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Results for “Unresectable Metastatic Colo-rectal Cancer”

311 trials

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Showing 20 of 311 results

Testing effectiveness (Phase 2)Looking for participantsNCT05086692
What this trial is testing

A Beta-only IL-2 ImmunoTherapY Study

Who this might be right for
Advanced Solid TumorUnresectable Solid TumorClear Cell Renal Cell Carcinoma+34 more
Medicenna Therapeutics, Inc. 115
Large-scale testing (Phase 3)UnknownNCT00610636
What this trial is testing

Treatment Outcomes of Hepatic Metastasis After FOLFOX-4 Therapy

Who this might be right for
Colorectal Cancer
National Taiwan University Hospital 200
Large-scale testing (Phase 3)Active Not RecruitingNCT04230187
What this trial is testing

Bevacizumab Plus mFOLFOXIRI as First-line Treatment for Patients With Unresectable Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer
Yanhong Deng 528
Not applicableEnded earlyNCT03765736
What this trial is testing

Genetic Testing in Screening Patients With Metastatic or Unresectable Colon or Rectal Cancer for a COLOMATE Trial

Who this might be right for
Metastatic Colon AdenocarcinomaMetastatic Rectal AdenocarcinomaStage III Colon Cancer AJCC v8+17 more
Academic and Community Cancer Research United 199
Large-scale testing (Phase 3)Looking for participantsNCT06662786
What this trial is testing

Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer

Who this might be right for
Colorectal Neoplasms
Janssen Research & Development, LLC 1,000
Early research (Phase 1)Study completedNCT00667641
What this trial is testing

Paclitaxel and Bortezomib in Treating Patients With Metastatic or Unresectable Malignant Solid Tumors

Who this might be right for
Breast CancerColorectal CancerHead and Neck Cancer+6 more
University of Medicine and Dentistry of New Jersey 16
Early research (Phase 1)Study completedNCT01437007
What this trial is testing

TKM 080301 for Primary or Secondary Liver Cancer

Who this might be right for
Colorectal Cancer With Hepatic MetastasesPancreas Cancer With Hepatic MetastaseGastric Cancer With Hepatic Metastase+2 more
National Cancer Institute (NCI) 1
Testing effectiveness (Phase 2)UnknownNCT00852228
What this trial is testing

Optimal Control of Liver Metastases From Colorectal Cancer With Cetuximab and Hepatic Artery Infusion of Chemotherapy

Who this might be right for
Metastatic Colorectal CancerLiver MetastasesHepatic Lesions
Association pour la Recherche sur le Temps Biologique et la Chronothérapie 60
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06835179
What this trial is testing

SBRT Combined With CAPEOX, Bevacizumab, and PD-1 Inhibitor for the Treatment of RAS-Mutant, MSS-Type, Unresectable Metastatic Colorectal Cancer.

Who this might be right for
Unresectable Metastatic Colorectal CancerMicrosatellite Stable (MSS) Colorectal Cancer (CRC)RAS-mutant Colorectal Cancer
The First Affiliated Hospital with Nanjing Medical University 28
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07353268
What this trial is testing

Phase Ib/II Study of QL1706 + Fruquintinib + SCRT vs. Standard Third-Line Therapy in Unresectable Liver-Metastatic pMMR/MSS Colorectal Cancer: Safety, Tolerability, and Efficacy.

Who this might be right for
Colorectal Cancer
Tao Zhang 76
Large-scale testing (Phase 3)Active Not RecruitingNCT03635021
What this trial is testing

Study to Evaluate the Efficacy of FOLFOX + Panitumumab Followed by FOLFIRI + Bevacizumab (Sequence 1) Versus FOLFOX + Bevacizumab Followed by FOLFIRI + Panitumumab (Sequence 2) in Untreated Patients With Wild-type RAS Metastatic, Primary Left-sided, Unresectable Colorectal Cancer

Who this might be right for
Colorectal Cancer
Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD) 419
Testing effectiveness (Phase 2)Looking for participantsNCT02185443
What this trial is testing

Stereotactic Body Radiation Therapy (SBRT) for Unresectable Liver Metastases

Who this might be right for
Liver MetastasesColorectal CancerAnal Canal Cancer+1 more
University of Sao Paulo 43
Testing effectiveness (Phase 2)Ended earlyNCT04844073
What this trial is testing

TAK-186 (Also Known as MVC-101) in Adults With Advanced or Metastatic Cancer

Who this might be right for
Squamous Cell Cancer of Head and Neck (SCCHN)Non-small Cell Lung Cancer (NSCLC)Colorectal Cancer
Takeda 95
Testing effectiveness (Phase 2)Looking for participantsNCT07147231
What this trial is testing

Testing the Effectiveness of the Anti-cancer Drug Pidnarulex (CX-5461), in Combination With Another Anti-cancer Drug Cemiplimab (REGN2810), in Treating Refractory Microsatellite Stable Colorectal Cancer

Who this might be right for
Metastatic Colorectal AdenocarcinomaRefractory Colorectal AdenocarcinomaStage III Colorectal Cancer AJCC v8+2 more
National Cancer Institute (NCI) 86
Large-scale testing (Phase 3)Looking for participantsNCT06733038
What this trial is testing

FOLFOXIRI Plus Bevacizumab With or Without Atezolizumab as 1st Line Treatment of pMMR and IS IC-High Metastatic Colorectal Cancer Patients.

Who this might be right for
Colorectal Cancer
Gruppo Oncologico del Nord-Ovest 238
Testing effectiveness (Phase 2)Ended earlyNCT05572684
What this trial is testing

A Safety, Tolerability and Efficacy Study of NC410 Plus Pembrolizumab in Participants With Advanced Unresectable or Metastatic Solid Tumors

Who this might be right for
Advanced or Metastatic Solid TumorsMicrosatellite Instability LowMicrosatellite Instability High+9 more
NextCure, Inc. 97
Testing effectiveness (Phase 2)Study completedNCT03164655
What this trial is testing

Improving SUrgery of Liver Metastases: a Trial of the Arterial Chemotherapy Network

Who this might be right for
Colorectal Cancer Metastatic
UNICANCER 20
Large-scale testing (Phase 3)Not Yet RecruitingNCT06446557
What this trial is testing

De-scalation or swItch of Treatment According to Circulating tuMOr DNA Variation After 2 Cycles of Doublet Chemotherapy Plus Targeted Agent in Metastatic Unresectable Colorectal Cancer

Who this might be right for
Metastatic Colon Cancer
University Hospital, Rouen 408
Large-scale testing (Phase 3)Study completedNCT00265824
What this trial is testing

Optimized Chemotherapy Followed by Maintenance With Bevacizumab With or Without Erlotinib in Treating Patients With Metastatic Colorectal Cancer That Cannot be Removed by Surgery (DREAM)

Who this might be right for
Colorectal Cancer
GERCOR - Multidisciplinary Oncology Cooperative Group 700
Large-scale testing (Phase 3)Not Yet RecruitingNCT06616259
What this trial is testing

First-line Treatment of MCapOX + Cetuximab Vs. MFOLFOX6 + Cetuximab for RAS/BRAF Wild-type, MSS, Unresectable Left-Sided MCRC: a Multicenter, Randomized, Controlled, Phase III Study

Who this might be right for
Colorectal Cancer (CRC)CapecitabineCetuximab
Meng Qiu 452
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