Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Urea Cycle Disorders”

113 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 113 results

Testing effectiveness (Phase 2)Study completedNCT03378531
What this trial is testing

AEB1102 (Pegzilarginase) in Patients With Arginase I Deficiency

Who this might be right for
Arginase I DeficiencyHyperargininemia
Aeglea Biotherapeutics 14
Testing effectiveness (Phase 2)WithdrawnNCT01791192
What this trial is testing

Study of FTY720 in Patients With Uveitis

Who this might be right for
Acute Noninfectious Posterior, Intermediate, or Pan Uveitis
Novartis Pharmaceuticals
Post-approval studies (Phase 4)Study completedNCT02246218
What this trial is testing

The Safety, Efficacy and Pharmacokinetics of Glycerol Phenylbutyrate in Pediatric Subjects Under 2 Years of Age With Urea Cycle Disorders

Who this might be right for
Urea Cycle Disorder
Amgen 27
Not applicableLooking for participantsNCT00237315
What this trial is testing

Longitudinal Study of Urea Cycle Disorders

Who this might be right for
Brain Diseases, Metabolic, InbornAmino Acid Metabolism, Inborn ErrorsUrea Cycle Disorders
Andrea Gropman 1,500
Not applicableStudy completedNCT05706714
What this trial is testing

Th1, Th2, Th17 Phenotype in Urea Cycle Disorders

Who this might be right for
Urea Cycle DisorderLysinuric Protein Intolerance
Istanbul University - Cerrahpasa 65
Testing effectiveness (Phase 2)WithdrawnNCT03767270
What this trial is testing

Safety, Tolerability and PK/PD Evaluation of Intravenous Administration of MRT5201 in Patients With OTC Deficiency

Who this might be right for
Ornithine Transcarbamylase Deficiency
Translate Bio, Inc.
Large-scale testing (Phase 3)Study completedNCT06582524
What this trial is testing

Pegzilarginase in Subjects <24 Months Old With Arginase 1 Deficiency

Who this might be right for
Arginase 1 Deficiency
Immedica Pharma AB 3
Not applicableEnrolling By InvitationNCT03655223
What this trial is testing

Early Check: Expanded Screening in Newborns

Who this might be right for
Spinal Muscular AtrophyFragile X SyndromeFragile X - Premutation+182 more
RTI International 30,000
Large-scale testing (Phase 3)UnknownNCT01824030
What this trial is testing

FFR or OCT Guidance to RevasculariZe Intermediate Coronary Stenosis Using Angioplasty

Who this might be right for
Ischemic Heart Disease
Catholic University of the Sacred Heart 400
Not applicableLooking for participantsNCT07573059
What this trial is testing

Evaluation of the Safety of Loargys Arginine Test System in Loargys-treated Patients

Who this might be right for
ARG1 Deficiency
Immedica Pharma US Inc 100
Not applicableStudy completedNCT04248062
What this trial is testing

Patient and Observer Reported Outcome Measurements in Inborn Errors of Metabolism

Who this might be right for
Inborn Errors of MetabolismUrea Cycle DisorderMaple Syrup Urine Disease+5 more
University Children's Hospital, Zurich 69
Not applicableStudy completedNCT01610089
What this trial is testing

Nitric Oxide Flux and Ureagenesis in Argininosuccinate Synthetase Deficiency (ASSD)(Citrullinemia I)

Who this might be right for
Citrullinemia
Baylor College of Medicine 6
Testing effectiveness (Phase 2)Looking for participantsNCT06255782
What this trial is testing

An Open-label Study to Investigate ECUR-506 in Male Babies Less Than 9 Months of Age With Neonatal Onset OTC Deficiency

Who this might be right for
Ornithine Transcarbamylase DeficiencyOrnithine Transcarbamylase Deficiency DiseaseOrnithine Carbamoyltransferase Deficiency (Disorder)+1 more
iECURE, Inc. 20
Not applicableLooking for participantsNCT02935283
What this trial is testing

Neuroimaging and Neuropsychological Outcomes in Urea Cycle Disorders

Who this might be right for
Urea Cycle Disorders
Children's National Research Institute 56
Testing effectiveness (Phase 2)WithdrawnNCT03884959
What this trial is testing

A Safety and Efficacy Study of Infusions of HepaStem in Urea Cycle Disorders Pediatric Patients

Who this might be right for
Urea Cycle Disorder
HLB Cell Co., Ltd.
Early research (Phase 1)Ended earlyNCT00004386
What this trial is testing

Phase I Pilot Study of Liver-Directed Gene Therapy for Partial Ornithine Transcarbamylase Deficiency

Who this might be right for
Ornithine Transcarbamylase Deficiency Disease
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Not applicableEnded earlyNCT03343756
What this trial is testing

HepaStem Long-Term Safety Registry

Who this might be right for
Urea Cycle DisorderCrigler-Najjar SyndromeAcute on Chronic Liver Failure
Cellaion SA 44
Early research (Phase 1)UnknownNCT00004307
What this trial is testing

Study of Treatment and Metabolism in Patients With Urea Cycle Disorders

Who this might be right for
Amino Acid Metabolism, Inborn Errors
National Center for Research Resources (NCRR) 66
Not applicableNot Yet RecruitingNCT06664840
What this trial is testing

MyRareDiet A Novel Diet Tracking Tool

Who this might be right for
Urea Cycle DisorderPropionic AciduriaMaple Syrup Urine Disease+1 more
Oregon Health and Science University 60
Early research (Phase 1)Study completedNCT03179878
What this trial is testing

Safety and Tolerability of SYNB1020-CP-001

Who this might be right for
Healthy VolunteerUrea Cycle Disorder
Synlogic 52
Load More Results