Not applicableStudy completedNCT00628745What this trial is testingTransthyretin Amyloidosis Outcome Survey (THAOS)Who this might be right forTransthyretin Gene MutationsTransthyretin Amyloidosis Pfizer 6,718
Testing effectiveness (Phase 2)Study completedNCT03458130What this trial is testingStudy of AG10 in Amyloid CardiomyopathyWho this might be right forFamilial ATTR-CM (ATTRm-CM, or FAC)Wild-type ATTR-CM (ATTRwt-CM) Eidos Therapeutics, a BridgeBio company 49
Not applicableLooking for participantsNCT06034405What this trial is testingAnalysis of Lumbar Spine Stenosis Specimens for Identification of Transthyretin Cardiac AmyloidosisWho this might be right forLumbar Spinal StenosisCardiac AmyloidosisATTR Amyloidosis Wild Type+3 more Columbia University 1,663
Large-scale testing (Phase 3)Enrolling By InvitationNCT06679946What this trial is testingEvaluate Vutrisiran in Patients With Transthyretin Amyloidosis With CardiomyopathyWho this might be right forTransthyretin Amyloidosis (ATTR) With Cardiomyopathy Alnylam Pharmaceuticals 700
Not applicableUnknownNCT05814380What this trial is testingThe Regional Scintigraphic DPD Uptake in Cardiac Transthyretin Amyloidosis.Who this might be right forTransthyretin Amyloidosis Katarzyna Holcman 100
Large-scale testing (Phase 3)Study completedNCT00935012What this trial is testingSafety And Efficacy Evaluation Of Fx-1006a In Patients With V122i Or Wild-Type Transthyretin (TTR) Amyloid CardiomyopathyWho this might be right forATTR-CMTTR-CM Pfizer 31
Not applicableLooking for participantsNCT06291805What this trial is testingPhenotyping and Characterization of wtATTR-CM (TRACE 1)Who this might be right forTransthyretin AmyloidosisTransthyretin Amyloid CardiomyopathyWild-Type Transthyretin-Related (ATTR)Amyloidosis+1 more Steen Hvitfeldt Poulsen 120
Testing effectiveness (Phase 2)Study completedNCT00694161What this trial is testingThe Effects Of Fx-1006A On Transthyretin Stabilization And Clinical Outcome Measures In Patients With V122I Or Wild-Type TTR Amyloid CardiomyopathyWho this might be right forCardiomyopathy Pfizer 35
Not applicableUnknownNCT06186167What this trial is testingAmyloidosis Incidence in High-Risk Cardiac Device PatientsWho this might be right forAmyloidCardiac AmyloidosisAmyloidosis Cardiac+4 more Midwest Heart & Vascular Specialists 100
Not applicableNot Yet RecruitingNCT06499064What this trial is testingEOSS-ATTR Study (eHealth Based Operative Support System in ATTR-CM)Who this might be right forHeart FailureAmyloid CardiomyopathyATTR Amyloidosis Wild Type+1 more Hospital Universitari de Bellvitge 50
Not applicableUnknownNCT02260466What this trial is testingPrevalence and Post-surgical Outcomes of CARdiac Wild-type TransthyrEtin amyloidoSIs in Elderly Patients With Aortic steNosis Referred for Valvular Replacement.Who this might be right forHeart DiseaseAgingAmyloidosis+1 more French Cardiology Society 186
Not applicableStudy completedNCT01604122What this trial is testingBurden of Disease Study In Patients With Transthyretin Familial Amyloidosis Polyneuropathy (TTR-FAP) orTransthyretin Cardiomyopathy (TTR-CM) And CaregiversWho this might be right forTransthyretin Familial Amyloidosis Polyneuropathy (TTR-FAP)Transthyretin Cardiomyopathy (TTR-CM)Familial Amyloid Cardiomyopathy+1 more Pfizer 1
Not applicableEnrolling By InvitationNCT06412432What this trial is testingExercise Training and Rehabilitation In Cardiac AmyloidosisWho this might be right forCardiac Amyloidosis Federico II University 34
Not applicableLooking for participantsNCT07314268What this trial is testingATTR Amyloid Cardiomyopathy: Characterization of Extracellular Vesicles as Potential Disease Stratifiers and Prognostic BiomarkersWho this might be right forWild-type ATTR AmyloidosisAmyloidosis CardiacAmyloidosis, Hereditary+1 more University of Sao Paulo General Hospital 70
Not applicableLooking for participantsNCT05697861What this trial is testingLong-Term Follow-Up (LTFU) of Subjects Dosed With NTLA-2001Who this might be right forTransthyretin-Related (ATTR) Familial Amyloid PolyneuropathyTransthyretin-Related (ATTR) Familial Amyloid CardiomyopathyWild-Type Transthyretin Cardiac Amyloidosis Intellia Therapeutics 72
Testing effectiveness (Phase 2)Looking for participantsNCT06318260What this trial is testingHaemodynamic Effects of Dobutamine in Patients With Wild-type Transthyretin Amyloid Cardiomyopathy (ATTRwt)Who this might be right forATTR Amyloidosis Wild Type Steen Hvitfeldt Poulsen 35
Not applicableStudy completedNCT02792790What this trial is testingCarpal Tunnel Syndrome and Amyloid CardiomyopathyWho this might be right forAmyloidosisCardiomyopathyTransthyretin Amyloidosis+2 more The Cleveland Clinic 96
Testing effectiveness (Phase 2)Study completedNCT01677286What this trial is testingSafety and Effect of Doxycycline in Patients With AmyloidosisWho this might be right forAmyloidosis Boston University 25
Post-approval studies (Phase 4)Study completedNCT05633563What this trial is testingThe Effect of Trimetazidine on Mitochondrial Function, Myocardial Performance, and Invasive Hemodynamics in Patients Diagnosed With Wild-Type Transthyretin Cardiac AmyloidosisWho this might be right forTransthyretin Amyloid CardiopathyMitochondrial Pathology Steen Hvitfeldt Poulsen 24
Testing effectiveness (Phase 2)WithdrawnNCT02627820What this trial is testingThe Effect of an Antisense Oligonucleotide to Lower Transthyretin (TTR) Levels on the Progression of -Wild-type TTR Involving the HeartWho this might be right forAmyloidosis Brigham and Women's Hospital