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Results for “Unresectable Esophageal Squamous Cell Carcinoma”

109 trials

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Showing 20 of 109 results

Testing effectiveness (Phase 2)UnknownNCT05522894
What this trial is testing

AK104 Alone or in Combination With Chemotherapy in the First-line Treatment of ESCC

Who this might be right for
Unresectable Esophageal Squamous Cell CarcinomaLocally Advanced Esophageal Squamous Cell CarcinomaMetastatic Esophageal Squamous Cell Carcinoma
Chinese Academy of Medical Sciences 80
Not applicableLooking for participantsNCT07549100
What this trial is testing

Efficacy and Safety of Tislelizumab Plus Chemotherapy as Conversion Therapy in Unresectable Locally Advanced ESCC

Who this might be right for
Locally Advanced Esophageal Squamous Cell Carcinoma
Shandong Provincial Hospital 30
Testing effectiveness (Phase 2)Looking for participantsNCT06429839
What this trial is testing

Nimotuzumab Concurrent With Chemoradiotherapy for Esophageal Cancer Patients

Who this might be right for
Esophageal CancerNimotuzumabChemoradiotherapy+2 more
Cancer Institute and Hospital, Chinese Academy of Medical Sciences 55
Testing effectiveness (Phase 2)Looking for participantsNCT05592626
What this trial is testing

A Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors

Who this might be right for
Advanced Solid TumorsGenital Neoplasm, FemaleUrogenital Neoplasms+11 more
Marengo Therapeutics, Inc. 366
Early research (Phase 1)Study completedNCT03329950
What this trial is testing

CDX-1140 (CD40) as Monotherapy or in Combination in Patients With Advanced Malignancies

Who this might be right for
MelanomaNon-small Cell Lung CancerBreast Cancer+23 more
Celldex Therapeutics 132
Testing effectiveness (Phase 2)Looking for participantsNCT07733830
What this trial is testing

Comparing ICI Followed By CCRT And CCRT Followed By Immunotherapy In Unresectable LA-ESCC

Who this might be right for
Esophageal Cancer
Tianjin Medical University Cancer Institute and Hospital 120
Testing effectiveness (Phase 2)UnknownNCT00915850
What this trial is testing

Trial of Docetaxel, Cisplatin, Fluorouracil (5-FU) for Unresectable Advanced Esophageal Squamous Cell Carcinoma (ESCC)

Who this might be right for
Esophageal Cancer
Wakayama Medical University 32
Testing effectiveness (Phase 2)Study completedNCT03925870
What this trial is testing

KN046 in Subjects With Late Stage Esophageal Squamous Cell Carcinoma

Who this might be right for
Esophageal Squamous Cell Carcinoma
Jiangsu Alphamab Biopharmaceuticals Co., Ltd 45
Testing effectiveness (Phase 2)Looking for participantsNCT07339488
What this trial is testing

Intestinal Low-Dose Radiotherapy Plus Immunochemotherapy for Conversion of Borderline Resectable/Unresectable Esophageal Squamous Cell Carcinoma

Who this might be right for
Borderline Resectable CarcinomaUnresectable CancerEsophageal Squamous Cell Carcinoma (ESCC)+4 more
Chuangzhen Chen 43
Testing effectiveness (Phase 2)Looking for participantsNCT06675201
What this trial is testing

Neoantigen Vaccines in Esophageal Squamous Cell Carcinoma

Who this might be right for
Esophageal Squamous Cell Carcinoma (ESCC)Neoantigen-loaded Dendritic Cell VaccineImmune Checkpoint Inhibitors (ICIs)
Sichuan University 165
Testing effectiveness (Phase 2)Looking for participantsNCT06430658
What this trial is testing

Neoadjuvant Comprehensive Treatment for Unresectable Esophageal Cancer

Who this might be right for
Esophagus Cancer
Cancer Institute and Hospital, Chinese Academy of Medical Sciences 90
Early research (Phase 1)Study completedNCT03236935
What this trial is testing

Phase Ib of L-NMMA and Pembrolizumab

Who this might be right for
Non-Small Cell Lung CancerMalignant MelanomaHead and Neck Squamous Cell Carcinoma+3 more
The Methodist Hospital Research Institute 12
Testing effectiveness (Phase 2)Ended earlyNCT04032704
What this trial is testing

Ladiratuzumab Vedotin in Advanced Solid Tumors

Who this might be right for
Small Cell Lung CancerNon-small Cell Lung Cancer, SquamousNon-small Cell Lung Cancer, Non-squamous+6 more
Seagen Inc. 205
Testing effectiveness (Phase 2)Looking for participantsNCT06780111
What this trial is testing

Substudy 06E: Umbrella Study of Combination Therapies in Esophageal Cancer (MK-3475-06E/KEYMAKER-U06)

Who this might be right for
Esophageal Squamous Cell Carcinoma
Merck Sharp & Dohme LLC 298
Testing effectiveness (Phase 2)Looking for participantsNCT06173986
What this trial is testing

Immunotherapy in Combination With Chemoradiotherapy in Unresectable Locally Advanced Esophageal Cancer

Who this might be right for
Esophageal Squamous Cell CarcinomaUnresectable Locally Advanced Esophageal Cancer
Shanghai Chest Hospital 50
Testing effectiveness (Phase 2)Looking for participantsNCT06709417
What this trial is testing

A Phase II Clinical Study of Sintilimab Combined with Chemotherapy Followed by Concurrent Chemoradiotherapy for Locally Advanced Unresectable Esophageal Squamous Cell Carcinoma (ESCC) (NICE-CS)

Who this might be right for
Esophageal Squamous Cell Carcinoma (ESCC)
Shanghai Chest Hospital 52
Testing effectiveness (Phase 2)Ended earlyNCT05461794
What this trial is testing

Study To Investigate the Efficacy and Safety of Sitravatinib in Combination With Tislelizumab in Participants With Esophageal Squamous Cell Carcinoma

Who this might be right for
Esophageal Squamous Cell Carcinoma
BeiGene 96
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07128693
What this trial is testing

A Single-center, Multicohort, Phase II Clinical Study Evaluating the Combination Therapy of Sacituzumab Tirumotecan in Patients With Unresectable, Locally Advanced, Recurrent, or Metastatic Esophageal Squamous Cell Carcinoma

Who this might be right for
Esophageal Squamous Cell Carcinoma
The First Affiliated Hospital of Zhengzhou University 60
Testing effectiveness (Phase 2)Looking for participantsNCT06265285
What this trial is testing

Comparison of In-Home Versus In-Clinic Administration of Subcutaneous Nivolumab Through Cancer CARE (Connected Access and Remote Expertise) Beyond Walls (CCBW) Program

Who this might be right for
Advanced Esophageal Squamous Cell CarcinomaAdvanced Renal Cell CarcinomaClinical Stage II Esophageal Squamous Cell Carcinoma AJCC v8+28 more
Mayo Clinic 50
Testing effectiveness (Phase 2)UnknownNCT00003326
What this trial is testing

Paclitaxel in Treating Patients With Metastatic, Recurrent, or Unresectable Cancer of the Esophagus

Who this might be right for
Esophageal Cancer
Theradex 100
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