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Results for “WHO Grade 3 Glioma”

72 trials

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Showing 20 of 72 results

Very early researchEnded earlyNCT03927274
What this trial is testing

Intratumorally-Administered Topotecan Using Convection-Enhanced Delivery in Patients With Grade III/ IV Glioma

Who this might be right for
Glioma of Brain
H. Lee Moffitt Cancer Center and Research Institute 3
Early research (Phase 1)Study completedNCT02323880
What this trial is testing

Selinexor in Treating Younger Patients With Recurrent or Refractory Solid Tumors or High-Grade Gliomas

Who this might be right for
Malignant GliomaRecurrent Brain NeoplasmRecurrent Childhood Central Nervous System Neoplasm+7 more
Children's Oncology Group 59
Early research (Phase 1)Looking for participantsNCT04573140
What this trial is testing

RNA-lipid Particle (RNA-LP) Vaccines for Newly Diagnosed Pediatric High-Grade Gliomas (pHGG) and Adult Glioblastoma (GBM)

Who this might be right for
Adult GlioblastomaHigh Grade GliomaWHO Grade III or IV Malignant Glioma
University of Florida 28
Testing effectiveness (Phase 2)Study completedNCT02330562
What this trial is testing

Stage 1: Marizomib + Bevacizumab in WHO Gr IV GBM; Stage 2: Marizomib Alone; Stage 3: Combination of Marizomib and Bevacizumab

Who this might be right for
Malignant GliomaGlioblastoma
Celgene 121
Testing effectiveness (Phase 2)Looking for participantsNCT06161974
What this trial is testing

Study of Olutasidenib and Temozolomide in HGG

Who this might be right for
High Grade GliomaAstrocytomaAstrocytoma, Grade III+16 more
Rigel Pharmaceuticals 60
Testing effectiveness (Phase 2)Looking for participantsNCT06444412
What this trial is testing

An Investigational Scan (Ga-68 PSMA-11 PET/CT) for Detection of Disease Recurrence or Progression in Patients With Glioma

Who this might be right for
WHO Grade 3 GliomaWHO Grade 4 Glioma
Mayo Clinic 25
Not applicableStudy completedNCT00255671
What this trial is testing

Acute Side Effects in Patients Who Are Undergoing Stereotactic Radiosurgery for Brain Tumors or Other Brain Disorders

Who this might be right for
Brain and Central Nervous System TumorsMetastatic CancerRadiation Toxicity
Case Comprehensive Cancer Center 76
Not applicableLooking for participantsNCT04479696
What this trial is testing

Customized Neuro-Imaging Referenced Symptom Video for the Reduction of Patient and Caregiver Anxiety Around Radiation Treatment for Brain Tumors

Who this might be right for
GlioblastomaWHO Grade II GliomaWHO Grade III Glioma
M.D. Anderson Cancer Center 117
Large-scale testing (Phase 3)Looking for participantsNCT06160492
What this trial is testing

Phase III Clinical Trial Evaluating the Resection Efficacy of 5-Aminolevulinic Acid Hydrochloride (5-ALA HCl) Fluorescence-Guided Microsurgery Versus Conventional White Light Microsurgery in Patients With Malignant Glioma (WHO Grade 3/4)

Who this might be right for
5-aminolevulinic AcidFluorescence-guided Resection
Lee's Pharmaceutical Limited 144
Early research (Phase 1)Ended earlyNCT01989052
What this trial is testing

Ph 1/2 CTO With Lomustine for Bevacizumab-Naive Recurrent Glioma

Who this might be right for
Malignant Glioma (WHO Grade III or IV)
Annick Desjardins 9
Not applicableLooking for participantsNCT06975332
What this trial is testing

Local, Targeted Therapy With Alpha Emitter [225Ac]Ac-DOTA-SP (TAT) in Glioma (WHO G3-G4) Progression

Who this might be right for
GlioblastomaHigh-Grade GliomasGrade III Astrocytoma+1 more
Medical University of Warsaw 35
Testing effectiveness (Phase 2)Study completedNCT03779230
What this trial is testing

Safety and Efficacy of L19TNF in Patients With Isocitrate Dehydrogenase (IDH) Wildtype WHO Grade III / IV Glioma at First Relapse

Who this might be right for
Glioma of Brain
Philogen S.p.A. 20
Not applicableStudy completedNCT03323450
What this trial is testing

Cognitive Remediation Therapy for Brain Tumor Patients: Improving Working Memory

Who this might be right for
GliomaBrain Tumor, Primary
Virginia Commonwealth University 20
Very early researchStudy completedNCT02278510
What this trial is testing

Topotecan Using Convection-Enhanced Delivery (CED) in High Grade Glioma

Who this might be right for
Malignant GliomaWHO Grade III or IV Recurrent Glioma
Michael Vogelbaum, MD, PhD 3
Testing effectiveness (Phase 2)Looking for participantsNCT05765812
What this trial is testing

Debio 0123 in Combination With Temozolomide in Adult Participants With Recurrent or Progressive Glioblastoma and of Debio 0123 in Combination With Temozolomide and Radiotherapy in Adult Participants With Newly Diagnosed Glioblastoma

Who this might be right for
Glioblastoma IDH (Isocitrate Dehydrogenase) WildtypeAstrocytoma, Grade III
Debiopharm International SA 116
Large-scale testing (Phase 3)Looking for participantsNCT04166409
What this trial is testing

The Drugs Selumetinib vs. Carboplatin and Vincristine in Patients With Low-Grade Glioma

Who this might be right for
Low Grade AstrocytomaLow Grade GliomaMetastatic Low Grade Astrocytoma+3 more
National Cancer Institute (NCI) 170
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07206849
What this trial is testing

Study of Tovorafenib in High-Grade Glioma and Diffuse Intrinsic Pontine Glioma (DIPG)

Who this might be right for
High Grade Glioma (HGG) of the Brain With BRAF AberrationHigh Grade Glioma (III or IV)Diffuse Intrinsic Pontine Glioma+4 more
Nationwide Children's Hospital 79
Large-scale testing (Phase 3)Study completedNCT00369785
What this trial is testing

Donepezil in Treating Patients Who Have Undergone Radiation Therapy for Brain Tumors

Who this might be right for
Brain TumorsMetastatic Disease
Wake Forest University Health Sciences 198
Not applicableStudy completedNCT03450850
What this trial is testing

Study Of NOVOTTF-200A In Bevacizumab-Naive Subjects With Recurrent Grade III Malignant Astrocytoma

Who this might be right for
Astrocytoma, Grade III
Daniela A. Bota 1
Early research (Phase 1)Study completedNCT03434262
What this trial is testing

SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumors

Who this might be right for
Anaplastic AstrocytomaAnaplastic EpendymomaAnaplastic Ganglioglioma+53 more
St. Jude Children's Research Hospital 68
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