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Results for “mTOR”

316 trials

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Showing 20 of 316 results

Not applicableStudy completedNCT04206124
What this trial is testing

MTORC1 and Autophagy in Human Brown Adipocytes

Who this might be right for
ObesityMetabolic Disease
University of New Mexico 24
Testing effectiveness (Phase 2)Looking for participantsNCT05104983
What this trial is testing

Stopping TSC Onset and Progression 2B: Sirolimus TSC Epilepsy Prevention Study

Who this might be right for
Tuberous Sclerosis ComplexEpilepsy
Darcy Krueger 64
Testing effectiveness (Phase 2)Study completedNCT01234857
What this trial is testing

Ridaforolimus (MK-8669) in Combination With Dalotuzumab (MK-0646) Compared to Standard of Care Treatment in Estrogen Receptor Positive Breast Cancer Patients (MK-8669-041 AM3)

Who this might be right for
Breast Cancer
Merck Sharp & Dohme LLC 115
Testing effectiveness (Phase 2)Study completedNCT00378703
What this trial is testing

Bevacizumab, Sorafenib Tosylate, and Temsirolimus in Treating Patients With Metastatic Kidney Cancer

Who this might be right for
Clear Cell Renal Cell CarcinomaRecurrent Renal Cell CarcinomaStage IV Renal Cell Cancer AJCC v7
National Cancer Institute (NCI) 361
Not applicableStudy completedNCT05054166
What this trial is testing

Efficacy of Everolimus-containing Chemotherapy in HER2- mBC Patients With PI3K/AKT/mTOR Mutations Study

Who this might be right for
Breast CancerPI3K/AKT/mTOR Pathway MutationEverolimus
Zhejiang Cancer Hospital 14
Not applicableStudy completedNCT03730428
What this trial is testing

Everolimus Related Pneumonitis in MBC

Who this might be right for
EverolimusPneumonitis
Fudan University 86
Post-approval studies (Phase 4)Study completedNCT02328963
What this trial is testing

Proportion of CMV Seropositive Kidney Transplant Recipients Who Will Develop a CMV Infection When Treated With an Immunosuppressive Regimen Including Everolimus and Reduced Dose of Cyclosporine Versus an Immunosuppressive Regimen With Mycophenolic Acid and Standard Dose of Cyclosporine A

Who this might be right for
Transplantation InfectionCytomegalovirus Infection
University Hospital, Bordeaux 186
Testing effectiveness (Phase 2)Study completedNCT02093598
What this trial is testing

POEM STUDY: A Phase IIa Trial in Endometrial Carcinoma With Temsirolimus

Who this might be right for
Carcinoma, EndometrioidmTOR Protein
MedSIR 10
Post-approval studies (Phase 4)Study completedNCT03525834
What this trial is testing

Safety and Efficacy of Everolimus (Afinitor®) in Chinese Adult Patients With Angiomyolipoma Associated With Tuberous Sclerosis Complex.

Who this might be right for
Renal Angiomyolipoma
Novartis Pharmaceuticals 40
Large-scale testing (Phase 3)Active Not RecruitingNCT04582136
What this trial is testing

Efficacy and Safety of Sirolimus in Active Systemic Lupus Erythematosus

Who this might be right for
Systemic Lupus Erythematosus
Chinese SLE Treatment And Research Group 146
Testing effectiveness (Phase 2)Looking for participantsNCT06463028
What this trial is testing

Sapanisertib and Serabelisib (PIKTOR) With Paclitaxel and a Substudy With an Insulin-Suppressing Diet in Patients With Advanced/Recurrent Endometrial Cancer

Who this might be right for
Endometrial Cancer
Faeth Therapeutics 40
Testing effectiveness (Phase 2)Study completedNCT02166944
What this trial is testing

Tamoxifen Treatment in Patients With Motor Neuron Disease

Who this might be right for
Amyotrophic Lateral SclerosisALS Functional Ration ScaleTAR-DNA-binding Protein-43+2 more
Taipei Medical University Shuang Ho Hospital 20
Early research (Phase 1)Study completedNCT01899053
What this trial is testing

A Safety and Pharmacokinetic Study of TAK-228 in Combination With TAK-117 in Adult Participants With Advanced Nonhematologic Malignancies

Who this might be right for
Advanced Nonhematologic Malignancies
Millennium Pharmaceuticals, Inc. 101
Testing effectiveness (Phase 2)Study completedNCT01797120
What this trial is testing

Study of Fulvestrant +/- Everolimus in Post-Menopausal, Hormone-Receptor + Metastatic Breast Ca Resistant to AI

Who this might be right for
Metastatic Breast Cancer
PrECOG, LLC. 131
Testing effectiveness (Phase 2)Ended earlyNCT02913131
What this trial is testing

Hyperpolarized C-13 Pyruvate as a Biomarker in Patients With Advanced Solid Tumor Malignancies

Who this might be right for
Prostate Cancer
Rahul Aggarwal 23
Post-approval studies (Phase 4)Study completedNCT01046045
What this trial is testing

Everolimus Rescue Immunosuppression in the Treatment of Chronic Allograft Dysfunction in Renal Transplant Recipients

Who this might be right for
Chronic Allograft Dysfunction in Renal Transplantation
Chinese University of Hong Kong 17
Large-scale testing (Phase 3)Study completedNCT01223027
What this trial is testing

Study of Dovitinib Versus Sorafenib in Patients With Metastatic Renal Cell Carcinoma

Who this might be right for
Metastatic Renal Cell Carcinoma
Novartis Pharmaceuticals 564
Early research (Phase 1)Temporarily pausedNCT01762410
What this trial is testing

Clinical Study of Oral PI3K/mTOR Inhibitor in Patients With Advanced Refractory Solid Tumors

Who this might be right for
Advanced Refractory Solid Tumors
Piramal Enterprises Limited 60
Not applicableStudy completedNCT00636090
What this trial is testing

Molecular, Genetic, and Genomic Assessments From Patients Treated With RAD001

Who this might be right for
Metastatic Hormone Refractory Prostate Cancer
Duke University 35
Testing effectiveness (Phase 2)Ended earlyNCT01420081
What this trial is testing

Two Dual PI3K/mTOR Inhibitors, PF-04691502 And PF-05212384 In Patients With Recurrent Endometrial Cancer

Who this might be right for
Endometrial Neoplasms
Pfizer 67
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