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Results for “X-linked Severe Combined Immunodeficiency”

41 trials

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Showing 20 of 41 results

Large-scale testing (Phase 3)Study completedNCT00220766
What this trial is testing

Rapid Infusion of Immune Globulin Intravenous (Human) In Primary Immunodeficiency Patients

Who this might be right for
Immunologic Deficiency SyndromeAgammaglobulinemiaSevere Combined Immunodeficiency+2 more
Grifols Therapeutics LLC 100
Testing effectiveness (Phase 2)Enrolling By InvitationNCT01852370
What this trial is testing

Sequential Cadaveric Lung and Bone Marrow Transplant for Immune Deficiency Diseases

Who this might be right for
Severe Combined Immunodeficiency (SCID)Immunodeficiency With Predominant T-cell Defect, UnspecifiedSevere Chronic Neutropenia+6 more
Paul Szabolcs 16
Not applicableUnknownNCT01175239
What this trial is testing

Gene Therapy for X-linked Severe Combined Immunodeficiency (SCID-X1)

Who this might be right for
X-linked Severe Combined Immunodeficiency
Great Ormond Street Hospital for Children NHS Foundation Trust 1
Not applicableLooking for participantsNCT04528355
What this trial is testing

Data Collection Study of Patients With Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT With RIC

Who this might be right for
Primary Immunodeficiency (PID)Congenital Bone Marrow Failure SyndromesInherited Metabolic Disorders (IMD)+2 more
Paul Szabolcs 50
Testing effectiveness (Phase 2)Study completedNCT01129544
What this trial is testing

Gene Transfer for Severe Combined Immunodeficiency, X-linked (SCID-X1) Using a Self-inactivating (SIN) Gammaretroviral Vector

Who this might be right for
Severe Combined Immunodeficiency
David Williams 8
Not applicableLooking for participantsNCT00128973
What this trial is testing

Evaluation of Patients With Immune Function Abnormalities

Who this might be right for
Chronic Granulomatous Disease (CGD)X-Linked Severe Combined Immune Deficiency (XSCID)Leukocyte Adhesion Deficiency 1 (LAD)+1 more
National Institute of Allergy and Infectious Diseases (NIAID) 3,500
Testing effectiveness (Phase 2)Looking for participantsNCT03311503
What this trial is testing

Phase I/II Trial of Lentiviral Gene Transfer for SCID-X1 With Low Dose Targeted Busulfan Conditioning

Who this might be right for
Severe Combined Immunodeficiency, X LinkedGene Therapy
David Williams 12
Early research (Phase 1)Study completedNCT00028236
What this trial is testing

Stem Cell Gene Therapy to Treat X-Linked Severe Combined Immunodeficiency (XSCID)

Who this might be right for
Severe Combined Immunodeficiency
National Institute of Allergy and Infectious Diseases (NIAID) 3
Not applicableUnknownNCT01346150
What this trial is testing

Patients Treated for SCID (1968-Present)

Who this might be right for
SCIDADA-SCIDXSCID+3 more
National Institute of Allergy and Infectious Diseases (NIAID) 1,007
Not applicableEnrolling By InvitationNCT01186913
What this trial is testing

Natural History Study of SCID Disorders

Who this might be right for
Severe Combined Immunodeficiency (SCID)Leaky SCIDOmenn Syndrome+3 more
National Institute of Allergy and Infectious Diseases (NIAID) 690
Not applicableUnknownNCT00596999
What this trial is testing

A Single-arm Safety Study of Transplantation Using Umbilical Cord Blood and Human Placental-derived Stem Cells From Partially Matched Related Donors in Persons With Certain Malignant Blood Diseases and Non-malignant Disorders

Who this might be right for
Hematologic Malignancies
Celgene Corporation 6
Not applicableStudy completedNCT05687474
What this trial is testing

Baby Detect : Genomic Newborn Screening

Who this might be right for
Congenital Adrenal HyperplasiaFamilial Hyperinsulinemic Hypoglycemia 1Phosphoglucomutase 1 Deficiency+121 more
Centre Hospitalier Universitaire de Liege 6,824
Not applicableStudy completedNCT02600364
What this trial is testing

Diversion-p64 Post Market Clinical Follow-Up Study to Assess Safety and Effectiveness of the p64 Flow Modulation Device

Who this might be right for
Intracranial Aneurysm
Phenox GmbH 450
Not applicableUnknownNCT04286815
What this trial is testing

Gene Therapy for X Linked Severe Combined Immunodeficiency

Who this might be right for
Gene Therapy
Children's Hospital of Chongqing Medical University 10
Not applicableStudy completedNCT00006335
What this trial is testing

Influences on Female Adolescents' Decisions Regarding Testing for Carrier Status of XSCID

Who this might be right for
Severe Combined Immunodeficiency
National Human Genome Research Institute (NHGRI) 40
Not applicableEnrolling By InvitationNCT03655223
What this trial is testing

Early Check: Expanded Screening in Newborns

Who this might be right for
Spinal Muscular AtrophyFragile X SyndromeFragile X - Premutation+182 more
RTI International 30,000
Testing effectiveness (Phase 2)Study completedNCT01410019
What this trial is testing

Gene Therapy for X-linked Severe Combined Immunodeficiency

Who this might be right for
X-linked Severe Combined Immunodeficiency
Assistance Publique - Hôpitaux de Paris 5
Testing effectiveness (Phase 2)Looking for participantsNCT01962415
What this trial is testing

Reduced Intensity Conditioning for Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT

Who this might be right for
Primary Immunodeficiency (PID)Congenital Bone Marrow Failure SyndromesInherited Metabolic Disorders (IMD)+4 more
Paul Szabolcs 100
Early research (Phase 1)Ended earlyNCT02231710
What this trial is testing

Safety Study of Gene Modified Donor T Cell Infusion After Stem Cell Transplant for Non-Malignant Diseases

Who this might be right for
Primary Immune Deficiency DisordersHemophagocytic LymphohistiocytosisInherited Bone Marrow Failure Syndrome+2 more
Bellicum Pharmaceuticals 1
Not applicableAvailableNCT06731036
What this trial is testing

Expanded Access to CD34+ Selection Utilizing Miltenyi CliniMACS Prodigy® for Patients Receiving Peripheral Blood Stem Cell Transplantations and Stem Cell Boosts

Who this might be right for
Severe Combined ImmunodeficiencyFanconi AnemiaDyskeratosis Congenita+1 more
University of Florida
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