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Results for “Unresectable Stage IIIB-IV Malignant Melanoma”

45 trials

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Showing 20 of 45 results

Early research (Phase 1)Study completedNCT03229278
What this trial is testing

Trigriluzole With Nivolumab and Pembrolizumab in Treating Patients With Metastatic or Unresectable Solid Malignancies or Lymphoma

Who this might be right for
LymphomaMetastatic Malignant Solid NeoplasmMetastatic Melanoma+26 more
Rutgers, The State University of New Jersey 14
Early research (Phase 1)Ended earlyNCT02097225
What this trial is testing

Onalespib, Dabrafenib, and Trametinib in Treating Patients With BRAF-Mutant Melanoma or Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery

Who this might be right for
BRAF V600E Mutation PresentBRAF V600K Mutation PresentMetastatic Malignant Solid Neoplasm+7 more
National Cancer Institute (NCI) 22
Testing effectiveness (Phase 2)Active Not RecruitingNCT03719131
What this trial is testing

Rituximab and Hyaluronidase Human in Patients With Advanced Melanoma Undergoing Nivolumab and Ipilimumab Therapy

Who this might be right for
Cutaneous Melanoma, Stage IIICutaneous Melanoma, Stage IVStage III Melanoma+5 more
Emory University 15
Early research (Phase 1)Study completedNCT01496807
What this trial is testing

Yervoy With Sylatron Unresectable Stage 3 or 4 Melanoma

Who this might be right for
Melanoma
H. Lee Moffitt Cancer Center and Research Institute 31
Large-scale testing (Phase 3)Study completedNCT00110019
What this trial is testing

Carboplatin and Paclitaxel With or Without Sorafenib Tosylate in Treating Patients With Stage III or Stage IV Melanoma That Cannot Be Removed by Surgery

Who this might be right for
Mucosal MelanomaRecurrent MelanomaStage IIIA Skin Melanoma+3 more
National Cancer Institute (NCI) 823
Testing effectiveness (Phase 2)Active Not RecruitingNCT02965716
What this trial is testing

Talimogene Laherparepvec and Pembrolizumab in Treating Patients With Stage III-IV Melanoma

Who this might be right for
Advanced MelanomaRecurrent MelanomaStage III Cutaneous Melanoma AJCC v7+5 more
National Cancer Institute (NCI) 43
Testing effectiveness (Phase 2)Study completedNCT00003989
What this trial is testing

ISIS 3521 in Treating Patients With Advanced, Unresectable, or Metastatic Non-small Cell Lung Cancer or Unresectable or Metastatic Melanoma

Who this might be right for
Lung CancerMelanoma (Skin)
European Organisation for Research and Treatment of Cancer - EORTC 50
Testing effectiveness (Phase 2)Study completedNCT02304458
What this trial is testing

Nivolumab With or Without Ipilimumab in Treating Younger Patients With Recurrent or Refractory Solid Tumors or Sarcomas

Who this might be right for
Metastatic MelanomaRecurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal TumorRecurrent Hodgkin Lymphoma+20 more
National Cancer Institute (NCI) 140
Testing effectiveness (Phase 2)UnknownNCT04200040
What this trial is testing

A Clinical Study to Evaluate the Safety and Efficacy of OrienX010 in Unresectable Malignant Melanoma Patients

Who this might be right for
Melanoma (Skin)
OrienGene Biotechnology Ltd. 165
Large-scale testing (Phase 3)Study completedNCT02714218
What this trial is testing

Two Different Dose Combinations of Nivolumab in Combination With Ipilimumab in Subjects With Previously Untreated, Unresectable or Metastatic Melanoma

Who this might be right for
Melanoma
Bristol-Myers Squibb 387
Early research (Phase 1)Study completedNCT03021460
What this trial is testing

Pembrolizumab and Ibrutinib in Treating Patients With Stage III-IV Melanoma That Cannot Be Removed by Surgery

Who this might be right for
Metastatic MelanomaStage III Cutaneous Melanoma AJCC v7Stage IIIA Cutaneous Melanoma AJCC v7+4 more
Mayo Clinic 20
Testing effectiveness (Phase 2)Active Not RecruitingNCT04940299
What this trial is testing

Tocilizumab, Ipilimumab, and Nivolumab for the Treatment of Advanced Melanoma, Non-Small Cell Lung Cancer, or Urothelial Carcinoma

Who this might be right for
Clinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8Locally Advanced Bladder Carcinoma+39 more
M.D. Anderson Cancer Center 35
Testing effectiveness (Phase 2)Study completedNCT02272855
What this trial is testing

Combination Treatment With HF10 and Ipilimumab in Patients With Unresectable or Metastatic Melanoma

Who this might be right for
Malignant Melanoma
Takara Bio Inc. 46
Testing effectiveness (Phase 2)Active Not RecruitingNCT04462406
What this trial is testing

Using Biomarkers to Help Guide Safe Immunotherapy Discontinuation in Patients With Unresectable Stage IIIB-IV Melanoma, The PET-Stop Trial

Who this might be right for
Advanced MelanomaClinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8+8 more
ECOG-ACRIN Cancer Research Group 150
Testing effectiveness (Phase 2)Ended earlyNCT02748564
What this trial is testing

Aldesleukin and Pembrolizumab in Treating Patients With Stage III-IV Melanoma

Who this might be right for
Metastatic MelanomaStage III Mucosal Melanoma of the Head and NeckStage IIIA Skin Melanoma+6 more
Rutgers, The State University of New Jersey 10
Early research (Phase 1)Study completedNCT01176461
What this trial is testing

Multiple Class I Peptides & Montanide ISA 51 VG w Escalating Doses of Anti-PD-1 ab BMS936558

Who this might be right for
Melanoma (Skin)
H. Lee Moffitt Cancer Center and Research Institute 127
Early research (Phase 1)Active Not RecruitingNCT03816332
What this trial is testing

Tacrolimus, Nivolumab, and Ipilimumab in Treating Kidney Transplant Recipients With Selected Unresectable or Metastatic Cancers

Who this might be right for
Clinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage III Cutaneous Merkel Cell Carcinoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8+18 more
National Cancer Institute (NCI) 12
Early research (Phase 1)Ended earlyNCT02419495
What this trial is testing

Phase IB Study to Evaluate the Safety of Selinexor (KPT-330) in Combination With Multiple Standard Chemotherapy or Immunotherapy Agents in Patients With Advanced Malignancies

Who this might be right for
Advanced Malignant Solid NeoplasmClinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8+26 more
M.D. Anderson Cancer Center 221
Testing effectiveness (Phase 2)Active Not RecruitingNCT03767348
What this trial is testing

Study of RP1 Monotherapy and RP1 in Combination With Nivolumab (IGNYTE)

Who this might be right for
Non-Small Cell Lung Cancer (NSCLC)Microsatellite Instability-High (MSI-H)Non-melanoma Skin Cancer (NMSC)+1 more
Replimune, Inc. 340
Testing effectiveness (Phase 2)Ended earlyNCT06984328
What this trial is testing

Study of the Effectiveness and Safety of Acasunlimab Alone and With Pembrolizumab to Treat Advanced Melanoma of the Skin That Has Returned After Treatment With an Approved Checkpoint Inhibitor Therapy (ABBIL1TY MELANOMA-07)

Who this might be right for
Cutaneous MelanomaRelapsed/Refractory, Locally Advanced Unresectable Melanoma (Stage IIIB, IIIC, or IIID)Metastatic Cutaneous Melanoma (Stage IV)
Genmab 1
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