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Results for “Unresectable Locally Advanced Colorectal Cancer”

54 trials

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Showing 20 of 54 results

Not applicableStudy completedNCT00097578
What this trial is testing

Avastin With Chemotherapy for Treatment of Metastatic or Advanced and Unresectable Colorectal Adenocarcinoma

Who this might be right for
Colorectal Cancer
Genentech, Inc. 1,953
Not applicableActive Not RecruitingNCT05487248
What this trial is testing

On-treatment ctDNA Changes in Chemo-refractory Colorectal Cancer Patients

Who this might be right for
Unresectable Locally Advanced Colorectal CancerMetastatic Colorectal CancerCandidate for Third-line or Subsequent Lines of Therapy
Jules Bordet Institute 103
Testing effectiveness (Phase 2)Study completedNCT00077337
What this trial is testing

FR901228 in Treating Patients With Previously Treated Unresectable Locally Advanced or Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer
SWOG Cancer Research Network
Testing effectiveness (Phase 2)Looking for participantsNCT06051695
What this trial is testing

Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression

Who this might be right for
Solid Tumor, AdultColorectal CancerNSCLC+17 more
A2 Biotherapeutics Inc. 474
Early research (Phase 1)Study completedNCT03821233
What this trial is testing

A Dose Finding Study of ZW49 in Patients With HER2-Positive Cancers

Who this might be right for
HER2-expressing Cancers
Zymeworks BC Inc. 112
Not applicableLooking for participantsNCT06244537
What this trial is testing

Study on the Safety and Efficacy of MR-Linac Technique in Patients With Unresectable Locally Advanced Colon Cancer

Who this might be right for
Safety and Efficacy
Sichuan Cancer Hospital and Research Institute 20
Early research (Phase 1)Study completedNCT05954871
What this trial is testing

Study to Evaluate the Safety, Pharmacokinetics, and Activity of GDC-1971 in Combination With Either Osimertinib in Participants With Unresectable, Locally Advanced, or Metastatic Non-Small Cell Lung Cancer, or With Cetuximab in Participants With Metastatic Colorectal Cancer

Who this might be right for
Colorectal CancerNon-Small Cell Lung Cancer
Genentech, Inc. 10
Testing effectiveness (Phase 2)Ended earlyNCT05091528
What this trial is testing

A Safety and Activity Study of SBT6050 in Combination With Other HER2-directed Therapies for HER2-positive Cancers

Who this might be right for
HER2-positive Breast CancerHER2-positive Gastric CancerHER2-positive Colorectal Cancer+1 more
Silverback Therapeutics 2
Early research (Phase 1)Study completedNCT04672434
What this trial is testing

Sym024 Monotherapy and in Combination With Sym021 in Patients With Advanced Solid Tumor Malignancies

Who this might be right for
Metastatic CancerSolid Tumor
Symphogen A/S 48
Testing effectiveness (Phase 2)Active Not RecruitingNCT04117945
What this trial is testing

Regorafenib, With Cetuximab or Panitumumab, for the Treatment of Unresectable, Locally Advanced, or Metastatic Colorectal Cancer

Who this might be right for
BRAF V600E NegativeKRAS Gene Mutation NegativeLocally Advanced Unresectable Colorectal Adenocarcinoma+10 more
Academic and Community Cancer Research United 22
Testing effectiveness (Phase 2)Active Not RecruitingNCT05736731
What this trial is testing

Evaluate the Safety and Efficacy of A2B530, a Logic-gated CAR T, in Participants With Solid Tumors That Express CEA and Have Lost HLA-A*02 Expression

Who this might be right for
Solid Tumor, AdultSolid TumorPancreatic Cancer+13 more
A2 Biotherapeutics Inc. 160
Early research (Phase 1)Looking for participantsNCT06440005
What this trial is testing

Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors

Who this might be right for
CancerAdvanced CancerLocally Advanced Carcinoma+8 more
Angiex, Inc. 80
Early research (Phase 1)Ended earlyNCT05631574
What this trial is testing

Study of Covalent Menin Inhibitor BMF-219 in Adult Patients With KRAS Driven Non-Small Cell Lung Cancer, Pancreatic Cancer, and Colorectal Cancer

Who this might be right for
Non Small Cell Lung CancerPancreatic CancerColorectal Cancer+14 more
Biomea Fusion Inc. 13
Testing effectiveness (Phase 2)Looking for participantsNCT07042685
What this trial is testing

Trial of 5-Fluorouracil (5FU)-Based Therapy in Combination With Fruquintinib in Patients With Locally Advanced Unresectable or Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer (CRC)
The Methodist Hospital Research Institute 50
Early research (Phase 1)WithdrawnNCT06626256
What this trial is testing

STIL101 for Injection for the Treatment of Locally Advanced, Metastatic or Unresectable Pancreatic Cancer, Colorectal Cancer, Renal Cell Cancer, Cervical Cancer and Melanoma

Who this might be right for
Locally Advanced Cervical CarcinomaLocally Advanced Colorectal CarcinomaLocally Advanced Malignant Solid Neoplasm+24 more
City of Hope Medical Center
Testing effectiveness (Phase 2)UnknownNCT03944252
What this trial is testing

Cetuximab + Avelumab or Avelumab Alone for Unresectable, Locally Advanced or Metastatic Squamous Cell Anal Carcinoma (SCCAC) Progressed After at Least One Line of Systemic Treatment (CARACAS)

Who this might be right for
Squamous Cell Anal Carcinoma
Gruppo Oncologico del Nord-Ovest 54
Early research (Phase 1)Looking for participantsNCT07066657
What this trial is testing

MRG007 (ARR-217) in Patients With Advanced Solid Tumors

Who this might be right for
Locally Advanced or Metastatic Solid TumorsColorectal CancerGastric Cancer+1 more
Lepu Biopharma Co., Ltd. 405
Testing effectiveness (Phase 2)Ended earlyNCT02010567
What this trial is testing

Neoadjuvant Chemoradiotherapy With CRLX-101 and Capecitabine for Rectal Cancer

Who this might be right for
Rectal Cancer
UNC Lineberger Comprehensive Cancer Center 32
Testing effectiveness (Phase 2)Study completedNCT00166465
What this trial is testing

Stage IV Colorectal CA ALIMTA

Who this might be right for
Locally Advanced Unresectable or Stage IV Colorectal Cancer
Mayo Clinic 200
Testing effectiveness (Phase 2)Active Not RecruitingNCT05167448
What this trial is testing

ES104 in Patients With Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
Elpiscience (Suzhou) Biopharma, Ltd. 58
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