Not applicableStudy completedNCT04312672What this trial is testingLong-term Follow-up Gene Therapy Study for RPGR- XLRPWho this might be right forX-Linked Retinitis Pigmentosa Janssen Research & Development, LLC 42
Testing effectiveness (Phase 2)UnknownNCT06492850What this trial is testingGene Therapy for RPGR Gene Mutation-associated X-linked Retinitis PigmentosaWho this might be right forX-Linked Retinitis Pigmentosa (XLRP) Frontera Therapeutics 32
Testing effectiveness (Phase 2)Enrolling By InvitationNCT06275620What this trial is testingA Study Comparing Two Doses of AGTC-501 in Male Participants With X-linked Retinitis Pigmentosa Caused by RPGR Mutations (DAWN)Who this might be right forX-Linked Retinitis Pigmentosa Beacon Therapeutics 24
Not applicableStudy completedNCT04868916What this trial is testingAn Observational Study of Japanese Participants With X-linked Retinitis PigmentosaWho this might be right forX-Linked Retinitis Pigmentosa Janssen Pharmaceutical K.K. 15
Large-scale testing (Phase 3)Active Not RecruitingNCT04850118What this trial is testingA Clinical Trial Evaluating the Safety and Efficacy of a Single Subretinal Injection of AGTC-501 in Participants With XLRPWho this might be right forX-Linked Retinitis Pigmentosa Beacon Therapeutics 85
Early research (Phase 1)Active Not RecruitingNCT06460844What this trial is testingStudy to Evaluate Safety of RTx-015 Injection in Retinitis Pigmentosa or Choroideremia Patients (ENVISION)Who this might be right forRetinitis PigmentosaChoroideremia Ray Therapeutics, Inc. 10
Not applicableLooking for participantsNCT01866371What this trial is testingHigh Resolution Retinal ImagingWho this might be right forStargardtsRetinitis PigmentosaAge-related Macular Degeneration+2 more University of Pennsylvania 600
Not applicableLooking for participantsNCT02435940What this trial is testingInherited Retinal Degenerative Disease RegistryWho this might be right forEye Diseases HereditaryRetinal DiseaseAchromatopsia+25 more Foundation Fighting Blindness 20,000
Not applicableStudy completedNCT04926129What this trial is testingNatural History of the Progression of X-Linked Retinitis PigmentosaWho this might be right forX-Linked Retinitis Pigmentosa NightstaRx Ltd, a Biogen Company 201
Not applicableEnded earlyNCT03561922What this trial is testingImpact on Daily Life of Patients Using the Subretinal Implant RETINA IMPLANT Alpha AMSWho this might be right forRetinal DegenerationInherited Retinal Dystrophy Primarily Involving Sensory Retina Retina Implant AG 2
Not applicableLooking for participantsNCT05554835What this trial is testingGlobal Registry and Natural History Study for Mitochondrial DisordersWho this might be right forMitochondrial DiseasesKearns-Sayre SyndromeMIDD+15 more LMU Klinikum 6,000
Testing effectiveness (Phase 2)Active Not RecruitingNCT04517149What this trial is testing4D-125 in Patients With X-Linked Retinitis Pigmentosa (XLRP)Who this might be right forX-Linked Retinitis Pigmentosa 4D Molecular Therapeutics 21
Large-scale testing (Phase 3)Active Not RecruitingNCT04794101What this trial is testingFollow-up Gene Therapy Trial for the Treatment of X-linked Retinitis Pigmentosa Associated With Variants in the RPGR GeneWho this might be right forX-Linked Retinitis Pigmentosa Janssen Research & Development, LLC 97
Testing effectiveness (Phase 2)Active Not RecruitingNCT06333249What this trial is testingA Study Comparing Two Doses of AGTC-501 in Male Subjects With X-linked Retinitis Pigmentosa Caused by RPGR Mutations (SKYLINE)Who this might be right forX-Linked Retinitis Pigmentosa Beacon Therapeutics 14
Large-scale testing (Phase 3)Active Not RecruitingNCT05926583What this trial is testingAAV5-hRKp.RPGR for the Treatment of Japanese Participants With X-linked Retinitis PigmentosaWho this might be right forRetinitis Pigmentosa Janssen Pharmaceutical K.K. 4
Testing effectiveness (Phase 2)Study completedNCT01461213What this trial is testingGene Therapy for Blindness Caused by ChoroideremiaWho this might be right forChoroideremia University of Oxford 14
Not applicableLooking for participantsNCT06092346What this trial is testingA Natural History Study Seeks to Understand the Clinical, Genomic, Pharmacological, Laboratory, and Dietary Determinates of Pyrimidine and Purine Metabolism DisordersWho this might be right forAMPD3, OMIM*102772, AMP Deaminase DeficiencyAK1, OMIM *103000, Adenylate Kinase DeficiencyAMPD1, OMIM *102770, Myopathy Due to Myoadenylate Deaminase Deficiency+25 more National Human Genome Research Institute (NHGRI)
Testing effectiveness (Phase 2)Study completedNCT05282953What this trial is testingA Phase I/II Dose-escalating Study of the Safety, Tolerability and Efficacy of KIO-301 Administered Intravitreally to Patients With Retinitis Pigmentosa and Choroideremia (ABACUS)Who this might be right forRetinitis PigmentosaChoroideremiaNon-Syndromic Rod-Dominant Inherited Retinal Diseases Kiora Pharmaceuticals, Inc. 32
Testing effectiveness (Phase 2)Active Not RecruitingNCT07174726What this trial is testingOpen-label Study to Evaluate the Safety of Laruparetigene Zovaparvovec Administered Bilaterally in Male Participants With X-Linked Retinitis PigmentosaWho this might be right forX-Linked Retinitis Pigmentosa (XLRP) Beacon Therapeutics 10
Not applicableStudy completedNCT03314207What this trial is testingClinical Evaluation of Patients With X-linked Retinitis Pigmentosa (XLRP)Who this might be right forX-Linked Retinitis Pigmentosa Beacon Therapeutics 14