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Results for “Urea Cycle Disorders, Inborn”

114 trials

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Showing 20 of 114 results

Large-scale testing (Phase 3)Study completedNCT06431113
What this trial is testing

Effect of Fixed Combination Citicoline Homotaurine and Pyrroloquinoline Quinone on Pattern-electroretinogram in Glaucoma

Who this might be right for
GlaucomaNeuroprotection
Fondazione IRCCS Policlinico San Matteo di Pavia 40
Large-scale testing (Phase 3)Study completedNCT01347073
What this trial is testing

Study of the Safety, Pharmacokinetics and Efficacy of HPN-100, in Pediatric Subjects With Urea Cycle Disorders (UCDs)

Who this might be right for
Urea Cycle Disorders
Amgen 23
Testing effectiveness (Phase 2)Study completedNCT02991144
What this trial is testing

Safety and Dose-Finding Study of DTX301 (scAAV8OTC) in Adults With Late-Onset Ornithine Transcarbamylase (OTC) Deficiency

Who this might be right for
Ornithine Transcarbamylase (OTC) Deficiency
Ultragenyx Pharmaceutical Inc 16
Not applicableStudy completedNCT06845397
What this trial is testing

Chuvashia Inappropriate Prescribing Study

Who this might be right for
Multimorbidity, Cardiovascular Diseases
National Medical Research Center for Therapy and Preventive Medicine 300
Not applicableUnknownNCT02935283
What this trial is testing

Neuroimaging and Neuropsychological Outcomes in Urea Cycle Disorders

Who this might be right for
Urea Cycle Disorders
Children's National Research Institute 56
Early research (Phase 1)Study completedNCT04442347
What this trial is testing

Phase 1b Study to Assess Safety, Tolerability, and Pharmacokinetics of ARCT-810 in Stable Adult Subjects With Ornithine Transcarbamylase Deficiency

Who this might be right for
Ornithine Transcarbamylase Deficiency
Arcturus Therapeutics, Inc. 16
Not applicableStudy completedNCT01389947
What this trial is testing

Microcirculation During Extracorporeal Circulation

Who this might be right for
Mesenteric Ischemia
Centre Hospitalier Universitaire de Besancon 66
Not applicableStudy completedNCT03911089
What this trial is testing

A Collection of Case Studies in Infants With UCD to Evaluate Infant Growth and the Safety of a New Medical Food for UCD

Who this might be right for
Urea Cycle DisorderInborn Errors of Metabolism
Nutricia Research 3
Testing effectiveness (Phase 2)Looking for participantsNCT06488313
What this trial is testing

Evaluate the Pharmacodynamics and Safety of ARCT-810 in Participants With OTCD

Who this might be right for
OTC DeficiencyOrnithine Transcarbamylase DeficiencyOTCD
Arcturus Therapeutics, Inc. 9
Not applicableStudy completedNCT01569568
What this trial is testing

Investigation of Brain Nitrogen in Partial Ornithine Transcarbamylase Deficiency (OTCD) Using 1 H MRS, DTI, and fMRI

Who this might be right for
Ornithine Transcarbamylase Deficiency
Andrea Gropman 49
Testing effectiveness (Phase 2)Ended earlyNCT05526066
What this trial is testing

Study for Adolescents and Adults With Ornithine Transcarbamylase Deficiency to Evaluate Safety and Tolerability of ARCT-810

Who this might be right for
Ornithine Transcarbamylase DeficiencyOTC DeficiencyOTCD
Arcturus Therapeutics, Inc. 8
Not applicableLooking for participantsNCT02132741
What this trial is testing

Optical Coherence Tomography And NEphropathy: The OCTANE Study

Who this might be right for
HealthHypertensionChronic Kidney Disease
University of Edinburgh 150
Not applicableLooking for participantsNCT06805695
What this trial is testing

Long-term Follow-up (LTFU) Study of Participants in Any iECURE Protocol Using an Investigational Product (IP)

Who this might be right for
Ornithine Transcarbamylase DeficiencyOrnithine Transcarbamylase Deficiency DiseaseUrea Cycle Disorders, Inborn
iECURE, Inc. 13
Large-scale testing (Phase 3)Study completedNCT06582524
What this trial is testing

Pegzilarginase in Subjects <24 Months Old With Arginase 1 Deficiency

Who this might be right for
Arginase 1 Deficiency
Immedica Pharma AB 3
Large-scale testing (Phase 3)Study completedNCT00947297
What this trial is testing

Study of the Safety of HPN (Hyperion)-100 for the Long-Term Treatment of Urea Cycle Disorders (Treat UCD)

Who this might be right for
Urea Cycle Disorders
Amgen 60
Not applicableStudy completedNCT01080859
What this trial is testing

Vessel Wall Response of the Bio-Active-stent and Everolimus-Eluting Stent Assessed By Optical Coherence Tomography

Who this might be right for
Acute Coronary Syndrome
The Hospital District of Satakunta 40
Not applicableLooking for participantsNCT06904027
What this trial is testing

A Clinical Study of Glycerol Phenylbutyrate in Chinese Patients With Urea Cycle Disorders

Who this might be right for
Urea Cycle Disorders
Tongji Hospital 40
Testing effectiveness (Phase 2)Study completedNCT01599286
What this trial is testing

Short-Term Outcome of N-Carbamylglutamate in the Treatment of Acute Hyperammonemia

Who this might be right for
Propionic Acidemia, Type I and/or Type IIMethylmalonic AcidemiaCarbamoyl-Phosphate Synthase I Deficiency Disease+1 more
Mendel Tuchman 35
Not applicableNot Yet RecruitingNCT07241845
What this trial is testing

Epiretinal Membrane in Patients With DR.

Who this might be right for
Epiretinal Membrane
Assiut University 225
Not applicableStudy completedNCT03064048
What this trial is testing

Nitric Oxide Supplementation on Neurocognitive Functions in Patients With ASLD

Who this might be right for
Argininosuccinate Lyase DeficiencyUrea Cycle DisorderUrea Cycle Disorders, Inborn+1 more
Baylor College of Medicine 16
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