Early research (Phase 1)WithdrawnNCT04973618What this trial is testingStudy of APVO436 in Elderly or Unfit Patients With Newly Diagnosed AMLWho this might be right forAML Aptevo Therapeutics
Testing effectiveness (Phase 2)Ended earlyNCT04905407What this trial is testingTamibarotene Plus Venetoclax/Azacitidine in Participants With Newly Diagnosed Acute Myeloid Leukemia (AML)Who this might be right forAcute Myeloid Leukemia Syros Pharmaceuticals 66
Testing effectiveness (Phase 2)Active Not RecruitingNCT05833438What this trial is testingVenetoclax in Combination With 5 Days Azacitidine in Untreated AML Patients, Not Eligible for Standard Induction TherapyWho this might be right forAcute Myeloid Leukemia (AML) University of Leipzig 45
Testing effectiveness (Phase 2)Looking for participantsNCT07047183What this trial is testingClinical Study of Venetoclax Combined With Azacitidine as Bridging Therapy Prior to Hematopoietic Stem Cell Transplantation in Patients With Higher-Risk Myelodysplastic SyndromesWho this might be right forMyelodysplastic NeoplasmsTransplantation Yehui Tan 46
Testing effectiveness (Phase 2)Looking for participantsNCT04588922What this trial is testingStudy of SLS009 (Formerly GFH009) a Potent Highly Selective CDK9 Inhibitor in Patients With Hematologic Malignancies and High-Risk Newly Diagnosed AMLWho this might be right forHematologic Malignancies Sellas Life Sciences Group 160
Early research (Phase 1)Looking for participantsNCT06634394What this trial is testingAPVO436 Phase 1b/2 Study in Patients With Newly Diagnosed AMLWho this might be right forAcute Myeloid Leukemia (AML) Aptevo Therapeutics 39
Testing effectiveness (Phase 2)Looking for participantsNCT06394011What this trial is testingStudy of VA Combined With HAAG Regimen in Newly Diagnosed Intermediate and High-risk AML PatientsWho this might be right forIntermediate Risk Acute Myeloid LeukemiaHigh Risk Acute Myeloid Leukemia The First Affiliated Hospital of Soochow University 60
Testing effectiveness (Phase 2)Active Not RecruitingNCT04284787What this trial is testingBLAST MRD AML-2: BLockade of PD-1 Added to Standard Therapy to Target Measurable Residual Disease in Acute Myeloid Leukemia 2- A Randomized Phase 2 Study of Anti-PD-1 Pembrolizumab in Combination With Azacitidine and Venetoclax as Frontline Therapy in Unfit Patients With Acute Myeloid LeukemiaWho this might be right forAcute Myeloid LeukemiaAcute Myeloid Leukemia Arising From Previous Myelodysplastic SyndromeAcute Myeloid Leukemia Post Cytotoxic Therapy+1 more National Cancer Institute (NCI)
Testing effectiveness (Phase 2)Looking for participantsNCT06451861What this trial is testingRandomized Study of ABC-14 Regimen Compared With "3+7" Standard Induction Therapy or AB-14 for ND AMLWho this might be right forAcute Myeloid Leukemia Guangdong Provincial People's Hospital 240
Testing effectiveness (Phase 2)Ended earlyNCT04150029What this trial is testingMBG453 in Combination With Azacitidine and Venetoclax in AML Patients Unfit for ChemotherapyWho this might be right forAcute Myeloid Leukemia Novartis Pharmaceuticals 90
Testing effectiveness (Phase 2)Ended earlyNCT04160052What this trial is testingVenetoclax and Azacitidine for the Treatment of High-Risk Recurrent or Refractory Myelodysplastic SyndromeWho this might be right forChronic Myelomonocytic LeukemiaMyelodysplastic SyndromeRecurrent Myelodysplastic Syndrome+2 more M.D. Anderson Cancer Center 51
Large-scale testing (Phase 3)Ended earlyNCT05079230What this trial is testingStudy of Magrolimab Versus Placebo in Combination With Venetoclax and Azacitidine in Participants With Acute Myeloid LeukemiaWho this might be right forAcute Myeloid Leukemia Gilead Sciences 378
Early research (Phase 1)Looking for participantsNCT06419634What this trial is testingStudy of BMS-986497 (ORM-6151) as a Monotherapy, in Double and Triple Combination With Azacitidine and Venetoclax in Participants With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic SyndromeWho this might be right forAcute Myeloid LeukemiaMyelodysplastic Syndrome Bristol-Myers Squibb 105
Large-scale testing (Phase 3)Not Yet RecruitingNCT07082452What this trial is testingTrial Evaluating Efficacy and Safety of A Reduced Venetoclax Exposure To Seven Days Versus Standard Continuous Venetoclax Exposure Combined With Azacitidine in Treatment Naïve Subjects With Acute Myeloid Leukemia Who Are Ineligible for Intensive InductionWho this might be right forLeukemia, B-Cell, ChronicLeukemia Gustave Roussy, Cancer Campus, Grand Paris 262
Testing effectiveness (Phase 2)Ended earlyNCT04812548What this trial is testingSabatolimab in Combination With Azacitidine and Venetoclax in High or Very High Risk MDS ParticipantsWho this might be right forMyelodysplastic Syndrome (MDS) Novartis Pharmaceuticals 20
Testing effectiveness (Phase 2)Looking for participantsNCT06548230What this trial is testingA Phase 1B/2A Trial of NADUNOLIMAB in Combination With Azacitidine (With/Without Venetoclax) in Patients With Myelodysplastic Syndrome (MDS) and Acute Myelogenous Leukemia (AML)Who this might be right forMyelodysplastic Syndrome(MDS)Acute Myelogenous Leukemia (AML) M.D. Anderson Cancer Center 40
Large-scale testing (Phase 3)Looking for participantsNCT07007312What this trial is testingStudies to Assess Ziftomenib in Combination With Ven+Aza or 7+3 in Patients With Untreated NPM1-m or KMT2A-r AMLWho this might be right forAcute Myeloid Leukemia (AML) Kura Oncology, Inc. 1,300
Early research (Phase 1)Ended earlyNCT05107856What this trial is testingPRT1419 as Monotherapy or in Combination With Azacitidine or Venetoclax in R/R Myeloid or B-cell MalignanciesWho this might be right forAcute Myeloid LeukemiaB-cell Non-Hodgkin LymphomaChronic Lymphocytic Leukemia+7 more Prelude Therapeutics Incorporated 21
Early research (Phase 1)Temporarily pausedNCT06454409What this trial is testingRegorafenib in Combination With Venetoclax and Azacitidine for the Treatment of Patients With Relapsed or Refractory Acute Myeloid LeukemiaWho this might be right forMyelodysplastic Syndrome/Acute Myeloid LeukemiaRecurrent Acute Myeloid LeukemiaRecurrent Myelodysplastic Syndrome+2 more City of Hope Medical Center 20
Testing effectiveness (Phase 2)Study completedNCT04687761What this trial is testingClinical Trial to Assess the Safety and Tolerability of the Combination of Low-dose Cytarabine or Azacitidine Plus Venetoclax and Quizartinib in Newly Diagnosed AML Patients Aged Equal or More Than 60 Years OldWho this might be right forLeukemia, Myeloid, AcuteDe NovoAge More 60yr PETHEMA Foundation 113