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Results for “XLA”

197 trials

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Showing 20 of 197 results

Early research (Phase 1)Ended earlyNCT02292225
What this trial is testing

Duvelisib With Obinutuzumab in Patients With CLL/SLL Previously Treated With a BTKi (SYNCHRONY)

Who this might be right for
Lymphocytic Leukemia, ChronicLymphoma, Small Lymphocytic
SecuraBio 3
Early research (Phase 1)Study completedNCT04564040
What this trial is testing

A Study in Healthy Subjects to Assess Bioavailability (Proportion of a Drug Which Enters the Circulation to Have an Active Effect) of Acalabrutinib Tablet and Protonpump Inhibitor Effect (Members of a Class of Medications That Inhibits in Gastric Acid Production) for Rabeprazole

Who this might be right for
Mantle Cell LymphomaCOVID-19
AstraZeneca 20
Testing effectiveness (Phase 2)Ended earlyNCT02272686
What this trial is testing

Ibrutinib Post Stem Cell Transplantation (SCT) in Double-Hit B-Cell Lymphoma

Who this might be right for
Lymphoma
M.D. Anderson Cancer Center 1
Testing effectiveness (Phase 2)Study completedNCT02169180
What this trial is testing

Study of the Bruton's Tyrosine Kinase (BTK) Inhibitor Ibrutinib in Participants With Relapsed or Refractory Mantle Cell Lymphoma

Who this might be right for
Lymphoma, Mantle-cell
Janssen Pharmaceutical K.K. 16
Testing effectiveness (Phase 2)Study completedNCT02195869
What this trial is testing

Study of the Bruton's Tyrosine Kinase Inhibitor in Subjects With Chronic Graft Versus Host Disease

Who this might be right for
Graft Versus Host Disease
Pharmacyclics LLC. 45
Early research (Phase 1)Looking for participantsNCT05131022
What this trial is testing

NX-5948 in Adults With Relapsed/Refractory B-cell Malignancies

Who this might be right for
Chronic Lymphocytic Leukemia (CLL)Small Lymphocytic Lymphoma (SLL)Diffuse Large B Cell Lymphoma (DLBCL)+6 more
Nurix Therapeutics, Inc. 572
Testing effectiveness (Phase 2)Study completedNCT03889639
What this trial is testing

Dose-finding Study for SAR442168 in Relapsing Multiple Sclerosis

Who this might be right for
Relapsing Multiple Sclerosis
Sanofi 130
Testing effectiveness (Phase 2)Study completedNCT01325701
What this trial is testing

Safety and Efficacy Study of a BTK Inhibitor in Subjects With Relapsed or Refractory Diffuse Large B-cell Lymphoma

Who this might be right for
Diffuse Large Cell B-lymphoma
Pharmacyclics LLC. 78
Early research (Phase 1)Study completedNCT02303392
What this trial is testing

Selinexor and Ibrutinib in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia or Aggressive Non-Hodgkin Lymphoma

Who this might be right for
Prolymphocytic LeukemiaRecurrent Adult Diffuse Large Cell LymphomaRecurrent Mantle Cell Lymphoma+2 more
Jennifer Woyach 34
Testing effectiveness (Phase 2)Study completedNCT02784106
What this trial is testing

Safety and Efficacy Study of M2951 in Participants With Rheumatoid Arthritis

Who this might be right for
Rheumatoid Arthritis
EMD Serono Research & Development Institute, Inc. 65
Testing effectiveness (Phase 2)Study completedNCT03206970
What this trial is testing

Study to Evaluate Efficacy and Safety of BGB-3111 in Participants With Relapsed or Refractory Mantle Cell Lymphoma (MCL)

Who this might be right for
Refractory Mantle Cell LymphomaRelapsed Mantle Cell Lymphoma
BeiGene 86
Not applicableStudy completedNCT04938141
What this trial is testing

MEOI and HRQoL in CLL Patients Treated With BTKis

Who this might be right for
Chronic Lymphocytic Leukemia
AstraZeneca 23
Testing effectiveness (Phase 2)Study completedNCT02077166
What this trial is testing

Ibrutinib in Combination With Lenalidomide and Rituximab in Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma

Who this might be right for
Relapsed Diffuse Large B-Cell LymphomaRefractory Diffuse Large B-Cell Lymphoma
Pharmacyclics LLC. 138
Testing effectiveness (Phase 2)Study completedNCT01980654
What this trial is testing

Study of Ibrutinib in Combination With Rituximab in Previously Untreated Subjects With Follicular Lymphoma

Who this might be right for
Follicular LymphomaB-cell LymphomaNon-Hodgkin's Lymphoma
Pharmacyclics LLC. 80
Testing effectiveness (Phase 2)Looking for participantsNCT07271667
What this trial is testing

Emavusertib + An Approved Bruton Tyrosine Kinase Inhibitor (BTKi) in Participants With Chronic Lymphocytic Leukemia (CLL) and Other B-cell Malignancies

Who this might be right for
Chronic Lymphocytic LeukemiaB-cell Malignancies
Curis, Inc. 108
Testing effectiveness (Phase 2)Study completedNCT02824029
What this trial is testing

Ibrutinib in Treating Patients With Relapsed or Refractory Classical Hodgkin Lymphoma

Who this might be right for
Classical Hodgkin LymphomaRecurrent Hodgkin LymphomaRefractory Hodgkin Lymphoma
Barbara Ann Karmanos Cancer Institute 28
Testing effectiveness (Phase 2)Study completedNCT03235544
What this trial is testing

INCB050465 in Relapsed or Refractory Mantle Cell Lymphoma Previously Treated With or Without a Bruton's Tyrosine Kinase (BTK) Inhibitor

Who this might be right for
Lymphoma
Incyte Corporation 162
Large-scale testing (Phase 3)Active Not RecruitingNCT06840392
What this trial is testing

Assess Efficacy Safety and Tolerability of Remibrutinib in Adult and Adolescent Patients With Moderate to Severe Hidradenitis Suppurativa

Who this might be right for
Hidradenitis Suppurativa
Novartis Pharmaceuticals 565
Testing effectiveness (Phase 2)Study completedNCT02362035
What this trial is testing

ACP-196 (Acalabrutinib) in Combination With Pembrolizumab, for Treatment of Hematologic Malignancies

Who this might be right for
Follicular Lymphoma (FL)CLLSmall Lymphocytic Lymphoma (SLL)+10 more
Acerta Pharma BV 161
Large-scale testing (Phase 3)Study completedNCT01963143
What this trial is testing

Bioequivalence Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Gammaplex® 10 and Gammaplex® 5% in Primary Immunodeficiency Diseases

Who this might be right for
Primary Immune Deficiency DisordersCommon Variable ImmunodeficiencyX-linked Agammaglobulinaemia+1 more
Bio Products Laboratory 48
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