Not applicableStudy completedNCT00628745What this trial is testingTransthyretin Amyloidosis Outcome Survey (THAOS)Who this might be right forTransthyretin Gene MutationsTransthyretin Amyloidosis Pfizer 6,718
Large-scale testing (Phase 3)Enrolling By InvitationNCT06679946What this trial is testingEvaluate Vutrisiran in Patients With Transthyretin Amyloidosis With CardiomyopathyWho this might be right forTransthyretin Amyloidosis (ATTR) With Cardiomyopathy Alnylam Pharmaceuticals 700
Not applicableUnknownNCT05814380What this trial is testingThe Regional Scintigraphic DPD Uptake in Cardiac Transthyretin Amyloidosis.Who this might be right forTransthyretin Amyloidosis Katarzyna Holcman 100
Not applicableLooking for participantsNCT06291805What this trial is testingPhenotyping and Characterization of wtATTR-CM (TRACE 1)Who this might be right forTransthyretin AmyloidosisTransthyretin Amyloid CardiomyopathyWild-Type Transthyretin-Related (ATTR)Amyloidosis+1 more Steen Hvitfeldt Poulsen 120
Not applicableLooking for participantsNCT05697861What this trial is testingLong-Term Follow-Up (LTFU) of Subjects Dosed With NTLA-2001Who this might be right forTransthyretin-Related (ATTR) Familial Amyloid PolyneuropathyTransthyretin-Related (ATTR) Familial Amyloid CardiomyopathyWild-Type Transthyretin Cardiac Amyloidosis Intellia Therapeutics 72
Not applicableLooking for participantsNCT04561518What this trial is testingConTTRibute: A Global Observational Study of Patients With Transthyretin (TTR)-Mediated Amyloidosis (ATTR Amyloidosis)Who this might be right forTransthyretin-Mediated AmyloidosisATTR Amyloidosis Alnylam Pharmaceuticals 1,500
Not applicableLooking for participantsNCT07235462What this trial is testingLearn About the Use of Acoramidis in Patients With a Heart Condition Called Transthyretin Amyloid Cardiomyopathy (ATTR-CM) in a Real-world SettingWho this might be right forTransthyretin Amyloid Cardiomyopathy (ATTR-CM) Bayer 2,000
Not applicableStudy completedNCT04276220What this trial is testingPrevalence of wtATTR-CM After Carpal Tunnel Release SurgeryWho this might be right forTransthyretin AmyloidosisTransthyretin Cardiac AmyloidosisWild-Type Transthyretin-Related (ATTR)Amyloidosis Steen Hvitfeldt Poulsen 109
Not applicableStudy completedNCT06261216What this trial is testingAssociation Between Lifetime Physical Activity and Exercise and the Development of Wild-type Transthyretin Amyloid CardiomyopathyWho this might be right forAmyloid CardiomyopathyWild Type ATTR Amyloidosis Medical University of Graz 180
Very early researchActive Not RecruitingNCT05023889What this trial is testingSpectrum of Peripheral and Autonomic Neuropathies in Patients With aTTRwt Amyloidosis and Response to Patisiran TherapyWho this might be right forPolyneuropathiesWild Type ATTR AmyloidosisWild-Type Transthyretin-Related (ATTR)Amyloidosis+2 more Austin Neuromuscular Center 10
Not applicableUnknownNCT04563286What this trial is testingPatient-Reported Outcome Measures in Wild-Type and Variant Cardiac Transthyretin AmyloidosisWho this might be right forTransthyretin Amyloidosis University of Messina 250
Early research (Phase 1)Study completedNCT04601051What this trial is testingStudy to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of NTLA-2001 in Patients With Hereditary Transthyretin Amyloidosis With Polyneuropathy (ATTRv-PN) and Patients With Transthyretin Amyloidosis-Related Cardiomyopathy (ATTR-CM)Who this might be right forTransthyretin-Related (ATTR) Familial Amyloid PolyneuropathyTransthyretin-Related (ATTR) Familial Amyloid CardiomyopathyWild-Type Transthyretin Cardiac Amyloidosis Intellia Therapeutics 72
Large-scale testing (Phase 3)Looking for participantsNCT06128629What this trial is testingMAGNITUDE: A Phase 3 Study of NTLA-2001 in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR-CM)Who this might be right forTransthyretin Amyloidosis (ATTR) With Cardiomyopathy Intellia Therapeutics 1,200
Large-scale testing (Phase 3)Active Not RecruitingNCT04153149What this trial is testingHELIOS-B: A Study to Evaluate Vutrisiran in Patients With Transthyretin Amyloidosis With CardiomyopathyWho this might be right forTransthyretin Amyloidosis (ATTR) With Cardiomyopathy Alnylam Pharmaceuticals 655
Not applicableLooking for participantsNCT06465810What this trial is testingNon-interventional Study of Patients With Transthyretin (ATTR) AmyloidosisWho this might be right forTransthyretin AmyloidosisATTR-CMATTRv-PN+3 more AstraZeneca 1,850