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Results for “XLA”

202 trials

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Showing 20 of 202 results

Early research (Phase 1)Study completedNCT04564040
What this trial is testing

A Study in Healthy Subjects to Assess Bioavailability (Proportion of a Drug Which Enters the Circulation to Have an Active Effect) of Acalabrutinib Tablet and Protonpump Inhibitor Effect (Members of a Class of Medications That Inhibits in Gastric Acid Production) for Rabeprazole

Who this might be right for
Mantle Cell LymphomaCOVID-19
AstraZeneca 20
Early research (Phase 1)Looking for participantsNCT05780034
What this trial is testing

AC676 for the Treatment of Relapsed/Refractory B-Cell Malignancies

Who this might be right for
Relapsed/Refractory B-cell Malignancies
Accutar Biotechnology Inc 60
Testing effectiveness (Phase 2)Study completedNCT02824029
What this trial is testing

Ibrutinib in Treating Patients With Relapsed or Refractory Classical Hodgkin Lymphoma

Who this might be right for
Classical Hodgkin LymphomaRecurrent Hodgkin LymphomaRefractory Hodgkin Lymphoma
Barbara Ann Karmanos Cancer Institute 28
Large-scale testing (Phase 3)Looking for participantsNCT07277231
What this trial is testing

Investigate Sonrotoclax (BGB-11417) Plus Zanubrutinib (BGB-3111) Compared With Venetoclax Plus Acalabrutinib in Adults With Previously Untreated Chronic Lymphocytic Leukemia

Who this might be right for
Chronic Lymphocytic Leukemia
BeOne Medicines 500
Early research (Phase 1)Study completedNCT02556892
What this trial is testing

Bruton's Tyrosine Kinase (BTK) Inhibitor Ibrutinib in Participants With Treatment-naive Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

Who this might be right for
Lymphocytic Leukemia
Janssen Pharmaceutical K.K. 8
Testing effectiveness (Phase 2)Study completedNCT03088878
What this trial is testing

Cirmtuzumab and Ibrutinib in Patients With B-Cell Lymphoid Malignancies

Who this might be right for
B-cell Chronic Lymphocytic LeukemiaSmall Lymphocytic LymphomaMantle Cell Lymphoma+1 more
Oncternal Therapeutics, Inc 95
Testing effectiveness (Phase 2)Study completedNCT02077166
What this trial is testing

Ibrutinib in Combination With Lenalidomide and Rituximab in Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma

Who this might be right for
Relapsed Diffuse Large B-Cell LymphomaRefractory Diffuse Large B-Cell Lymphoma
Pharmacyclics LLC. 138
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07508995
What this trial is testing

Trial Of The Bruton Tyrosine Kinase Degrader BGB-16673 In Combination With BCL-2 Inhibitor Sonrotoclax For Patients With Treatment-Naive Chronic Lymphocytic Leukemia (CLL)

Who this might be right for
Chronic Lymphocytic Leukemia (CLL)
M.D. Anderson Cancer Center 40
Not applicableEnded earlyNCT00006054
What this trial is testing

Allogeneic Bone Marrow Transplantation in Patients With Primary Immunodeficiencies

Who this might be right for
Immunologic Deficiency SyndromesChediak-Higashi SyndromeCommon Variable Immunodeficiency+11 more
Fairview University Medical Center
Early research (Phase 1)UnknownNCT04173455
What this trial is testing

Study of the Safety, Tolerability and Pharmacokinetics of HZ-A-018 in Patients With B Cell Lymphoma

Who this might be right for
Lymphoma, B-Cell
First Affiliated Hospital of Zhejiang University 46
Large-scale testing (Phase 3)Study completedNCT02436668
What this trial is testing

Study of Ibrutinib vs Placebo, in Combination With Nab-paclitaxel and Gemcitabine, in the First Line Treatment of Patients With Metastatic Pancreatic Adenocarcinoma (RESOLVE)

Who this might be right for
Metastatic Pancreatic Adenocarcinoma
Pharmacyclics LLC. 430
Testing effectiveness (Phase 2)Study completedNCT05068440
What this trial is testing

Treatment of CD79B Mutant Relapsed/Refractory Diffuse Large B-Cell Lymphoma With Bruton Tyrosine Kinase Inhibitor Zanubrutinib

Who this might be right for
Relapsed Diffuse Large B-cell LymphomaRefractory Diffuse Large B-cell Lymphoma
BeiGene 65
Testing effectiveness (Phase 2)Study completedNCT03323151
What this trial is testing

Ixazomib and Ibrutinib in Relapsed/Refractory Mantle Cell Lymphoma

Who this might be right for
Mantle-Cell Lymphoma
PrECOG, LLC. 43
Not applicableUnknownNCT00004341
What this trial is testing

Study of Genetic and Molecular Defects in Primary Immunodeficiency Disorders

Who this might be right for
X-Linked AgammaglobulinemiaX-Linked Hyper IgM SyndromeWiskott-Aldrich Syndrome+1 more
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Testing effectiveness (Phase 2)Looking for participantsNCT06812715
What this trial is testing

Clonal Dynamics of Chronic Lymphocytic Leukaemia Treated With Pirtobrutinib After Previous Treatment With Zanubrutinib

Who this might be right for
Chronic Lymphocytic Leukemia
Peter MacCallum Cancer Centre, Australia 40
Testing effectiveness (Phase 2)Active Not RecruitingNCT02029443
What this trial is testing

ACP-196 (Acalabrutinib), a Novel Bruton Tyrosine Kinase (BTK) Inhibitor, for Treatment of Chronic Lymphocytic Leukemia, Richter's Syndrome or Prolymphocytic Leukemia

Who this might be right for
Chronic Lymphocytic LeukemiaSmall Lymphocytic LymphomaRichter's Syndrome+1 more
Acerta Pharma BV 306
Testing effectiveness (Phase 2)Looking for participantsNCT06333262
What this trial is testing

Fixed Duration Pirtobrutinib and Obinutuzumab in Chronic Lymphocytic Leukemia

Who this might be right for
Chronic Lymphocytic LeukemiaSmall Lymphocytic Lymphoma
Inhye Ahn 60
Testing effectiveness (Phase 2)Ended earlyNCT04305444
What this trial is testing

Study of a Triple Combination Therapy, DTRM-555, in Patients With R/R CLL or R/R Non-Hodgkin's Lymphomas

Who this might be right for
Relapsed Chronic Lymphocytic LeukemiaRefractory Chronic Lymphocytic LeukemiaDiffuse Large B Cell Lymphoma+2 more
Zhejiang DTRM Biopharma 55
Large-scale testing (Phase 3)Study completedNCT03053440
What this trial is testing

A Study Comparing BGB-3111 and Ibrutinib in Participants With Waldenström's Macroglobulinemia (WM)

Who this might be right for
Waldenström's Macroglobulinemia
BeiGene 201
Testing effectiveness (Phase 2)Ended earlyNCT04047797
What this trial is testing

Ixazomib and Rituximab in Treating Patients With Relapsed or Refractory Mantle Cell Lymphoma

Who this might be right for
Recurrent Mantle Cell LymphomaRefractory Mantle Cell Lymphoma
M.D. Anderson Cancer Center 3
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