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Results for “mTOR”

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Active, Not Recruiting
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Enrolling by Invitation

Showing 20 of 0 results

Early research (Phase 1)Study completedNCT00907205
What this trial is testing

A Dose Escalation Study of SF1126, a PI3 Kinase (PI3K) Inhibitor, Given By Intravenous (IV) Infusion in Patients With Solid Tumors

Who this might be right for
Advanced or Metastatic Solid TumorsCancerSolid Cancers
Semafore Pharmaceuticals 44
Not applicableStudy completedNCT05198427
What this trial is testing

MTOR Inhibitors: the Lesions Induced by Papillomavirus for Transplant Patients.

Who this might be right for
Transplantation Organ
Hospices Civils de Lyon 45
Not applicableLooking for participantsNCT07774676
What this trial is testing

Effects of Obesity on Autophagy and mTORC1 Signalling in Skeletal Muscle

Who this might be right for
Overweight and Obese Adults
University of Birmingham 24
Not applicableStudy completedNCT03730428
What this trial is testing

Everolimus Related Pneumonitis in MBC

Who this might be right for
EverolimusPneumonitis
Fudan University 86
Testing effectiveness (Phase 2)Study completedNCT02093598
What this trial is testing

POEM STUDY: A Phase IIa Trial in Endometrial Carcinoma With Temsirolimus

Who this might be right for
Carcinoma, EndometrioidmTOR Protein
MedSIR 10
Testing effectiveness (Phase 2)Study completedNCT02332902
What this trial is testing

Everolimus for Treatment of Disfiguring Cutaneous Lesions in Neurofibromatosis1 CRAD001CUS232T

Who this might be right for
Neurofibromatosis 1
The University of Texas Health Science Center, Houston 24
Testing effectiveness (Phase 2)Looking for participantsNCT07037238
What this trial is testing

An Open-Label, Single-Arm Exploratory Clinical Study of Everolimus for the Treatment of Vascular Malformations

Who this might be right for
Vascular Malformations
Xuanwu Hospital, Beijing 10
Testing effectiveness (Phase 2)Study completedNCT01026623
What this trial is testing

Cixutumumab and Temsirolimus in Treating Patients With Metastatic Prostate Cancer

Who this might be right for
Hormone-Resistant Prostate CancerProstate AdenocarcinomaRecurrent Prostate Carcinoma+1 more
National Cancer Institute (NCI) 16
Testing effectiveness (Phase 2)Study completedNCT01077986
What this trial is testing

Everolimus, Cetuximab and Capecitabine in Patients With Metastatic Pancreatic Cancer

Who this might be right for
Metastatic Pancreatic Cancer
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 35
Testing effectiveness (Phase 2)Ended earlyNCT00923273
What this trial is testing

Sirolimus and Pemetrexed to Treat Non-Small Cell Lung Cancer

Who this might be right for
Carcinoma, Non-Small-Cell Lung
National Cancer Institute (NCI) 42
Testing effectiveness (Phase 2)Active Not RecruitingNCT04742777
What this trial is testing

Effect of mTOR Inhibition & Other Metabolism Modulating Interventions on the Elderly [SubStudy Rapa & cMRI to Evaluate Cardiac Function]

Who this might be right for
Aging
The University of Texas Health Science Center at San Antonio 20
Early research (Phase 1)Study completedNCT01920061
What this trial is testing

PF-05212384 In Combination With Other Anti-Tumor Agents and in Combination With Cisplatin in Patients With Triple Negative Breast Cancer in an Expansion Arm (TNBC)

Who this might be right for
Neoplasm
Pfizer 110
Early research (Phase 1)Ended earlyNCT02476955
What this trial is testing

Open-label Phase 1b Study of ARQ 092 in Combination With Anastrozole

Who this might be right for
Solid TumorsOvarian CancerEndometrial Cancer
ArQule, Inc., a subsidiary of Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc. (Rahway, NJ USA) 41
Testing effectiveness (Phase 2)Ended earlyNCT03740100
What this trial is testing

Single-arm Study With Bimiralisib in Patients With HNSCC Harboring NOTCH1 Loss of Function Mutations

Who this might be right for
HNSCC
M.D. Anderson Cancer Center 8
Testing effectiveness (Phase 2)Study completedNCT01234857
What this trial is testing

Ridaforolimus (MK-8669) in Combination With Dalotuzumab (MK-0646) Compared to Standard of Care Treatment in Estrogen Receptor Positive Breast Cancer Patients (MK-8669-041 AM3)

Who this might be right for
Breast Cancer
Merck Sharp & Dohme LLC 115
Not applicableApproved For MarketingNCT03817515
What this trial is testing

Expanded Access for ABI-009 in Patients With Advanced PEComa and Patients With a Malignancy With Relevant Genetic Mutations or mTOR Pathway Activation

Who this might be right for
PEComa, MalignantTSC1TSC2+1 more
Aadi Bioscience, Inc.
Not applicableEnded earlyNCT02306135
What this trial is testing

Identifying Mechanisms of Resistance to mTOR Inhibitors in Cancer

Who this might be right for
Cancer
Dartmouth-Hitchcock Medical Center 2
Very early researchNot Yet RecruitingNCT07813533
What this trial is testing

A Pilot Study to Examine the Efficacy and Tolerability of Sirolimus on Epidermal Nevi Lesions in Patients 6 Years Old and Above.

Who this might be right for
Epidermal Nevi
Northwestern University 14
Early research (Phase 1)Study completedNCT00655655
What this trial is testing

Everolimus and Vatalanib in Treating Patients With Advanced Solid Tumors

Who this might be right for
GastrinomaGlucagonomaInsulinoma+17 more
Mayo Clinic 96
Testing effectiveness (Phase 2)Study completedNCT01374750
What this trial is testing

Efficacy of Sirolimus In Liver Transplantation for Hepatocellular Carcinoma (HCC)

Who this might be right for
Hepatocellular Carcinoma
Seoul National University Hospital 45
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