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Results for “Unresectable Colorectal Neoplasm Metastasis”

401 trials

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Showing 20 of 401 results

Early research (Phase 1)Looking for participantsNCT05176483
What this trial is testing

Study of Zanzalintinib in Combination With Immuno-Oncology Agents in Participants With Solid Tumors

Who this might be right for
Renal Cell Carcinoma (RCC)Metastatic Castration-Resistant Prostate Cancer (mCRPC)Urothelial Carcinoma (UC)+7 more
Exelixis 1,314
Testing effectiveness (Phase 2)Active Not RecruitingNCT05609370
What this trial is testing

A Study Investigating the Efficacy and Safety of LBL-007 Plus Tislelizumab in Combination With Bevacizumab Plus Fluoropyrimidine Versus Bevacizumab Plus Fluoropyrimidine in Participants With Unresectable or Metastatic Colorectal Cancer

Who this might be right for
Unresectable or Metastatic Microsatellite Stable/Mismatch Repair Proficient Colorectal Cancer
BeiGene 113
Not applicableStudy completedNCT06027775
What this trial is testing

Chemotherapy Alone Versus Chemotherapy Plus Targeted Therapy as Adjuvant Therapy for Initially Unresectable Colorectal Cancer Liver Metastases

Who this might be right for
Colorectal Cancer Metastatic
Fudan University 198
Early research (Phase 1)Study completedNCT00003439
What this trial is testing

Interleukin-12 in Treating Patients With Refractory Advanced-Stage Ovarian Cancer or Abdominal Cancer

Who this might be right for
Cancer
National Cancer Institute (NCI) 36
Early research (Phase 1)Looking for participantsNCT05985954
What this trial is testing

Open-label Phase 1b Study of Ulixertinib and Cetuximab or Ulixertinib in Combination With Cetuximab and Encorafenib in Patients With Unresectable or Metastatic Colorectal Cancer Who Have Previously Received EGFR or BRAF-directed Therapy

Who this might be right for
Metastatic Colorectal Cancer
M.D. Anderson Cancer Center 27
Large-scale testing (Phase 3)Study completedNCT00016380
What this trial is testing

Ondansetron With/Out Dexamethasone to Prevent Vomiting in Patients Receiving Radiation to the Upper Abdomen

Who this might be right for
Cancer
NCIC Clinical Trials Group 211
Testing effectiveness (Phase 2)WithdrawnNCT04001101
What this trial is testing

Anti-PD-1 +/- RT for MSI-H Solid Tumors

Who this might be right for
Microsatellite Instability HighMismatch Repair DeficiencyColorectal Cancer
University of Colorado, Denver
Large-scale testing (Phase 3)Study completedNCT00020501
What this trial is testing

Chemotherapy With or Without Isolated Hepatic Perfusion With Melphalan in Treating Patients With Colorectal Cancer That Has Spread to the Liver

Who this might be right for
Colorectal CancerMetastatic Cancer
National Institutes of Health Clinical Center (CC)
Testing effectiveness (Phase 2)UnknownNCT00081536
What this trial is testing

Aroplatin and Capecitabine in Patients With Advanced Colorectal Cancer Resistant to Standard Therapies

Who this might be right for
Colorectal Neoplasms
Aronex Pharmaceuticals 105
Early research (Phase 1)Looking for participantsNCT06853496
What this trial is testing

Study of a Tankyrase Inhibitor RK-582 for Patients With Unresectable Metastatic Colorectal Cancer

Who this might be right for
Unresectable Colorectal Neoplasm Metastasis
Eiji Shinozaki 48
Early research (Phase 1)Looking for participantsNCT05803382
What this trial is testing

Testing the Addition of an Anti-Cancer Drug, ZEN003694, to the Usual Chemotherapy Treatment (Capecitabine) for Metastatic or Unresectable Cancers

Who this might be right for
Metastatic Colorectal CarcinomaMetastatic Malignant Solid NeoplasmStage IV Colorectal Cancer AJCC v8+2 more
National Cancer Institute (NCI) 30
Early research (Phase 1)Active Not RecruitingNCT05907304
What this trial is testing

Assess Naporafenib (ERAS-254) Administered With Trametinib in Patients With RAS Q61X Mutations

Who this might be right for
Advanced or Metastatic Solid Tumors
Erasca, Inc. 86
Testing effectiveness (Phase 2)UnknownNCT03944252
What this trial is testing

Cetuximab + Avelumab or Avelumab Alone for Unresectable, Locally Advanced or Metastatic Squamous Cell Anal Carcinoma (SCCAC) Progressed After at Least One Line of Systemic Treatment (CARACAS)

Who this might be right for
Squamous Cell Anal Carcinoma
Gruppo Oncologico del Nord-Ovest 54
Testing effectiveness (Phase 2)Study completedNCT03981614
What this trial is testing

Binimetinib and Palbociclib or TAS-102 in Treating Patients With KRAS and NRAS Mutant Metastatic or Unresectable Colorectal Cancer

Who this might be right for
Metastatic Colorectal CarcinomaStage IV Colorectal Cancer AJCC v8Stage IVA Colorectal Cancer AJCC v8+3 more
Academic and Community Cancer Research United 102
Testing effectiveness (Phase 2)Study completedNCT01802684
What this trial is testing

OPTIMOX-aflibercept as First-line Therapy in Patients With Unresectable Metastatic Colorectal Cancer

Who this might be right for
Unresectable Metastatic Colorectal Cancer
GERCOR - Multidisciplinary Oncology Cooperative Group 49
Large-scale testing (Phase 3)Study completedNCT03231722
What this trial is testing

First Line mFOLFOXIRI + PANITUMUMAB vs mFOLFOX + PANITUMUMAB IN RAS AND BRAF WT METASTATIC COLORECTAL CANCER PATIENTS

Who this might be right for
Metastatic Colorectal Cancer
Gruppo Oncologico del Nord-Ovest 435
Testing effectiveness (Phase 2)Study completedNCT04744831
What this trial is testing

Trastuzumab Deruxtecan in Participants With HER2-overexpressing Advanced or Metastatic Colorectal Cancer

Who this might be right for
Advanced Colorectal Cancer
Daiichi Sankyo 122
Testing effectiveness (Phase 2)Looking for participantsNCT06148402
What this trial is testing

Fruquintinib Plus Camrelizumab and Capecitabine as Salvage Therapy After Progression on FOLFOXIRI-based First-line Treatment in Patients With Unresectable/Metastatic Colorectal Cancer

Who this might be right for
Unresectable/Metastatic Colorectal Cancer
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University 30
Not applicableEnded earlyNCT00087191
What this trial is testing

EF5 and Motexafin Lutetium in Detecting Tumor Cells in Patients With Abdominal or Non-Small Cell Lung Cancer

Who this might be right for
Advanced Adult Primary Liver CancerCarcinoma of the AppendixFallopian Tube Cancer+68 more
National Cancer Institute (NCI) 30
Testing effectiveness (Phase 2)Study completedNCT03142516
What this trial is testing

FOLFIRI + Panitumumab First-line Treatment in Elderly Patients With Unresectable Metastatic Colorectal Cancer, RAS/BRAF Wild-type and Good Performance Status

Who this might be right for
Colorectal NeoplasmsColorectal CarcinomaColorectal Cancer Metastatic+1 more
Grupo Espanol Multidisciplinario del Cancer Digestivo 20
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