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Results for “mTOR”

325 trials

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Showing 20 of 325 results

Testing effectiveness (Phase 2)Study completedNCT03304678
What this trial is testing

Discovery of Sirolimus Sensitive Biomarkers in Blood

Who this might be right for
Lymphangioleiomyomatosis
National Heart, Lung, and Blood Institute (NHLBI) 33
Post-approval studies (Phase 4)UnknownNCT03781050
What this trial is testing

Efficacy of Rapamycin (Sirolimus) in the Treatment of Peutz-Jeghers Syndrome

Who this might be right for
Peutz-Jeghers Syndrome
Peking Union Medical College Hospital 10
Early research (Phase 1)Study completedNCT02587325
What this trial is testing

Phase 1/1b Study With Nab-sirolimus for Patients With Severe Pulmonary Arterial Hypertension

Who this might be right for
Pulmonary Hypertension
Aadi Bioscience, Inc. 15
Large-scale testing (Phase 3)Study completedNCT00790400
What this trial is testing

Efficacy and Safety of RAD001 in Patients Aged 18 and Over With Angiomyolipoma Associated With Either Tuberous Sclerosis Complex (TSC) or Sporadic Lymphangioleiomyomatosis (LAM)

Who this might be right for
Tuberous Sclerosis Complex (TSC)Lymphangioleiomyomatosis (LAM)
Novartis Pharmaceuticals 118
Early research (Phase 1)UnknownNCT01341834
What this trial is testing

Safety and Tolerability Study of RAD001 and LBH589 in All Solid Tumors With Enrichment for EBV Driven Tumors

Who this might be right for
Nasopharyngeal Carcinoma, Lymphomas, Any EBV+ Solid Tumour
National Cancer Centre, Singapore 49
Early research (Phase 1)Study completedNCT01364844
What this trial is testing

Safety and Tolerability of DS-7423 in Subjects With Advanced Solid Malignant Tumors

Who this might be right for
Solid TumorColorectal CancerEndometrial Cancer
Daiichi Sankyo 42
Testing effectiveness (Phase 2)Looking for participantsNCT05843253
What this trial is testing

Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant

Who this might be right for
High Grade GliomaDiffuse Intrinsic Pontine GliomaAnaplastic Astrocytoma+7 more
Nationwide Children's Hospital 120
Not applicableLooking for participantsNCT03955172
What this trial is testing

Efficiency of Everolimus for the Treatment of Kidney Transplanted Patients Presenting a Missing Self-induced NK-mediated Rejection

Who this might be right for
Kidney Transplant Failure and Rejection
Hospices Civils de Lyon 20
Early research (Phase 1)Study completedNCT00060645
What this trial is testing

Safety Study of AP23573 in Patients With Advanced, Refractory or Recurrent Malignancies (8669-013)(COMPLETED)

Who this might be right for
TumorsLymphomaMultiple Myeloma
Merck Sharp & Dohme LLC 33
Early research (Phase 1)Study completedNCT01470209
What this trial is testing

A Phase I Study of BKM120 and Everolimus in Advanced Solid Malignancies

Who this might be right for
Solid TumorsLung Cancer
Emory University 43
Large-scale testing (Phase 3)Not Yet RecruitingNCT07739914
What this trial is testing

Everolimus bAsed caLcineurin inhibiTor frEe immunosuppRession oNe Year AfTer lIver transplantatiON (ALTERNATION)

Who this might be right for
Liver AllograftLiver DiseasesLiver Transplantation
Hannover Medical School 150
Early research (Phase 1)Study completedNCT01204476
What this trial is testing

Cixutumumab, Everolimus, and Octreotide Acetate in Treating Patients With Advanced Low to Intermediate Grade Neuroendocrine Carcinoma

Who this might be right for
Gastrin-Producing Neuroendocrine TumorLung Carcinoid TumorMetastatic Digestive System Neuroendocrine Tumor G1+12 more
National Cancer Institute (NCI) 27
Testing effectiveness (Phase 2)Study completedNCT02874924
What this trial is testing

Effect of mTOR Inhibition and Other Metabolism Modulating Interventions on the Elderly

Who this might be right for
Aging
The University of Texas Health Science Center at San Antonio 34
Testing effectiveness (Phase 2)Study completedNCT01658436
What this trial is testing

BEZ235 Phase II Trial in Patients With Advanced Pancreatic Neuroendocrine Tumors (pNET) After Failure of mTOR Inhibitor Therapy.

Who this might be right for
Pancreatic Neuroendocrine Tumors (pNET)
Novartis Pharmaceuticals 31
Very early researchLooking for participantsNCT07065552
What this trial is testing

Tirzepatide in Obesity-Driven Endometrial Cancer

Who this might be right for
Endometrial CancerObesity
UNC Lineberger Comprehensive Cancer Center 20
Post-approval studies (Phase 4)UnknownNCT04993872
What this trial is testing

Pharmacokinetics of Calcineurin & mTOR Inhibitors in HIV-1 Infected Kidney Transplant Recipients After Switch to BIC/FTC/TAF

Who this might be right for
HIV-infected Patient Kidney Transplant Recipient
Institut de Médecine et d'Epidémiologie Appliquée - Fondation Internationale Léon M'Ba 5
Early research (Phase 1)Study completedNCT01523977
What this trial is testing

Everolimus With Multiagent Re-Induction Chemotherapy in Pediatric Patients With ALL

Who this might be right for
Acute Lymphoblastic Leukemia
Dana-Farber Cancer Institute 22
Early research (Phase 1)Study completedNCT06205381
What this trial is testing

Assessment of the Safety, Tolerability and Pharmacokinetics of AV078 in Healthy Volunteers

Who this might be right for
Healthy Participants
Aeovian Pharmaceuticals, Inc. 89
Not applicableUnknownNCT04112537
What this trial is testing

Dermatologic Patterns of Tuberous Sclerosis Patients and Somatic Mutation Relationship

Who this might be right for
Tuberous Sclerosis Complex
University Hospital, Montpellier 90
Testing effectiveness (Phase 2)Study completedNCT01265030
What this trial is testing

A Pilot Study Evaluating the Use of mTor Inhibitor Sirolimus in Children and Young Adults With Desmoid-Type Fibromatosis

Who this might be right for
Desmoid Tumor
MaineHealth 9
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