Large-scale testing (Phase 3)Study completedNCT00000140What this trial is testingThe Silicone StudyWho this might be right forProliferative VitreoretinopathyRetinal Detachment National Eye Institute (NEI)
Large-scale testing (Phase 3)Study completedNCT04136366What this trial is testingThe GUARD Trial - Part 1: A Phase 3 Clinical Trial for Prevention of Proliferative VitreoretinopathyWho this might be right forProliferative Vitreoretinopathy Aldeyra Therapeutics, Inc. 106
Not applicableStudy completedNCT03208205What this trial is testingOutcomes of Vitrectomy in Pediatric Retinal Detachment With Proliferative VitreoretinopathyWho this might be right forPediatric Rhegmatogenous Retinal Detachment Medical University of Lublin 14
Testing effectiveness (Phase 2)Study completedNCT04891991What this trial is testingIntravitreal Infliximab for Proliferative VitreoretinopathyWho this might be right forRhegmatogenous Retinal DetachmentProliferative VitreoretinopathyRetinal Detachment Cairo University 66
Large-scale testing (Phase 3)WithdrawnNCT00403702What this trial is testingComparison High-density Silicone Oils in Retinal DetachmentWho this might be right forRetinal Detachment Asociación para Evitar la Ceguera en México
Not applicableStudy completedNCT05647928What this trial is testingRetinal Redetachment After Silicone Oil Removal : a Risk Factor AnalysisWho this might be right forRetinal Redetachment After Silicone Oil Removal Central Hospital, Nancy, France 307
Post-approval studies (Phase 4)Study completedNCT01995045What this trial is testingPostoperative Pain Control Following Vitreoretinal SurgeryWho this might be right forRetinal DetachmentProliferative VitreoretinopathyRetinoschisis Emory University 58
Not applicableStudy completedNCT04490876What this trial is testingOutcomes of Extensive Brilliant Blue G-Assisted Internal Limiting Membrane Peeling in Proliferative VitreoretinopathyWho this might be right forProliferative Vitreoretinopathy Centro Oftalmológico Dr Charles 14
Testing effectiveness (Phase 2)UnknownNCT04580147What this trial is testingIntravitreal Aflibercept for the Prevention of Proliferative Vitreoretinopathy Following Retinal Detachment RepairWho this might be right forRetinal Detachment With Multiple Breaks, Unspecified EyeProliferative Vitreoretinopathy M. Ali Khan, MD 150
Not applicableUnknownNCT05415826What this trial is testingOzurdex in Reducing PVR After Vitreotomy in PDRWho this might be right forDiabetic Retinopathy Peking University People's Hospital 30
Large-scale testing (Phase 3)Study completedNCT00373282What this trial is testingTriamcinolone Acetonide in Silicone-Filled Eyes as Adjunctive Treatment for Proliferative VitreoretinopathyWho this might be right forProliferative Vitreoretinopathy Shahid Beheshti University of Medical Sciences
Testing effectiveness (Phase 2)Study completedNCT02865031What this trial is testingDacorin for Proliferative VitreoretinopathyWho this might be right forPVR Cairo University 15
Large-scale testing (Phase 3)Study completedNCT02834559What this trial is testingProphylactic Intravitreal 5-Fluorouracil and Heparin to Prevent PVR in High-risk Patients With Retinal Detachment.Who this might be right forRhegmatogenous Retinal DetachmentHigh-risk for Proliferative Vitreoretinopathy (PVR) Universitätsklinikum Köln 326
Not applicableUnknownNCT05561569What this trial is testingAir Versus Gas Tamponade in Primary Retinal DetachmentWho this might be right forRetinal DetachmentProliferative Vitreoretinopathy Benha University 40
Testing effectiveness (Phase 2)Looking for participantsNCT05523869What this trial is testingIntravitreal Topotecan in the Repair of Rhegmatogenous Retinal Detachment with Proliferative VitreoretinopathyWho this might be right forProliferative Vitreoretinopathy in Rhegmatogenous Retinal Detachment Unity Health Toronto 50
Not applicableActive Not RecruitingNCT07787377What this trial is testingComparison of Visual Outcomes of Pars Plana Vitrectomy With and Without Injection Clexane for Rhegmatogenous Retinal Detachment Proliferative VitreoretinopathyWho this might be right forRhegmatogenous Retinal Detachment With Grade C Proliferative Vitreoretinopathy Lahore General Hospital 60
Not applicableNot Yet RecruitingNCT07386678What this trial is testingStudy of Imaging and Molecular Biomarkers in Uncomplicated Rhegmatogenous Retinal DetachmentWho this might be right forRetinal Detachment RhegmatogenousProliferative VitreoretinopathyProliferative Vitreoretinopathy in Rhegmatogenous Retinal Detachment University College, London 50
Testing effectiveness (Phase 2)Looking for participantsNCT06541574What this trial is testingPrevention of ProliFerative Vitreoretinopathy with Intravitreal MethotreXate in Primary Retinal DEtachment Repair (FIXER) TrialWho this might be right forProliferative VitreoretinopathyRhegmatogenous Retinal Detachment Cincinnati Eye Institute, Southwest Ohio 860
Early research (Phase 1)Not Yet RecruitingNCT06425419What this trial is testingThe Safety and Efficacy of Intravitreal Topotecan for the Treatment of Proliferative VitreoretinopathyWho this might be right forProliferative VitreoretinopathyProliferative Vitreo-RetinopathyRhegmatogenous Retinal Detachment Massachusetts Eye and Ear Infirmary 50
Not applicableStudy completedNCT04168255What this trial is testingDouble Retinal Tamponade for Retinal Detachment With PVR and Inferior Breaks.Who this might be right forRetinal Detachment Minia University 30