Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “neurofibromatosis1 (NF1)”

176 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 176 results

Not applicableUnknownNCT01777451
What this trial is testing

Whole Body Magnetic Resonance Imaging With Diffusion Weighted Imaging : Potential Role in Neurofibromatosis

Who this might be right for
Whole Body ImagingMagnetic Resonance ImagingNeurofibromatosis 1+2 more
Universitaire Ziekenhuizen KU Leuven 30
Early research (Phase 1)Ended earlyNCT04800822
What this trial is testing

PF-07284892 in Participants With Advanced Solid Tumors

Who this might be right for
Solid Tumor
Pfizer 53
Testing effectiveness (Phase 2)Study completedNCT00846430
What this trial is testing

Medical Treatment of "High-Risk" Neurofibromas

Who this might be right for
Neurofibromatosis 1
Corewell Health West 9
Not applicableStudy completedNCT01595139
What this trial is testing

MicroRNAs in Patients With Neurofibromatosis Type 1

Who this might be right for
GliomaNeurofibromatosis Type 1
Ann & Robert H Lurie Children's Hospital of Chicago 9
Testing effectiveness (Phase 2)Looking for participantsNCT04750928
What this trial is testing

Cyclin-Dependent Kinase (CDK)4/6 Inhibitor Abemaciclib for Neurofibromatosis Type I (NF1) Related Atypical Neurofibromas

Who this might be right for
Neurofibromatosis 1
National Cancer Institute (NCI) 55
Testing effectiveness (Phase 2)Active Not RecruitingNCT02407405
What this trial is testing

MEK 1/2 Inhibitor Selumetinib (AZD6244 Hydrogen Sulfate) in Adults With Neurofibromatosis Type 1 (NF1) and Inoperable Plexiform Neurofibromas

Who this might be right for
Neurofibromatosis 1 (NF1)Plexiform Neurofibromas (PN)
National Cancer Institute (NCI) 36
Not applicableLooking for participantsNCT05361811
What this trial is testing

Acceptance and Commitment Therapy for Caregivers of Children With a RASopathy: An Internal Pilot Feasibility Study and Follow-up Randomized Controlled Trial

Who this might be right for
Neurofibromatosis 1Noonan SyndromeLegius Syndrome+2 more
National Cancer Institute (NCI) 70
Testing effectiveness (Phase 2)Study completedNCT00030264
What this trial is testing

Combination Chemotherapy in Treating Patients With Neurofibromatosis and Progressive Plexiform Neurofibromas

Who this might be right for
Neurofibromatosis Type 1Precancerous Condition
Children's Hospital of Philadelphia 23
Testing effectiveness (Phase 2)Looking for participantsNCT06541847
What this trial is testing

A Phase 2, Open-Label Study to Evaluate the Safety and Effects of HLX-1502 in Patients With Neurofibromatosis Type 1

Who this might be right for
Neurofibromatosis Type 1
Healx Limited 25
Early research (Phase 1)Study completedNCT03649165
What this trial is testing

Evaluate Bioavailability and Food Effect of Selumetinib (AZD6244) in Healthy Male Participants

Who this might be right for
Neurofibromatosis Type 1 (NF1)-Related Plexiform Neurofibromas (PNs)Healthy Participants
AstraZeneca 24
Testing effectiveness (Phase 2)Ended earlyNCT03504501
What this trial is testing

Synaptic Plasticity and Cognitive Function in RASopathies

Who this might be right for
Impaired Synaptic PlasticityImpaired Cognition
Technical University of Munich 16
Testing effectiveness (Phase 2)Study completedNCT03326388
What this trial is testing

Intermittent Dosing Of Selumetinib In Childhood NF1 Associated Tumours

Who this might be right for
Neurofibromatosis Type 1Plexiform NeurofibromaOptic Nerve Glioma
Great Ormond Street Hospital for Children NHS Foundation Trust 14
Testing effectiveness (Phase 2)Study completedNCT04481035
What this trial is testing

Antioxidant Therapy With N-acetylcysteine for Learning and Motor Behavior in Children With Neurofibromatosis Type 1

Who this might be right for
Neurofibromatosis 1
Children's Hospital Medical Center, Cincinnati 5
Not applicableStudy completedNCT00684398
What this trial is testing

Adaptation and Quality of Life Among Adults With Neurofibromatosis Type I

Who this might be right for
Neurofibromatosis Type 1Von Recklinghausen DiseaseNF1
National Human Genome Research Institute (NHGRI) 645
Not applicableStudy completedNCT05912400
What this trial is testing

Evaluating Mitochondrial Dysfunction in Patients With Neurofibromatosis Type 1

Who this might be right for
Neurofibromatosis 1
University of Arkansas 55
Not applicableUnknownNCT06379230
What this trial is testing

A Retrospective Study on Epidemiological Characteristics of Chinese NF1 Patients in Real World (PROMISE)

Who this might be right for
Neurofibromatosis 1Plexiform Neurofibroma
Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University 2,000
Not applicableActive Not RecruitingNCT00924196
What this trial is testing

Natural History Study of Patients With Neurofibromatosis Type I

Who this might be right for
Neurofibromatosis Type 1Malignant Peripheral Nerve Sheath TumorPlexiform Neurofibroma+2 more
National Cancer Institute (NCI) 259
Testing effectiveness (Phase 2)UnknownNCT03741101
What this trial is testing

Treatment of NF1-related Plexiform Neurofibroma With Trametinib

Who this might be right for
Neurofibromatosis 1ChildNeurofibroma, Plexiform
Region Skane 15
Testing effectiveness (Phase 2)Active Not RecruitingNCT04954001
What this trial is testing

Study to Evaluate the Safety, Tolerability, PK Characteristics and Anti-tumor Activity of FCN-159 in Adult and Pediatric Participants With Neurofibromatosis Type 1

Who this might be right for
Neurofibromatosis 1Plexiform NeurofibromaNF1
Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd. 160
Testing effectiveness (Phase 2)Looking for participantsNCT06188741
What this trial is testing

Selumetinib for the Prevention of Plexiform Neurofibroma Growth in NF Type 1

Who this might be right for
Neurofibromatosis 1Plexiform Neurofibroma
University of Alabama at Birmingham 200
Load More Results