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Results for “Urea Cycle Disorders, Inborn”

109 trials

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Showing 20 of 109 results

Large-scale testing (Phase 3)Study completedNCT06431113
What this trial is testing

Effect of Fixed Combination Citicoline Homotaurine and Pyrroloquinoline Quinone on Pattern-electroretinogram in Glaucoma

Who this might be right for
GlaucomaNeuroprotection
Fondazione IRCCS Policlinico San Matteo di Pavia 40
Testing effectiveness (Phase 2)Study completedNCT00004767
What this trial is testing

Phase II Study of Sodium Phenylbutyrate, Sodium Benzoate, Sodium Phenylacetate, and Dietary Intervention for Urea Cycle Disorders

Who this might be right for
Amino Acid Metabolism, Inborn Errors
National Center for Research Resources (NCRR) 20
Not applicableStudy completedNCT02740153
What this trial is testing

PCORI Urea Cycle Disorder Study

Who this might be right for
Urea Cycle Disorders
Children's National Research Institute 187
Not applicableEnded earlyNCT01541722
What this trial is testing

Oxidative Stress, Inflammation and Acute Decompensation in Urea Cycle Disorders

Who this might be right for
Urea Cycle Disorders
Mark Batshaw 10
Testing effectiveness (Phase 2)Study completedNCT03378531
What this trial is testing

AEB1102 (Pegzilarginase) in Patients With Arginase I Deficiency

Who this might be right for
Arginase I DeficiencyHyperargininemia
Aeglea Biotherapeutics 14
Post-approval studies (Phase 4)Study completedNCT01257737
What this trial is testing

To Evaluate the Safety of Long-term Use of HPN-100 in the Management of Urea Cycle Disorders (UCDs)

Who this might be right for
Urea Cycle Disorders
Amgen 88
Testing effectiveness (Phase 2)Ended earlyNCT01195753
What this trial is testing

Human Heterologous Liver Cells for Infusion in Children With Urea Cycle Disorders

Who this might be right for
Urea Cycle Disorders
Cytonet GmbH & Co. KG 10
Not applicableStudy completedNCT04444037
What this trial is testing

Impact of OCT Imaging on Decision Making During PCI in ACS Patients

Who this might be right for
Acute Coronary Syndrome
Assiut University 390
Testing effectiveness (Phase 2)Study completedNCT00551200
What this trial is testing

Dose-Escalation Safety Study of HPN-100 to Treat Urea Cycle Disorders

Who this might be right for
Urea Cycle Disorders
Amgen 14
Not applicableEnrolling By InvitationNCT06953505
What this trial is testing

At Home Ammonia Monitoring of Inborn Errors of Ammonia Metabolism

Who this might be right for
Urea Cycle DisordersOrganic AcidemiasFatty Acid Oxidation Disorder+1 more
Sequitur Health Corp. 30
Not applicableStudy completedNCT03064048
What this trial is testing

Nitric Oxide Supplementation on Neurocognitive Functions in Patients With ASLD

Who this might be right for
Argininosuccinate Lyase DeficiencyUrea Cycle DisorderUrea Cycle Disorders, Inborn+1 more
Baylor College of Medicine 16
Testing effectiveness (Phase 2)Study completedNCT02488044
What this trial is testing

AEB1102 in Patients With Arginase I Deficiency

Who this might be right for
Arginase I DeficiencyHyperargininemia
Aeglea Biotherapeutics 16
Testing effectiveness (Phase 2)WithdrawnNCT03767270
What this trial is testing

Safety, Tolerability and PK/PD Evaluation of Intravenous Administration of MRT5201 in Patients With OTC Deficiency

Who this might be right for
Ornithine Transcarbamylase Deficiency
Translate Bio, Inc.
Not applicableStudy completedNCT01663896
What this trial is testing

Observational Study of OCT in a Patients Undergoing FFR

Who this might be right for
Coronary Artery Disease
Abbott Medical Devices 418
Not applicableEnded earlyNCT04909346
What this trial is testing

Adeno-Associated Virus (AAV) Antibody Study in Subjects OTC Deficiency, GSDIa, and Wilson Disease

Who this might be right for
Ornithine Transcarbamylase DeficiencyWilson DiseaseGlycogen Storage Disease Type IA
Ultragenyx Pharmaceutical Inc 51
Testing effectiveness (Phase 2)Ended earlyNCT05526066
What this trial is testing

Study for Adolescents and Adults With Ornithine Transcarbamylase Deficiency to Evaluate Safety and Tolerability of ARCT-810

Who this might be right for
Ornithine Transcarbamylase DeficiencyOTC DeficiencyOTCD
Arcturus Therapeutics, Inc. 8
Early research (Phase 1)Looking for participantsNCT06247670
What this trial is testing

Study of CMP-CPS-001 in Healthy Volunteers

Who this might be right for
Healthy Volunteers
CAMP4 Therapeutics Corporation 96
Early research (Phase 1)Study completedNCT00986895
What this trial is testing

Glyceryl Tri-(4-phenylbutyrate) Administered Orally as a Single Dose, and Twice Daily for Seven Consecutive Days to Subjects With Hepatic Impairment With Cirrhosis and to a Control Group

Who this might be right for
Hepatic EncephalopathyUrea Cycle Disorders
Amgen 32
Not applicableLooking for participantsNCT06805695
What this trial is testing

Long-term Follow-up (LTFU) Study of Participants in Any iECURE Protocol Using an Investigational Product (IP)

Who this might be right for
Ornithine Transcarbamylase DeficiencyOrnithine Transcarbamylase Deficiency DiseaseUrea Cycle Disorders, Inborn
iECURE, Inc. 13
Not applicableStudy completedNCT05388357
What this trial is testing

AI Quantitative Coronary Angiography Versus Optical Coherent Tomography Guidance for Coronary Stent Implantation

Who this might be right for
Coronary VesselsProcedure PCI
Asan Medical Center 400
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