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Results for “neurofibromatosis1 (NF1)”

174 trials

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Showing 20 of 174 results

Testing effectiveness (Phase 2)Study completedNCT01412892
What this trial is testing

Use of RAD001 as Monotherapy in the Treatment of Neurofibromatosis 1 Related Internal Plexiform Neurofibromas

Who this might be right for
Neurofibromatosis Type 1Plexiform NeurofibromaNeurofibromatoses
Assistance Publique - Hôpitaux de Paris 30
Testing effectiveness (Phase 2)Study completedNCT02839720
What this trial is testing

Selumetinib in Treating Patients With Neurofibromatosis Type 1 and Cutaneous Neurofibroma

Who this might be right for
Cutaneous NeurofibromaNeurofibromatosis Type 1Optic Nerve Glioma
National Cancer Institute (NCI) 11
Not applicableLooking for participantsNCT06360406
What this trial is testing

Real-World Treatment Study of Koselugo (Selumetinib)

Who this might be right for
Neurofibromatosis 1Neurofibroma, Plexiform
AstraZeneca 200
Not applicableUnknownNCT02680431
What this trial is testing

Analysis of Plasma for Diagnosis and Follow-up of Neurofibromatosis Type 1

Who this might be right for
Neurofibromatosis 1
Juha Peltonen 100
Not applicableUnknownNCT01777451
What this trial is testing

Whole Body Magnetic Resonance Imaging With Diffusion Weighted Imaging : Potential Role in Neurofibromatosis

Who this might be right for
Whole Body ImagingMagnetic Resonance ImagingNeurofibromatosis 1+2 more
Universitaire Ziekenhuizen KU Leuven 30
Not applicableUnknownNCT01218139
What this trial is testing

Analysis of Peripheral Nerve Sheath Tumors (PNSTs) in Neurofibromatosis Type 1 (NF1) Patients

Who this might be right for
Neurofibromatosis Type 1
KU Leuven 50
Testing effectiveness (Phase 2)Study completedNCT05005845
What this trial is testing

NFX-179 Topical Gel Treatment for Adults With Neurofibromatosis 1 (NF1) and Cutaneous Neurofibromas (cNF)

Who this might be right for
Cutaneous NeurofibromaNeurofibromatosis 1
NFlection Therapeutics, Inc. 199
Not applicableLooking for participantsNCT02544022
What this trial is testing

Development and Validation of Patient Reported Outcome (PRO) Measures for Individuals With Neurofibromatosis 1 (NF1) and Plexiform Neurofibromas (pNFs)

Who this might be right for
Neurofibromatosis 1Plexiform Neurofibromas
National Cancer Institute (NCI) 476
Not applicableStudy completedNCT01707836
What this trial is testing

Neurofibromatosis Type 1 Brain Tumor Genetic Risk

Who this might be right for
Neurofibromatosis Type 1Pediatric Brain Tumor
Washington University School of Medicine 176
Testing effectiveness (Phase 2)Study completedNCT03090971
What this trial is testing

Use of Topical Liquid Diclofenac Following Laser Microporation of Cutaneous Neurofibromas in Patients With NF1

Who this might be right for
Neurofibromatosis 1Cutaneous Neurofibroma
Fundação Educacional Serra dos Órgãos 7
Testing effectiveness (Phase 2)Study completedNCT03433183
What this trial is testing

SARC031: MEK Inhibitor Selumetinib (AZD6244) in Combination With the mTOR Inhibitor Sirolimus for Patients With Malignant Peripheral Nerve Sheath Tumors

Who this might be right for
Malignant Peripheral Nerve Sheath TumorsNeurofibromatosis 1
Sarcoma Alliance for Research through Collaboration 21
Not applicableStudy completedNCT04991428
What this trial is testing

Mechanism of Action of Transcranial Direct Current Stimulation in Neurofibromatosis Type 1

Who this might be right for
Neurofibromatosis 1
University of Manchester 31
Early research (Phase 1)Looking for participantsNCT06961565
What this trial is testing

PAS-004 in Adults Who Have Neurofibromatosis Type 1 With Plexiform Neurofibromas

Who this might be right for
NF1 MutationNeurofibroma PlexiformNeurofibroma, Plexiform+2 more
Pasithea Therapeutics Corp. 56
Early research (Phase 1)Study completedNCT00352599
What this trial is testing

Trial to Evaluate the Safety of Lovastatin in Individuals With Neurofibromatosis Type I (NF1)

Who this might be right for
Neurofibromatosis 1
University of California, Los Angeles 44
Not applicableLooking for participantsNCT05361811
What this trial is testing

Acceptance and Commitment Therapy for Caregivers of Children With a RASopathy: An Internal Pilot Feasibility Study and Follow-up Randomized Controlled Trial

Who this might be right for
Neurofibromatosis 1Noonan SyndromeLegius Syndrome+2 more
National Cancer Institute (NCI) 70
Testing effectiveness (Phase 2)Study completedNCT00754780
What this trial is testing

Clinical Trial of Pirfenidone in Adult Patients With Neurofibromatosis 1

Who this might be right for
Neurofibromatosis
Mayo Clinic 24
Not applicableStudy completedNCT05377008
What this trial is testing

Intervention Effectiveness on the Neurocognitive Functioning of Children and Adolescents With Neurofibromatosis Type 1

Who this might be right for
Neurocognitive DeficitMental Health ImpairmentNeurofibromatosis 1
Virginia Commonwealth University 38
Testing effectiveness (Phase 2)Ended earlyNCT03504501
What this trial is testing

Synaptic Plasticity and Cognitive Function in RASopathies

Who this might be right for
Impaired Synaptic PlasticityImpaired Cognition
Technical University of Munich 16
Early research (Phase 1)Study completedNCT06132165
What this trial is testing

Efficacy of Skin Cooling in Reducing Pain Associated With Non-invasive Treatments of Neurofibromatosis Type 1 Cutaneous Neurofibromas

Who this might be right for
Neurofibromatosis 1
Massachusetts General Hospital 13
Not applicableStudy completedNCT02777775
What this trial is testing

Targeting the Mechanisms Underlying Cutaneous Neurofibroma Formation in NF1: A Clinical Translational Approach.

Who this might be right for
Cutaneous NeurofibromasNeurofibromatosis Type 1Plexiform Neurofibromas
Corewell Health West 71
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