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Results for “Unresectable Locally Advanced”

1,061 trials

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Showing 20 of 1,061 results

Testing effectiveness (Phase 2)Ended earlyNCT04375527
What this trial is testing

Binimetinib and Nivolumab for the Treatment of Locally Advanced Unresectable or Metastatic BRAF V600 Wildtype Melanoma

Who this might be right for
Clinical Stage III Cutaneous Melanoma AJCC V8Clinical Stage IV Cutaneous Melanoma AJCC V8Locally Advanced Cutaneous Melanoma+8 more
Jonsson Comprehensive Cancer Center 3
Testing effectiveness (Phase 2)Active Not RecruitingNCT05383196
What this trial is testing

Onvansertib + Paclitaxel In TNBC

Who this might be right for
Breast CancerInvasive Breast CancerUnresectable Breast Carcinoma+7 more
Antonio Giordano, MD 50
Testing effectiveness (Phase 2)Study completedNCT06281886
What this trial is testing

Induction Immuno-chemotherapy and Concurrent Chemoradiotherapy With or Without Apatinib in Unresectable, Locally Advanced Esophageal Squamous Cell Carcinoma

Who this might be right for
Esophageal Squamous Cell CarcinomaEfficacyToxicity
Sun Yat-sen University 170
Testing effectiveness (Phase 2)Looking for participantsNCT07235566
What this trial is testing

MRG003 and Pucotenlimab to Treat Locally Advanced or Metastatic ATC/PDTC

Who this might be right for
Thyroid Cancer
Fudan University 60
Testing effectiveness (Phase 2)Looking for participantsNCT06732856
What this trial is testing

A Phase Ib/II Trial of Neoadjuvant Zolbetuximab Plus Docetaxel, Oxaliplatin and S-1 Chemotherapy in Patients With Locally Advanced Gastric Cancer

Who this might be right for
Stomach NeoplasmGastric (Stomach) Cancer
Asan Medical Center 57
Not applicableStudy completedNCT04560270
What this trial is testing

CIrculating Tumor DNA for Monitoring Response to First Line Chemotherapy in Unresectable PANcreatic Cancer

Who this might be right for
Pancreatic CancerCirculating Tumor DNAKRAS Mutation-Related Tumors
Poitiers University Hospital 69
Testing effectiveness (Phase 2)Active Not RecruitingNCT03093922
What this trial is testing

Two Dosing Schedules of Atezolizumab in Combination With Gemcitabine and Cisplatin as First-Line Treatment for Metastatic Bladder Cancer

Who this might be right for
Urothelial CarcinomaLocally AdvancedUnresectable
Memorial Sloan Kettering Cancer Center 32
Early research (Phase 1)WithdrawnNCT06626256
What this trial is testing

STIL101 for Injection for the Treatment of Locally Advanced, Metastatic or Unresectable Pancreatic Cancer, Colorectal Cancer, Renal Cell Cancer, Cervical Cancer and Melanoma

Who this might be right for
Locally Advanced Cervical CarcinomaLocally Advanced Colorectal CarcinomaLocally Advanced Malignant Solid Neoplasm+24 more
City of Hope Medical Center
Large-scale testing (Phase 3)Looking for participantsNCT06901531
What this trial is testing

Zolbetuximab Together With Pembrolizumab and Chemotherapy in Adults With Gastric Cancer

Who this might be right for
Locally Advanced Unresectable Gastroesophageal Junction (GEJ) Adenocarcinoma or CancerLocally Advanced Unresectable Gastric Adenocarcinoma or CancerMetastatic Gastric Adenocarcinoma or Cancer+1 more
Astellas Pharma Global Development, Inc.
Testing effectiveness (Phase 2)Looking for participantsNCT06452602
What this trial is testing

Induction Immunochemotherapy Followed by Concurrent Chemoradiotherapy in Patients With ESCC.

Who this might be right for
Esophageal Cancer
Tianjin Medical University Cancer Institute and Hospital 60
Testing effectiveness (Phase 2)Ended earlyNCT00109850
What this trial is testing

S0414 Cetuximab, Combo Chemo, and RT in Locally Advanced Esophageal Cancer

Who this might be right for
Esophageal Cancer
SWOG Cancer Research Network 22
Not applicableLooking for participantsNCT07607119
What this trial is testing

PULSAR Combined With Immunotherapy for Unresectable Locally Advanced Gastric Cancer

Who this might be right for
Gastric AdenocarcinomaStomach NeoplasmsLocally Advanced Gastric Cancer+1 more
Samsung Medical Center 53
Early research (Phase 1)Looking for participantsNCT05458219
What this trial is testing

A First-in-human Study of IBI343 in Subjects With Locally Advanced Unresectable or Metastatic Solid Tumors

Who this might be right for
Locally Advanced Unresectable or Metastatic Solid Tumors
Innovent Biologics (Suzhou) Co. Ltd. 470
Early research (Phase 1)Looking for participantsNCT06493864
What this trial is testing

BL-B16D1 in Patients With Unresectable Locally Advanced or Metastatic Breast Cancer and Other Solid Tumors

Who this might be right for
Breast CancerSolid Tumor
Sichuan Baili Pharmaceutical Co., Ltd. 21
Testing effectiveness (Phase 2)Study completedNCT00408564
What this trial is testing

Cetuximab, Gemcitabine, and Oxaliplatin Followed By Surgery or External-Beam Radiation Therapy and Capecitabine in Treating Patients With Locally Advanced, Nonmetastatic Pancreatic Cancer That Cannot Be Removed By Surgery

Who this might be right for
Pancreatic Cancer
Medical University of South Carolina 39
Post-approval studies (Phase 4)Not Yet RecruitingNCT07829757
What this trial is testing

Zolbetuximab Given With mFOLFOX6 or CAPOX Chemotherapy in Indian Adults With Gastric Cancer

Who this might be right for
Locally Advanced Unresectable Gastroesophageal Junction (GEJ) Adenocarcinoma or CancerLocally Advanced Unresectable Gastric Adenocarcinoma or CancerMetastatic Gastric Adenocarcinoma or Cancer+1 more
Astellas Pharma Global Development, Inc.
Testing effectiveness (Phase 2)Active Not RecruitingNCT07654530
What this trial is testing

Sintilimab Combined With Ipilimumab (N01) Plus AG as First-line Therapy for uBTC.

Who this might be right for
Biliary Tract Cancers (BTC)
Tianjin Medical University Cancer Institute and Hospital 107
Large-scale testing (Phase 3)Ended earlyNCT02186301
What this trial is testing

TIGER-1: Safety and Efficacy Study of Rociletinib (CO-1686) or Erlotinib in Patients With EGFR-mutant/Metastatic NSCLC Who Have Not Had Any Previous EGFR Directed Therapy

Who this might be right for
Non-Small Cell Lung Cancer
Clovis Oncology, Inc. 100
Testing effectiveness (Phase 2)UnknownNCT05338619
What this trial is testing

Lazertinib as Consolidation Therapy in Patients With Locally Advanced, Unresectable, EGFR-Mutant Non-Small Cell Lung Cancer (Stage III) Following Chemoradiation Therapy

Who this might be right for
Non-small Cell Lung Cancer Stage IIIEGFR Positive Non-small Cell Lung CancerNon-squamous Non-small-cell Lung Cancer
Sung Yong Lee 77
Testing effectiveness (Phase 2)Ended earlyNCT01794845
What this trial is testing

Cetuximab + Taxotere With Low Dose Fractionated Radiation for Head and Neck Carcinoma

Who this might be right for
Squamous Cell CarcinomaHead and Neck CancerRecurrent Disease
University of Miami 5
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