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Results for “dMMR Cancer”

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Showing 20 of 0 results

Early research (Phase 1)Active Not RecruitingNCT05838768
What this trial is testing

Study of HRO761 Alone or in Combination in Cancer Patients With Specific DNA Alterations Called Microsatellite Instability or Mismatch Repair Deficiency.

Who this might be right for
MSIhi or dMMR Advanced Unresectable or Metastatic Solid Tumors, Including Colorectal Cancers
Novartis Pharmaceuticals 123
Testing effectiveness (Phase 2)WithdrawnNCT05419817
What this trial is testing

Pembrolizumab With Sitravatinib in Recurrent Endometrial Cancer and Other Solid Tumors With Deficient Mismatch Repair System

Who this might be right for
Recurrent Endometrial CancerSolid Tumors
Haider Mahdi
Testing effectiveness (Phase 2)Looking for participantsNCT06914297
What this trial is testing

TQB2450 Plus Progestin for Fertility-sparing Treatment in MMRd EC

Who this might be right for
Endometrial Cancer
Fudan University 10
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06426654
What this trial is testing

Sintilimab Combined With LDRT for Neoadjuvant Treatment of Locally Advanced dMMR/MSI-H Gastric Cancer

Who this might be right for
Gastric Cancer
West China Hospital 45
Large-scale testing (Phase 3)Active Not RecruitingNCT05173987
What this trial is testing

Study of Pembrolizumab (MK-3475) Versus Chemotherapy in Mismatch Repair Deficient (dMMR) Advanced or Recurrent Endometrial Carcinoma (MK-3475-C93/KEYNOTE-C93/GOG-3064/ENGOT-en15)

Who this might be right for
Endometrial Neoplasms
Merck Sharp & Dohme LLC 280
Very early researchEnded earlyNCT04906382
What this trial is testing

Tislelizumab for the Treatment of Recurrent Mismatch Repair Deficient Endometrial Cancer

Who this might be right for
Lynch SyndromeRecurrent Endometrial CarcinomaRecurrent Endometrial Clear Cell Adenocarcinoma+4 more
Floor Backes, MD 2
Testing effectiveness (Phase 2)UnknownNCT05913570
What this trial is testing

Cadonilimab as Neoadjuvant Therapy in Resectable Stage II-III MSI-H/dMMR Colorectal Cancer

Who this might be right for
Colorectal CancerMismatch Repair-deficient (dMMR)Microsatellite Instability-high (MSI-H)+1 more
LiuYing 22
Large-scale testing (Phase 3)Looking for participantsNCT05236972
What this trial is testing

PACE: PD-1 Antibody For dMMR/MSI-H Stage III Colorectal Cancer

Who this might be right for
Colorectal Carcinoma
Sun Yat-sen University 323
Testing effectiveness (Phase 2)Study completedNCT02060188
What this trial is testing

Nivolumab Alone or Nivolumab Combination Therapy in Colon Cancer That Has Come Back or Has Spread

Who this might be right for
Microsatellite Unstable Colorectal CancerMicrosatellite Stable Colorectal CancerMismatch Repair Proficient Colorectal Cancer+1 more
Bristol-Myers Squibb 385
Large-scale testing (Phase 3)Not Yet RecruitingNCT07740720
What this trial is testing

The Duration of Dostarlimab in Untreated Mismatch Repair Deficient (dMMR)/ Microsatellite Instability-high (MSI-H) Locally Advanced Rectal Cancer

Who this might be right for
Neoplasms, Rectal
GlaxoSmithKline 90
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06873854
What this trial is testing

LM-108 in Combination With Toripalimab in Subjects With Advanced Solid Tumours

Who this might be right for
Advanced Solid Tumor
LaNova Medicines Limited 84
Not applicableNot Yet RecruitingNCT07656740
What this trial is testing

Non-Operative Management and Following Immunotherapy for Colorectal Cancer and Other GI Cancers

Who this might be right for
Gastrointestinal CancerColorectal (Colon or Rectal) CancerStomach (Gastric) Cancer
Peking University Cancer Hospital & Institute 50
Not applicableStudy completedNCT04482608
What this trial is testing

The mCRC Patients With pMMR/MSS or dMMR/MSI-H Status Received Palliative Chemotherapy Efficacy and Survival

Who this might be right for
Colorectal Cancer MetastaticMismatch Repair DeficiencyMicrosatellite Instability High
Sun Yat-sen University 671
Testing effectiveness (Phase 2)UnknownNCT04636008
What this trial is testing

Sintilimab Plus Hypofractionated Radiotherapy for MSI-H/dMMR Rectal Cancer

Who this might be right for
Anti-PD-1 AntibodyRadiotherapyRectal Cancer+2 more
West China Hospital 20
Testing effectiveness (Phase 2)Looking for participantsNCT06278857
What this trial is testing

SATELLITE Study (feaSibility sAfeTy Efficacy dostarLimab earLy-stage defIcient endomeTrial cancEr)

Who this might be right for
Endometrial Cancer Stage IMmr DeficiencyEndometrioid Endometrial Adenocarcinoma+1 more
Queensland Centre for Gynaecological Cancer 10
Early research (Phase 1)Ended earlyNCT02952989
What this trial is testing

A Safety Study of SGN-2FF for Patients With Advanced Solid Tumors

Who this might be right for
Carcinoma, Non-Small-Cell LungCarcinoma, Renal CellBreast Neoplasms+5 more
Seagen Inc. 47
Not applicableLooking for participantsNCT07555210
What this trial is testing

Pilot Study of Bone Mineral Density Changes During Anti-PD-1 Immunotherapy

Who this might be right for
Breast Cancer (Triple Negative Breast Cancer (TNBC))Renal Cell Carcinoma (Kidney Cancer)Melanoma (Skin Cancer)+5 more
Jessica Mezzanotte Sharpe 25
Testing effectiveness (Phase 2)Not Yet RecruitingNCT05550558
What this trial is testing

Camrelizumab Plus Anlotinib in Patients With Recurrent Sporadic MMRd Endometrial Cancer

Who this might be right for
Endometrial Cancer
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University 43
Not applicableLooking for participantsNCT07269249
What this trial is testing

Real-world Efficacy and Safety of Neoadjuvant Dostarlimab in Patients With dMMR/MSI-H Locally Advanced Rectal Cancer

Who this might be right for
Locally Advanced Rectal Cancer (LARC)
National Cancer Institute, Naples 50
Large-scale testing (Phase 3)Active Not RecruitingNCT05652894
What this trial is testing

HX008 Compared to Chemotherapy in the First-Line Treatment of Subjects With MSI-H/dMMR Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
Taizhou Hanzhong biomedical co. LTD 190
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