Not applicableStudy completedNCT00004797What this trial is testingPilot Study of Fructose for Sickle Cell CrisisWho this might be right forSickle Cell Anemia National Center for Research Resources (NCRR) 20
Testing effectiveness (Phase 2)Study completedNCT01895361What this trial is testingStudy to Assess Safety and Impact of SelG1 With or Without Hydroxyurea Therapy in Sickle Cell Disease Patients With Pain CrisesWho this might be right forSickle Cell Disease Reprixys Pharmaceutical Corporation 198
Large-scale testing (Phase 3)Not Yet RecruitingNCT06989567What this trial is testingIntravenous L-Citrulline in Patients Aged 6-21 Years Old With Sickle Cell Disease Presenting to Emergency Departments in Acute Vaso-Occlusive CrisisWho this might be right forSickle Cell Disease Asklepion Pharmaceuticals, LLC 120
Not applicableStudy completedNCT03977532What this trial is testingStudy of a Red Blood Cell Deformability Parameter in Patients With Sickle Cell DiseaseWho this might be right forSickle Cell Disease Assistance Publique Hopitaux De Marseille 21
Not applicableNot Yet RecruitingNCT06743113What this trial is testingHypoxic Red Blood Cells in Sickle Cell AnemiaWho this might be right forSickle Cell AnaemiaSickle Cell Anemia CrisisSickle Cell Anemia in Children+1 more Hemanext 48
Large-scale testing (Phase 3)Ended earlyNCT05348915What this trial is testingEvaluate the Long-term Safety of Inclacumab Administered to Participants With Sickle Cell DiseaseWho this might be right forSickle Cell DiseaseVaso-occlusive CrisisVaso-occlusive Pain Episode in Sickle Cell Disease Pfizer 242
Post-approval studies (Phase 4)UnknownNCT05848531What this trial is testingClonidine With Morphine in Patient Controlled Analgesia Pump in Vaso-Occlusive Crisis in Sickle Cell Disease PatientWho this might be right forSickle Cell DiseaseVaso-occlusive Pain Episode in Sickle Cell Disease Centre Hospitalier Universitaire Saint Pierre 40
Not applicableStudy completedNCT06345638What this trial is testingSex Hormones and Inflammatory Biomarkers in Patients With Sickle Cell DiseaseWho this might be right forSickle Cell DiseaseVaso-occlusive Crisis University of Pennsylvania 52
Not applicableStudy completedNCT03368924What this trial is testingImplication of the Oxydative Stress in the Pathophysiology of Sickle Cell Anemia:Who this might be right forSickle Cell Disease Centre Hospitalier Universitaire de la Guadeloupe 38
Not applicableEnded earlyNCT02698761What this trial is testingA Comprehensive Care Plan for Pediatric Patients With Vaso-Occlusive CrisesWho this might be right forSickle Cell DiseaseSickle Cell CrisisVaso-Occlusive Crises Valley Anesthesiology Consultants 3
Large-scale testing (Phase 3)Active Not RecruitingNCT04624659What this trial is testingEtavopivat in Adults and Adolescents With Sickle Cell Disease (HIBISCUS)Who this might be right forSickle Cell Disease Forma Therapeutics, Inc. 450
Not applicableNot Yet RecruitingNCT07782489What this trial is testingPleuropulmonary Ultrasound Imaging in Patients With Sickle Cell Disease in a Vaso-occlusive Crisis. "ECHODREP"Who this might be right forSickle Cell Disease (SCD)Vaso-Occlusive CrisesAcute Chest Syndrome Assistance Publique - Hôpitaux de Paris 200
Testing effectiveness (Phase 2)Study completedNCT01891812What this trial is testingNitrous Oxide Analgesia Vaso-occlusive CrisisWho this might be right forSickle Cell DiseaseVaso-occlusive Crisis Columbia University 5
Testing effectiveness (Phase 2)Ended earlyNCT01033227What this trial is testingSafety and Efficacy of Sodium Nitrite in Sickle Cell DiseaseWho this might be right forSickle Cell Disease Children's Hospital Los Angeles 5
Not applicableUnknownNCT05388188What this trial is testingDSUVIA in Patients With SCD VOC Present in the EDWho this might be right forSickle-Cell Disease With Crisis Jason Wilson 100
Testing effectiveness (Phase 2)Ended earlyNCT00532883What this trial is testingHydroxyurea and Magnesium Pidolate to Treat People With Hemoglobin Sickle Cell DiseaseWho this might be right forHemoglobin SC Disease St. Jude Children's Research Hospital 44
Large-scale testing (Phase 3)Study completedNCT05084521What this trial is testingInterest of Famotidine in Children With Sickle Cell DiseaseWho this might be right forSickle Cell Disease Assistance Publique - Hôpitaux de Paris 30
Post-approval studies (Phase 4)WithdrawnNCT04005209What this trial is testingKetamine Infusion for Sickle Cell Pain CrisisWho this might be right forAnemia; Sickle-Cell, With CrisisAcute Pain Duke University
Not applicableActive Not RecruitingNCT05780775What this trial is testingLipid Balance in Adult Sickle Cell PatientsWho this might be right forSickle Cell DiseaseDyslipidemiaComplication Centre Hospitalier Universitaire de la Guadeloupe 116
Testing effectiveness (Phase 2)Study completedNCT01119833What this trial is testingStudy of GMI-1070 for the Treatment of Sickle Cell Pain CrisisWho this might be right forSickle Cell DiseaseVaso-occlusive CrisisPain Crisis GlycoMimetics Incorporated 81