Not applicableEnded earlyNCT03753854What this trial is testingSleep Apnea in Sickle Cell DiseaseWho this might be right forSickle Cell Disease Hospices Civils de Lyon 30
Large-scale testing (Phase 3)UnknownNCT05289700What this trial is testingHyperbaric-oxygen Therapy (HBOT) Versus Placebo for Treating Vaso-Occlusive Crisis (VOC) in Sickle Cell Disease (SCD)Who this might be right forSickle Cell DiseaseHyperbaric Oxygen TherapyVaso-occlusive Crisis University Hospital, Geneva 100
Not applicableStudy completedNCT05572294What this trial is testingMindfulness and Yoga Therapy for Acute Pain in Sickle Cell DiseaseWho this might be right forSickle Cell CrisisSickle Cell Disease University of Texas Southwestern Medical Center 39
Large-scale testing (Phase 3)Ended earlyNCT02433158What this trial is testingSafety of Rivipansel (GMI-1070) in the Treatment of One or More Vaso-Occlusive Crises in Hospitalized Subjects With Sickle Cell DiseaseWho this might be right forSickle Cell AnemiaSickle Cell DiseaseSickle Cell Disorders+2 more GlycoMimetics Incorporated 154
Post-approval studies (Phase 4)Study completedNCT02434939What this trial is testingLow-dose Ketamine vs Morphine for Vaso-occlusive Crisis in SicklersWho this might be right forSickle Cell CrisisAcute Pain Makerere University 240
Post-approval studies (Phase 4)Study completedNCT04662931What this trial is testingAn Indian Multi-centric Phase IV Study to Assess the Safety of Crizanlizumab in Sickle Cell Disease PatientsWho this might be right forSickle Cell Disease (SCD) Novartis Pharmaceuticals 140
Large-scale testing (Phase 3)Active Not RecruitingNCT03814746What this trial is testingStudy of Two Doses of Crizanlizumab Versus Placebo in Adolescent and Adult Sickle Cell Disease PatientsWho this might be right forSickle Cell Disease (SCD) Novartis Pharmaceuticals 254
Testing effectiveness (Phase 2)Study completedNCT01119833What this trial is testingStudy of GMI-1070 for the Treatment of Sickle Cell Pain CrisisWho this might be right forSickle Cell DiseaseVaso-occlusive CrisisPain Crisis GlycoMimetics Incorporated 81
Not applicableStudy completedNCT00004797What this trial is testingPilot Study of Fructose for Sickle Cell CrisisWho this might be right forSickle Cell Anemia National Center for Research Resources (NCRR) 20
Testing effectiveness (Phase 2)Study completedNCT00434473What this trial is testingIMPACTS Trial: Investigation of the Modulation of Phospholipase in Acute Chest SyndromeWho this might be right forSickle Cell DiseaseVaso-occlusive CrisisAcute Chest Syndrome Anthera Pharmaceuticals 30
Post-approval studies (Phase 4)Study completedNCT02222246What this trial is testingComparing Acute Pain Management Protocols for Patients With Sickle Cell DiseaseWho this might be right forSickle Cell Disease Duke University 106
Not applicableLooking for participantsNCT07246265What this trial is testingMorphine Clearance and Glomerular Filtration in Sickle Cell Patients in Crisis in Intensive CareWho this might be right forSickle Cell DiseaseGlomerular HyperfiltrationSickle Cell Nephropathy+2 more University Hospital, Tours 100
Large-scale testing (Phase 3)Study completedNCT00004408What this trial is testingPhase III Randomized Study of Poloxamer 188 for Vaso-Occlusive Crisis of Sickle Cell DiseaseWho this might be right forSickle Cell Anemia Mast Therapeutics, Inc. 300
Testing effectiveness (Phase 2)Looking for participantsNCT06635902What this trial is testingIntravenous L-Citrulline for Vaso-occlusive Pain Episode in Sickle Cell DiseaseWho this might be right forSickle Cell DiseaseVaso-occlusive Pain Episode Suvankar Majumdar 99
Testing effectiveness (Phase 2)UnknownNCT03062501What this trial is testingHydroxyurea in the Emergency Room to Lessen Pain in Sickle Cell CrisisWho this might be right forAnemia, Sickle CellAnemia; Sickle-Cell, With Crisis Instituto Estadual de Hematologia Arthur de Siqueira Cavalcanti 30
Testing effectiveness (Phase 2)Study completedNCT01419977What this trial is testingTreatment of Sickle Cell Patients Hospitalized in Pain Crisis With Prophylactic Dose Low-molecular-weight Heparin (LMWH) Versus PlaceboWho this might be right forSickle Cell DiseaseVaso-occlusive Crisis Duke University 34
Not applicableLooking for participantsNCT07188766What this trial is testingEfficacy of Liberal Versus Restricted IV Fluid Approach in the Management of Sickle Cell Vaso-Occlusive CrisisWho this might be right forSCDVaso Occlussive Crisis Imam Abdulrahman Bin Faisal University 394
Large-scale testing (Phase 3)Ended earlyNCT03615924What this trial is testingEffect of Ticagrelor vs. Placebo in the Reduction of Vaso-occlusive Crises in Pediatric Patients With Sickle Cell DiseaseWho this might be right forSickle Cell Disease AstraZeneca 193
Post-approval studies (Phase 4)Not Yet RecruitingNCT07682662What this trial is testingLow Dose Bolus Ketamine For Use In Sickle Cell Pain CrisisWho this might be right forVaso-Occlusive Pain Episode in Sickle Cell DiseaseSickle Cell Disease (SCD) University of Mississippi Medical Center 400
Large-scale testing (Phase 3)Looking for participantsNCT07274254What this trial is testingLidocaine for Opioid Sparing in Vaso-occlusive Crisis of Sickle Cell DiseaseWho this might be right forVaso-Occlusive Pain Episode in Sickle Cell Disease Nantes University Hospital 104