Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Unresectable Locally Advanced Squamous Cell Carcinoma of Head and Neck”

79 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 79 results

Large-scale testing (Phase 3)WithdrawnNCT01345084
What this trial is testing

Study Comparing Radiation Therapy and Chemotherapy With or Without Nimotuzumab

Who this might be right for
CarcinomaHead and Neck Cancer
Eurofarma Laboratorios S.A.
Large-scale testing (Phase 3)UnknownNCT00999700
What this trial is testing

Induction Chemotherapy Followed by Cetuximab Plus Definitive Radiotherapy Versus Radiation Plus Cisplatin

Who this might be right for
Squamous Cell Carcinoma of the Head and Neck
Gruppo Oncologico del Nord-Ovest 282
Testing effectiveness (Phase 2)Study completedNCT01181401
What this trial is testing

InductionChemo-Radio-Antibody-Treatment

Who this might be right for
Squamous Cell Carcinoma of the HeadSquamous Cell Carcinoma of the Neck
Charite University, Berlin, Germany 94
Testing effectiveness (Phase 2)Ended earlyNCT04844073
What this trial is testing

TAK-186 (Also Known as MVC-101) in Adults With Advanced or Metastatic Cancer

Who this might be right for
Squamous Cell Cancer of Head and Neck (SCCHN)Non-small Cell Lung Cancer (NSCLC)Colorectal Cancer
Takeda 95
Testing effectiveness (Phase 2)Looking for participantsNCT05136196
What this trial is testing

BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study

Who this might be right for
Clinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8+22 more
National Cancer Institute (NCI)
Testing effectiveness (Phase 2)Ended earlyNCT00109850
What this trial is testing

S0414 Cetuximab, Combo Chemo, and RT in Locally Advanced Esophageal Cancer

Who this might be right for
Esophageal Cancer
SWOG Cancer Research Network 22
Testing effectiveness (Phase 2)Looking for participantsNCT07435454
What this trial is testing

Exploratory Clinical Trial of Oral Paclitaxel Plus Radiotherapy in Patients With Locally Advanced Unresectable Esophageal Squamous Cell Carcinoma

Who this might be right for
Locally Advanced Unresectable Esophageal Squamous Cell Carcinoma
Jiangsu Cancer Institute & Hospital 22
Testing effectiveness (Phase 2)Study completedNCT01333085
What this trial is testing

Everolimus, Carboplatin, and Paclitaxel in Locally Advanced Head and Neck Cancer That Cannot Be Removed by Surgery

Who this might be right for
Head and Neck Cancer
GERCOR - Multidisciplinary Oncology Cooperative Group 49
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07128693
What this trial is testing

A Single-center, Multicohort, Phase II Clinical Study Evaluating the Combination Therapy of Sacituzumab Tirumotecan in Patients With Unresectable, Locally Advanced, Recurrent, or Metastatic Esophageal Squamous Cell Carcinoma

Who this might be right for
Esophageal Squamous Cell Carcinoma
The First Affiliated Hospital of Zhengzhou University 60
Testing effectiveness (Phase 2)Study completedNCT01689194
What this trial is testing

Efficacy Study of Genexol-PM and Cisplatin in Locally Advanced Head and Neck Cancer

Who this might be right for
Locally Advanced Head and Neck Squamous Cell Carcinoma
Seoul National University Hospital 53
Large-scale testing (Phase 3)Looking for participantsNCT07554456
What this trial is testing

BL-B01D1 in Combination With Tislelizumab ±5-Fluorouracil Versus Platinum-Based Chemotherapy Plus Tislelizumab as First-line Treatment in Patients With Unresectable, Locally Advanced Recurrent or Metastatic Esophageal Squamous Cell Carcinoma(PANKU-Esophagus02)

Who this might be right for
Esophageal Squamous Cell Carcinoma
Sichuan Baili Pharmaceutical Co., Ltd. 90
Testing effectiveness (Phase 2)Study completedNCT03624231
What this trial is testing

Feasibility & Efficacy of Durvalumab+Tremelimumab+RT and Durvalumab+RT in Non-resect. Locally Advanced HPVnegativ HNSCC

Who this might be right for
Squamous Cell Carcinoma of the Head and Neck
Ulrich Keilholz 18
Testing effectiveness (Phase 2)Looking for participantsNCT07086469
What this trial is testing

Surufatinib in Combination With Neoadjuvant Chemo-immunotherapy and Concurrent Chemoradiotherapy for Patients With Unresectable Locally Advanced Esophageal Squamous Cell Carcinoma

Who this might be right for
ToripalimabSurufatinibNeoadjuvant Immunochemotherapy+2 more
Sun Yat-sen University 69
Testing effectiveness (Phase 2)UnknownNCT01301248
What this trial is testing

Cisplatin Chemoradiation With or Without Cetuximab for Locoregionally Advanced Squamous Cell Carcinomas (SCC) of the Head and Neck

Who this might be right for
Head and Neck NeoplasmsAJCC Stage III/IV
Theagenio Cancer Hospital 80
Testing effectiveness (Phase 2)Looking for participantsNCT06978829
What this trial is testing

Cetuximab + Tislelizumab + Chemotherapy in the Treatment of Unresectable LA HNSCC

Who this might be right for
LA HNSCC
Daping Hospital and the Research Institute of Surgery of the Third Military Medical University 42
Not applicableEnded earlyNCT01303237
What this trial is testing

A Post Marketing Surveillance Study to Assess the Safety and Efficacy of Cetuximab Plus Radiotherapy in Locally Advanced Squamous Cell Carcinoma of the Head and Neck

Who this might be right for
Unresectable Locally Advanced Squamous Cell Carcinoma of Head and NeckLA SCCHN
Merck KGaA, Darmstadt, Germany 88
Early research (Phase 1)Active Not RecruitingNCT04007744
What this trial is testing

Sonidegib and Pembrolizumab in Treating Patients With Advanced Solid Tumors

Who this might be right for
Clinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage III Gastric Cancer AJCC v8Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8+19 more
Mayo Clinic 36
Testing effectiveness (Phase 2)Looking for participantsNCT06988956
What this trial is testing

Nimotuzumab Plus Definite Chemoradiotherapy(dCRT) in Elderly Patients With Esophageal Squamous Cell Carcinoma

Who this might be right for
Esophageal Squamous Cell Carcinoma
The First Affiliated Hospital with Nanjing Medical University 95
Testing effectiveness (Phase 2)Looking for participantsNCT06675201
What this trial is testing

Neoantigen Vaccines in Esophageal Squamous Cell Carcinoma

Who this might be right for
Esophageal Squamous Cell Carcinoma (ESCC)Neoantigen-loaded Dendritic Cell VaccineImmune Checkpoint Inhibitors (ICIs)
Sichuan University 165
Testing effectiveness (Phase 2)Looking for participantsNCT06682793
What this trial is testing

Evaluate the Safety and Efficacy of A2B395, an Allogeneic Logic-gated CAR T, in Participants With Solid Tumors That Express EGFR and Have Lost HLA-A*02 Expression

Who this might be right for
Solid Tumor, AdultColorectal CancerNon-Small Cell Lung+14 more
A2 Biotherapeutics Inc. 240
Next Page
150