Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “pMMR”

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 0 results

Testing effectiveness (Phase 2)Looking for participantsNCT07005570
What this trial is testing

Short-course Radiotherapy Followed by Sequential Chemotherapy With or Without PD-1 Monoclonal Antibody and Bevacizumab as Total Neoadjuvant Therapy in pMMR/MSS Locally Advanced Rectal Cancer (SPARK)

Who this might be right for
pMMR/MSS Locally Advanced Rectal Cancer
Dechang Diao 86
Testing effectiveness (Phase 2)Looking for participantsNCT05965531
What this trial is testing

Treating Locally Advanced Rectal Cancer With TAS-102 Chemotherapy Plus Neoadjuvant Radiotherapy

Who this might be right for
Rectal Cancer
Sun Yat-sen University 65
Testing effectiveness (Phase 2)WithdrawnNCT05690035
What this trial is testing

Tislelizumab Combined With Fruquintinib for Metastatic pMMR/MSS Colorectal Cancer

Who this might be right for
Metastatic Colorectal CancermCRC
Sun Yat-sen University
Testing effectiveness (Phase 2)UnknownNCT04483219
What this trial is testing

Tyrosine Kinase Inhibitor (TKI) + Anti-PD-1 Antibody in TKI-responded Microsatellite Stability/Proficient Mismatch Repair (MSS/pMMR) Metastatic Colorectal Adenocarcinoma.

Who this might be right for
MSSpMMRMetastatic Colorectal Adenocarcinoma
China Medical University, China 53
Not applicableLooking for participantsNCT06890273
What this trial is testing

NIS to Examine the Effectiveness and Safety of Durvalumab and Olaparib in Patients With Endometrial Cancer (DUOLife)

Who this might be right for
Endometrial Cancer
AstraZeneca 150
Testing effectiveness (Phase 2)Looking for participantsNCT06764680
What this trial is testing

Oral Chemotherapy, Targeted Therapy and Immunotherapy With/Without Radiotherapy as 3rd- or Later-line Therapy for Advanced MSS/pMMR Colorectal Cancer

Who this might be right for
Colorectal Cancer MetastaticChemotherapyTargeted Therapy+2 more
Sun Yat-sen University 57
Testing effectiveness (Phase 2)UnknownNCT04527068
What this trial is testing

QL1101 in Combination With JS001 in Patients With pMMR/MSS Refractory Metastatic Colorectal Cancer

Who this might be right for
Refractory Metastatic Colorectal CancerpMMRMSS
Second Affiliated Hospital, Zhejiang University, School of Medicine 50
Large-scale testing (Phase 3)Not Yet RecruitingNCT07578649
What this trial is testing

Symbiotic-GYN-18: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Advanced or Recurrent MMR-proficient Endometrial Cancer

Who this might be right for
Endometrial NeoplasmsEndometrial Cancer
Pfizer 600
Not applicableNot Yet RecruitingNCT06823323
What this trial is testing

The Study on the Efficacy and Safety of Lactobacillus Johnsonii in Combination with CapeOX and Pembrolizumab for the Treatment of MSS/pMMR Metastatic Colorectal Cancer.

Who this might be right for
Metastatic Colorectal Cancer (CRC)
Second Affiliated Hospital, Zhejiang University, School of Medicine 150
Testing effectiveness (Phase 2)Looking for participantsNCT07544784
What this trial is testing

AK104 Plus Radiotherapy Combined With Standard Therapy Versus Standard Therapy as First-Line Treatment for pMMR/MSS CRLM (APSOC)

Who this might be right for
Colorectal Cancer Liver Metastases (CRLM)
Fudan University 73
Testing effectiveness (Phase 2)Looking for participantsNCT07468630
What this trial is testing

Tolecizumab Plus Chemoimmunotherapy for pMMR/MSS Locally Advanced Colon Adenocarcinoma

Who this might be right for
Colon Adenocarcinoma
Daping Hospital and the Research Institute of Surgery of the Third Military Medical University 106
Testing effectiveness (Phase 2)Looking for participantsNCT07279077
What this trial is testing

Node-Sparing Low-Dose Radiotherapy Concurrent With Chemotherapy and PD-1 Inhibitor in pMMR/MSS High-Risk Locally Advanced Colon Cancer: A Prospective, Single-Arm, Phase II Trial

Who this might be right for
Colon CancerNeoadjuvant TherapiesImmune Checkpoint Therapy+1 more
Sixth Affiliated Hospital, Sun Yat-sen University 38
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07007767
What this trial is testing

Exploring Sintilimab + Bevacizumab + Decitabine for Advanced pMMR/MSS Colorectal Cancer (After 2+ Prior Therapies)

Who this might be right for
Colorectal Cancer Metastatic
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 32
Testing effectiveness (Phase 2)Study completedNCT04126733
What this trial is testing

Study on the Effectiveness and Safety of the Combination of the Two Drugs Regorafenib and Nivolumab in Patients With Colorectal Cancer (Cancer of the Colon or Rectum Classified as Proficient Mismatch Repair and Microsatellite Stable)

Who this might be right for
Colorectal Cancer
Bayer 70
Testing effectiveness (Phase 2)Looking for participantsNCT07458529
What this trial is testing

Neoadjuvant Chemoradiotherapy Plus Tislelizumab With or Without Probio-M9 in pMMR/MSS Locally Advanced Rectal Cancer

Who this might be right for
Rectal Cancer, AdenocarcinomaNeoadjuvant TherapyImmunotherapy+3 more
Seventh Medical Center of PLA General Hospital 50
Large-scale testing (Phase 3)Looking for participantsNCT06280495
What this trial is testing

Neoadjuvant Serplulimab & Bevacizumab With FOLFOX vs. FOLFOX Alone in RAS/BRAF WT, pMMR/MSS CRC Patients

Who this might be right for
Colorectal CancerLiver Metastases
Sun Yat-sen University 156
Large-scale testing (Phase 3)Not Yet RecruitingNCT07595276
What this trial is testing

Comparing Efficacy and Safety of Enlituo® Versus Erbitux® Plus FOLFOX in Locally Advanced/Metastatic Colorectal Cancer With RAS/BRAF Wild-type and MSS/pMMR Status.

Who this might be right for
Colorectal Cancer
Taizhou Mabtech Pharmaceutical Co.,Ltd 608
Testing effectiveness (Phase 2)Active Not RecruitingNCT06933251
What this trial is testing

PCSK9 Inhibitor and PD-1 Inhibitor Combined With Neoadjuvant Chemoradiotherapy for pMMR/MSS Locally Advanced Rectal Cancer

Who this might be right for
Locally Advanced Rectal Cancer (LARC)
Guangdong Provincial People's Hospital 30
Testing effectiveness (Phase 2)Looking for participantsNCT06685276
What this trial is testing

Safety and Efficacy of Fruquintinib Plus Chidamide and Sintilimab in the Third and Later Line Treatment of MSS/pMMR Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer Metastatic
Dai, Guanghai 46
Testing effectiveness (Phase 2)Active Not RecruitingNCT05846867
What this trial is testing

A Phase Ib/II Clinical Study on AK112 Combined or Not Combined With AK119 in pMMR/MSS Colorectal Cancer

Who this might be right for
Colorectal Cancer
Akeso 170
Next Page