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Results for “Unresectable Locally Advanced”

1,022 trials

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Showing 20 of 1,022 results

Large-scale testing (Phase 3)Looking for participantsNCT06767527
What this trial is testing

AK112 or Placebo Plus Nab-Paclitaxel as First-line Treatment in Inoperable Locally Advanced/ Metastatic Triple-negative Breast Cancer

Who this might be right for
Triple-Negative Breast Cancer (TNBC)
Akeso 416
Large-scale testing (Phase 3)Looking for participantsNCT07103668
What this trial is testing

A Phase III Randomized Study in CLDN18.2-positive Unresectable Locally Advanced Gastric Cancer Patients

Who this might be right for
Gastric Adenocarcinoma
Suzhou Immunofoco Biotechnology Co., Ltd 150
Testing effectiveness (Phase 2)Study completedNCT00025168
What this trial is testing

Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Locally Advanced Unresectable Pancreatic Cancer

Who this might be right for
Pancreatic Cancer
Wake Forest University Health Sciences 20
Early research (Phase 1)Active Not RecruitingNCT05311397
What this trial is testing

A166 in Patients With Advanced Solid Malignant Tumors

Who this might be right for
Breast Cancer
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. 120
Not applicableLooking for participantsNCT07024680
What this trial is testing

Real World Study of Effectiveness of Sunitinib or Sorafenib to Chinese Unresectable Locally Advanced or Metastatic PRCC

Who this might be right for
Papillary Renal Cell Carcinoma
AstraZeneca 150
Early research (Phase 1)Looking for participantsNCT07524322
What this trial is testing

Study of RGT-490 in Patients With PIK3CA-Mutated Advanced Solid Tumors

Who this might be right for
Breast CancerOvarian CancerEndometrial Cancer+6 more
Regor Pharmaceuticals Inc. 63
Testing effectiveness (Phase 2)Study completedNCT02761057
What this trial is testing

Testing Cabozantinib, Crizotinib, Savolitinib and Sunitinib in Kidney Cancer Which Has Progressed

Who this might be right for
Locally Advanced Papillary Renal Cell CarcinomaMetastatic Papillary Renal Cell CarcinomaStage III Renal Cell Cancer AJCC v7+4 more
National Cancer Institute (NCI) 152
Large-scale testing (Phase 3)Ended earlyNCT04866017
What this trial is testing

Compare Ociperlimab Plus Tislelizumab Versus Durvalumab Following Concurrent Chemoradiotherapy (cCRT) in Participants With Stage III Unresectable Non-Small Cell Lung Cancer

Who this might be right for
Non Small Cell Lung Cancer
BeiGene 63
Testing effectiveness (Phase 2)Study completedNCT03623854
What this trial is testing

Nivolumab and Relatlimab in Treating Participants With Advanced Chordoma

Who this might be right for
ChordomaLocally Advanced ChordomaMetastatic Chordoma+1 more
Jonsson Comprehensive Cancer Center 10
Early research (Phase 1)Ended earlyNCT02751528
What this trial is testing

QUILT-3.013: Study of Ad5 [E1-, E2b-]-HER2/Neu Vaccine (ETBX-021) in Subjects With Unresectable Locally Advanced or Metastatic HER2-Expressing Breast Cancer

Who this might be right for
Cancer
NantBioScience, Inc. 3
Testing effectiveness (Phase 2)Study completedNCT04732494
What this trial is testing

Anti-PD-1 Monoclonal Antibody Tislelizumab (BGB-A317) Combined With or Without Anti-TIGIT Monoclonal Antibody Ociperlimab (BGB-A1217) in Participants With Recurrent or Metastatic Esophageal Squamous Cell Carcinoma

Who this might be right for
Esophageal Squamous Cell Carcinoma
BeiGene 125
Testing effectiveness (Phase 2)Study completedNCT01286766
What this trial is testing

Neoadjuvant Combination Chemotherapy of DCS and DCF in Patients With Locally Advanced Gastric Adenocarcinoma

Who this might be right for
Gastric Cancer
Yonsei University 6
Large-scale testing (Phase 3)Ended earlyNCT02288377
What this trial is testing

A Study Evaluating Lanreotide as Maintenance Therapy in Patients With Non-Resectable Duodeno-Pancreatic Neuroendocrine Tumors (REMINET)

Who this might be right for
Metastatic/Locally Advanced, Non-resectable, Duodeno-pancreatic Neuroendocrine Tumours
Federation Francophone de Cancerologie Digestive 53
Large-scale testing (Phase 3)Study completedNCT00262769
What this trial is testing

Gemcitabine With or Without Cisplatin in Treating Patients With Unresectable Locally Advanced or Metastatic Cholangiocarcinoma or Other Biliary Tract Tumors

Who this might be right for
Extrahepatic Bile Duct CancerGallbladder Cancer
University College, London 324
Large-scale testing (Phase 3)Study completedNCT05008783
What this trial is testing

AK104 in the First-line Treatment of Locally Advanced Unresectable or Metastatic G/GEJ Adenocarcinoma

Who this might be right for
Gastric AdenocarcinomaGastroesophageal Junction Adenocarcinoma
Akeso 610
Testing effectiveness (Phase 2)Ended earlyNCT00271323
What this trial is testing

Safety Study of Docetaxel/Cisplatin Induction Therapy Followed by Concurrent Chemoradiotherapy or Concurrent Chemoradiotherapy Followed by Consolidation Docetaxel/Cisplatin in NSCLC Patients

Who this might be right for
Non-Small-Cell Lung Carcinoma
Sanofi 14
Testing effectiveness (Phase 2)Looking for participantsNCT07435454
What this trial is testing

Exploratory Clinical Trial of Oral Paclitaxel Plus Radiotherapy in Patients With Locally Advanced Unresectable Esophageal Squamous Cell Carcinoma

Who this might be right for
Locally Advanced Unresectable Esophageal Squamous Cell Carcinoma
Jiangsu Cancer Institute & Hospital 22
Testing effectiveness (Phase 2)Looking for participantsNCT05136196
What this trial is testing

BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study

Who this might be right for
Clinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8+22 more
National Cancer Institute (NCI)
Testing effectiveness (Phase 2)Active Not RecruitingNCT05836571
What this trial is testing

Testing Ipilimumab and Nivolumab Combination With or Without Cabozantinib in People >= 18 Years Old With Advanced Soft Tissue Sarcoma

Who this might be right for
Locally Advanced Extraskeletal Myxoid ChondrosarcomaLocally Advanced LeiomyosarcomaLocally Advanced Liposarcoma+7 more
National Cancer Institute LAO 66
Not applicableStudy completedNCT03645330
What this trial is testing

Atezolizumab in Patients With Unresectable, Locally Advanced or Metastatic NSCLC (J-TAIL)

Who this might be right for
Non-small-Cell Lung Cancer
Chugai Pharmaceutical 1,026
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