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Results for “Vaso-occlusive Crisis”

129 trials

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Showing 20 of 129 results

Testing effectiveness (Phase 2)Looking for participantsNCT06399107
What this trial is testing

Investigation Into the Use of BAH243 Lentiviral Vector for Gene Therapy in Treating Sickle Cell Disease

Who this might be right for
Sickle Cell DiseaseSickle-Cell Disease With Crisis
Essen Biotech 85
Testing effectiveness (Phase 2)Study completedNCT01119833
What this trial is testing

Study of GMI-1070 for the Treatment of Sickle Cell Pain Crisis

Who this might be right for
Sickle Cell DiseaseVaso-occlusive CrisisPain Crisis
GlycoMimetics Incorporated 81
Post-approval studies (Phase 4)WithdrawnNCT04005209
What this trial is testing

Ketamine Infusion for Sickle Cell Pain Crisis

Who this might be right for
Anemia; Sickle-Cell, With CrisisAcute Pain
Duke University
Large-scale testing (Phase 3)Ended earlyNCT02179177
What this trial is testing

Apixaban in Patients With Sickle Cell Disease

Who this might be right for
Vaso-occlusive CrisisReduction in HospitalizationsSickle Cell Disease
Nirmish Shah 16
Not applicableStudy completedNCT03977532
What this trial is testing

Study of a Red Blood Cell Deformability Parameter in Patients With Sickle Cell Disease

Who this might be right for
Sickle Cell Disease
Assistance Publique Hopitaux De Marseille 21
Large-scale testing (Phase 3)Ended earlyNCT03615924
What this trial is testing

Effect of Ticagrelor vs. Placebo in the Reduction of Vaso-occlusive Crises in Pediatric Patients With Sickle Cell Disease

Who this might be right for
Sickle Cell Disease
AstraZeneca 193
Not applicableStudy completedNCT06650059
What this trial is testing

Cohort Study of Sickle Cell Patients Evaluating Analgesic Strategies and Their Consequences

Who this might be right for
Sickle Cell Disease
Assistance Publique - Hôpitaux de Paris 257
Testing effectiveness (Phase 2)Study completedNCT03474965
What this trial is testing

Study of Dose Confirmation and Safety of Crizanlizumab in Pediatric Sickle Cell Disease Patients

Who this might be right for
Sickle Cell Disease (SCD)
Novartis Pharmaceuticals 117
Testing effectiveness (Phase 2)Study completedNCT02411708
What this trial is testing

Study of SANGUINATE™ In the Treatment of Sickle Cell Disease Patients With Vaso-Occlusive Crisis

Who this might be right for
Anemia, Sickle Cell
Prolong Pharmaceuticals 24
Not applicableEnded earlyNCT01501643
What this trial is testing

Non Invasive Positive Pressure Ventilation for Prevention of Acute Chest Syndrome in Sickle Cell Disease

Who this might be right for
Sickle Cell-hemoglobin SS DiseaseVaso-occlusive Crisis
Assistance Publique - Hôpitaux de Paris 6
Not applicableUnknownNCT05388188
What this trial is testing

DSUVIA in Patients With SCD VOC Present in the ED

Who this might be right for
Sickle-Cell Disease With Crisis
Jason Wilson 100
Post-approval studies (Phase 4)Not Yet RecruitingNCT06579703
What this trial is testing

Ketorolac for Acute Vaso-Occlusive Crisis in Pediatric Sickle Cell Disease

Who this might be right for
Sickle Cell DiseaseSickle Cell CrisisVeno-occlusive Disease
Children's Blood and Cancer Center at Dell Children's Medical Center 102
Testing effectiveness (Phase 2)Study completedNCT00513617
What this trial is testing

Effectiveness of Arginine as a Treatment for Sickle Cell Anemia

Who this might be right for
Anemia, Sickle Cell
UCSF Benioff Children's Hospital Oakland 128
Not applicableStudy completedNCT04756375
What this trial is testing

Evaluation of Virtual Reality to Save Morphinic in the Treatment of Vaso-occlusive Seizures of Sickle Cell Patients Consulting in the Emergency Room

Who this might be right for
Vaso-occlusive CrisisSickle Cell Disease
Assistance Publique - Hôpitaux de Paris 97
Testing effectiveness (Phase 2)Study completedNCT01895361
What this trial is testing

Study to Assess Safety and Impact of SelG1 With or Without Hydroxyurea Therapy in Sickle Cell Disease Patients With Pain Crises

Who this might be right for
Sickle Cell Disease
Reprixys Pharmaceutical Corporation 198
Testing effectiveness (Phase 2)Study completedNCT05075824
What this trial is testing

A Study Evaluating the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Crovalimab as Adjunct Treatment in Prevention of Vaso-Occlusive Episodes (VOE) in Sickle Cell Disease (SCD)

Who this might be right for
Sickle Cell Disease
Hoffmann-La Roche 95
Testing effectiveness (Phase 2)Looking for participantsNCT06635902
What this trial is testing

Intravenous L-Citrulline for Vaso-occlusive Pain Episode in Sickle Cell Disease

Who this might be right for
Sickle Cell DiseaseVaso-occlusive Pain Episode
Suvankar Majumdar 99
Post-approval studies (Phase 4)Study completedNCT02434939
What this trial is testing

Low-dose Ketamine vs Morphine for Vaso-occlusive Crisis in Sicklers

Who this might be right for
Sickle Cell CrisisAcute Pain
Makerere University 240
Early research (Phase 1)Study completedNCT04912869
What this trial is testing

A Study Evaluating the Safety, Pharmacokinetics, Pharmacodynamics and Efficacy of Crovalimab for the Management of Acute Uncomplicated Vaso-Occlusive Episodes (VOE) in Participants With Sickle Cell Disease (SCD).

Who this might be right for
Sickle Cell Disease
Hoffmann-La Roche 30
Large-scale testing (Phase 3)Study completedNCT05084521
What this trial is testing

Interest of Famotidine in Children With Sickle Cell Disease

Who this might be right for
Sickle Cell Disease
Assistance Publique - Hôpitaux de Paris 30
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