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Results for “WHO Grade 3 Glioma”

76 trials

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Showing 20 of 76 results

Early research (Phase 1)Ended earlyNCT01954030
What this trial is testing

Phase 1/2 CTO + Bevacizumab for Recurrent Glioma Post-Bevacizumab Failure

Who this might be right for
Malignant Glioma (WHO Grade III or IV)
Annick Desjardins 17
Not applicableStudy completedNCT00255671
What this trial is testing

Acute Side Effects in Patients Who Are Undergoing Stereotactic Radiosurgery for Brain Tumors or Other Brain Disorders

Who this might be right for
Brain and Central Nervous System TumorsMetastatic CancerRadiation Toxicity
Case Comprehensive Cancer Center 76
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07832123
What this trial is testing

Safusidenib for Patients With Newly Diagnosed IDH1-mutant CNS WHO Grade 3 Oligodendroglioma and Astrocytoma - a Single Arm Phase II Study

Who this might be right for
Glioma : Oligodendroglioma or Astrocytoma
University of Zurich 20
Testing effectiveness (Phase 2)Study completedNCT00070161
What this trial is testing

Phase II Studies Of Donepezil And Ginkgo Biloba In Irradiated Brain Tumor

Who this might be right for
Brain and Central Nervous System TumorsRadiation Toxicity
Wake Forest University Health Sciences 68
Early research (Phase 1)Looking for participantsNCT04573140
What this trial is testing

RNA-lipid Particle (RNA-LP) Vaccines for Newly Diagnosed Pediatric High-Grade Gliomas (pHGG) and Adult Glioblastoma (GBM)

Who this might be right for
Adult GlioblastomaHigh Grade GliomaWHO Grade III or IV Malignant Glioma
University of Florida 28
Large-scale testing (Phase 3)Looking for participantsNCT04166409
What this trial is testing

The Drugs Selumetinib vs. Carboplatin and Vincristine in Patients With Low-Grade Glioma

Who this might be right for
Low Grade AstrocytomaLow Grade GliomaMetastatic Low Grade Astrocytoma+3 more
National Cancer Institute (NCI) 170
Early research (Phase 1)Study completedNCT02454634
What this trial is testing

Phase I Trial of IDH1 Peptide Vaccine in IDH1R132H-mutated Grade III-IV Gliomas

Who this might be right for
Glioma
National Center for Tumor Diseases, Heidelberg 39
Early research (Phase 1)Ended earlyNCT00272870
What this trial is testing

Treatment of Newly Diagnosed Brain Tumors With Chemotherapy and Radiation Using Cells Modified for Chemoprotection and an Experimental Drug to Decrease the Tumor Cell Resistance to Chemotherapy

Who this might be right for
Glioblastoma Multiforme (WHO Grade IV)Anaplastic Astrocytoma (WHO Grade III)
Children's Hospital Medical Center, Cincinnati 1
Large-scale testing (Phase 3)Looking for participantsNCT06160492
What this trial is testing

Phase III Clinical Trial Evaluating the Resection Efficacy of 5-Aminolevulinic Acid Hydrochloride (5-ALA HCl) Fluorescence-Guided Microsurgery Versus Conventional White Light Microsurgery in Patients With Malignant Glioma (WHO Grade 3/4)

Who this might be right for
5-aminolevulinic AcidFluorescence-guided Resection
Lee's Pharmaceutical Limited 144
Early research (Phase 1)Active Not RecruitingNCT02208362
What this trial is testing

Genetically Modified T-cells in Treating Patients With Recurrent or Refractory Malignant Glioma

Who this might be right for
Recurrent GlioblastomaRecurrent Malignant GliomaRecurrent WHO Grade II Glioma+5 more
City of Hope Medical Center 65
Early research (Phase 1)Looking for participantsNCT04540107
What this trial is testing

Serial MR Imaging and MR Spectroscopic Imaging for the Characterization of Lower Grade Glioma

Who this might be right for
Recurrent World Health Organization (WHO) Grade II GliomaRecurrent WHO Grade III GliomaWHO Grade II Glioma+1 more
Susan Chang 300
Not applicableWithdrawnNCT03956706
What this trial is testing

Study of Stereotactic Radiosurgery to the Subventricular Zone in Malignant Gliomas

Who this might be right for
GlioblastomaAstrocytoma, Grade IIIAstrocytoma, Grade IV+1 more
Northwell Health
Testing effectiveness (Phase 2)Looking for participantsNCT05009992
What this trial is testing

Combination Therapy for the Treatment of Diffuse Midline Gliomas

Who this might be right for
Diffuse Intrinsic Pontine GliomaDiffuse Midline Glioma, H3 K27M-MutantRecurrent Diffuse Intrinsic Pontine Glioma+3 more
University of California, San Francisco 360
Early research (Phase 1)Looking for participantsNCT07755397
What this trial is testing

First in Human Multicenter Open Name Dose-increase, Consolidation Method to Study Safety Drug-level in Blood & Drug Metabolism Clinical Activity of Oral JBI-778 in Lung Cancer Patients With, Without Brain Metastasis IDH Mutated WHO Grade 3,4 Recurrent Glioma, Salivary Glands Tumor

Who this might be right for
NSCLC Patients With EGFR Activating MutationAdenoid Cystic Carcinoma MetastaticAdenoid Cystic Carcinoma of the Head and Neck
Jubilant Therapeutics India Limited 30
Testing effectiveness (Phase 2)Study completedNCT03779230
What this trial is testing

Safety and Efficacy of L19TNF in Patients With Isocitrate Dehydrogenase (IDH) Wildtype WHO Grade III / IV Glioma at First Relapse

Who this might be right for
Glioma of Brain
Philogen S.p.A. 20
Testing effectiveness (Phase 2)Active Not RecruitingNCT03919071
What this trial is testing

Dabrafenib Combined With Trametinib After Radiation Therapy in Treating Patients With Newly-Diagnosed High-Grade Glioma

Who this might be right for
Anaplastic AstrocytomaAnaplastic Astrocytoma, Not Otherwise SpecifiedAnaplastic Ganglioglioma+5 more
National Cancer Institute (NCI) 58
Testing effectiveness (Phase 2)Looking for participantsNCT06444412
What this trial is testing

An Investigational Scan (Ga-68 PSMA-11 PET/CT) for Detection of Disease Recurrence or Progression in Patients With Glioma

Who this might be right for
WHO Grade 3 GliomaWHO Grade 4 Glioma
Mayo Clinic 25
Not applicableActive Not RecruitingNCT03251027
What this trial is testing

Intensity-Modulated Stereotactic Radiation Therapy in Treating Patients With Grade II-IV Glioma

Who this might be right for
GlioblastomaWHO Grade II GliomaWHO Grade III Glioma
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University 100
Early research (Phase 1)Active Not RecruitingNCT03389230
What this trial is testing

Memory-Enriched T Cells in Treating Patients With Recurrent or Refractory Grade III-IV Glioma

Who this might be right for
GlioblastomaMalignant GliomaRecurrent Glioma+2 more
City of Hope Medical Center 29
Early research (Phase 1)Study completedNCT03434262
What this trial is testing

SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumors

Who this might be right for
Anaplastic AstrocytomaAnaplastic EpendymomaAnaplastic Ganglioglioma+53 more
St. Jude Children's Research Hospital 68
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