukemiaLeukemia, AcuteLeukemia, Lymphoblastic+1 more
Nanfang Hospital, Southern Medical University 120
Very early researchNot Yet RecruitingNCT07498595
What this trial is testing

TILs Plus Third-Generation EGFR-TKI Therapy for TKI-Resistant NSCLC

Who this might be right for
EGFR-TKI-resistant Non-Small Cell Lung Cancer
Tianjin Medical University General Hospital 50
Early research (Phase 1)Looking for participantsNCT05304377
What this trial is testing

A Phase 1a/1b Study of ELVN-001 for the Treatment Chronic Myeloid Leukemia

Who this might be right for
Chronic Myeloid LeukemiaChronic Phase Chronic Myeloid Leukemia, BCR-ABL1 PositiveCml
Enliven Therapeutics 250
Large-scale testing (Phase 3)UnknownNCT03008109
What this trial is testing

Endostar Plus EGFR-TKI（Epidermal Growth Factor Receptor-Tyrosine-Kinase Inhibitor） as a Treatment of EGFR Mutation-positive NSCLC

Who this might be right for
Advanced CancerLung Cancer, Nonsmall Cell
Zaiwen Fan 80
Not applicableUnknownNCT03071705
What this trial is testing

Metformin Plus TKI Use in Patients With Non-Small Cell Lung Carcinoma

Who this might be right for
Non-Small Cell AdenocarcinomaTyrosine Kinase MutationEGFR Gene Mutation
Instituto Nacional de Cancerologia de Mexico 120
Not applicableActive Not RecruitingNCT05370469
What this trial is testing

Real-Time Monitoring of Symptoms in Lung Cancer Patients Receiving Oral Targeted Therapies

Who this might be right for
Lung CancerEGFR Gene MutationEGFR+6 more
University of Virginia 30
Testing effectiveness (Phase 2)WithdrawnNCT05039736
What this trial is testing

A Phase II Study to Evaluate the Effects of Sequential Therapy With the Anti c-MET/VEGFR Tyrosine Kinase Inhibitor (TKI), Cabozantinib, Followed by an Anti-PD-1 Antibody (Nivolumab) in Patients With Advanced HCC Who Progressed on First-line Therapy

Who this might be right for
Hepatocellular CarcinomaLiver Cancer
M.D. Anderson Cancer Center
Not applicableStudy completedNCT02616211
What this trial is testing

An Integrated Approach to Treating Recurrent Thoracic Carcinomas Resistant to Tyrosine Kinase Inhibitors

Who this might be right for
Adenocarcinoma of LungLung NeoplasmCancer of Lung+4 more
Mayo Clinic 15
Testing effectiveness (Phase 2)Ended earlyNCT02943473
What this trial is testing

Study on the Effect of Ibrutinib on High Risk Smoldering Multiple Myeloma Patients

Who this might be right for
High Risk Smoldering Multiple Myeloma
Icahn School of Medicine at Mount Sinai 9
Testing effectiveness (Phase 2)UnknownNCT03382795
What this trial is testing

Retreatment With Epidermal Growth Factor Receptor(EGFR) Tyrosine Kinase Inhibitor in EGFR Mutation Positive Patients

Who this might be right for
EGFR Positive Non-small Cell Lung Cancer
Korea University Guro Hospital 63
Not applicableNo Longer AvailableNCT02271139
What this trial is testing

Expanded Access Study of Alectinib for Participants With Anaplastic Lymphoma Kinase (ALK)-Rearranged Non-Small Cell Lung Cancer (NSCLC) After Disease Progression on or Intolerance to Prior ALK Tyrosine Kinase Inhibitor Therapy

Who this might be right for
Non-Small Cell Lung Cancer
Genentech, Inc.
Large-scale testing (Phase 3)Study completedNCT00116935
What this trial is testing

Study Comparing 12 Months Versus 36 Months of Imatinib in the Treatment of Gastrointestinal Stromal Tumor (GIST)

Who this might be right for
Sarcoma
Scandinavian Sarcoma Group 400
Early research (Phase 1)Study completedNCT05190068
What this trial is testing

HMPL-760 in Relapsed/Refractory B-Cell Non-Hodgkin's Lymphoma

Who this might be right for
B-Cell Non-Hodgkin's Lymphoma
Hutchmed 89
Not applicableEnded earlyNCT01073436
What this trial is testing

Discontinuation of Imatinib Mesylate in Patients With Chronic-Phase Chronic Myeloid Leukemia Previously Treated With Interferon-Alpha

Who this might be right for
Chronic Myeloid Leukemia
University of Michigan Rogel Cancer Center 7
Testing effectiveness (Phase 2)Study completedNCT00462943
What this trial is testing

Open Label Study of Subcutaneous Homoharringtonine (Omacetaxine Mepesuccinate) in Patients With Advanced CML

Who this might be right for
Chronic Myeloid Leukemia
Teva Branded Pharmaceutical Products R&D, Inc. 100
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