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Results for “AML With Gene Mutations”

98 trials

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Showing 20 of 98 results

Large-scale testing (Phase 3)Ended earlyNCT02298166
What this trial is testing

Study of Crenolanib in Combination With Chemotherapy in Patients With Relapsed or Refractory Acute Myeloid Leukemia and Activating FLT3 Mutations

Who this might be right for
Acute Myeloid Leukemia
University of Ulm 9
Testing effectiveness (Phase 2)Looking for participantsNCT07507760
What this trial is testing

Oral Decitabine Plus Ivosidenib as First Line for Older/Unfit Adult AML Patients

Who this might be right for
Acute Myeloid Leukemia With Gene Mutations
PETHEMA Foundation 50
Not applicableStudy completedNCT01057199
What this trial is testing

Studying Biomarkers in Cell Samples From Patients With Acute Myeloid Leukemia

Who this might be right for
Leukemia
Children's Oncology Group 6
Early research (Phase 1)Ended earlyNCT04764474
What this trial is testing

HMPL-306 in Advanced Hematological Malignancies With mIDH

Who this might be right for
Isocitrate Dehydrogenase Gene Mutation
Hutchmed 46
Early research (Phase 1)Looking for participantsNCT05735184
What this trial is testing

Investigate the Safety and Tolerability of Ziftomenib in Combination With Venetoclax/Azacitidine, Venetoclax, 7+3, or 7+3+Quizartinib in Patients With AML

Who this might be right for
Acute Myeloid LeukemiaMixed Lineage Leukemia Gene MutationRefractory AML+7 more
Kura Oncology, Inc. 420
Testing effectiveness (Phase 2)UnknownNCT05821738
What this trial is testing

Avapritinib in CBF-AML With KIT Mutations

Who this might be right for
Core Binding Factor Acute Myeloid LeukemiaKIT Mutation-Related Tumors
The First Affiliated Hospital of Soochow University 50
Testing effectiveness (Phase 2)Looking for participantsNCT06561880
What this trial is testing

The Efficacy of Triple Regimen in Newly Diagnosed AML Patients With FLT3 Mutation

Who this might be right for
FLT3 Gene MutationAML
Institute of Hematology & Blood Diseases Hospital, China 66
Testing effectiveness (Phase 2)UnknownNCT03381781
What this trial is testing

Decitabine,Cytarabine and Arsenic Trioxide for Acute Myeloid Leukemia With p53 Mutations

Who this might be right for
Acute Myeloid LeukemiaP53 Mutation
Li Junmin 100
Early research (Phase 1)Study completedNCT02323607
What this trial is testing

Pacritinib and Chemotherapy in Treating Patients With Acute Myeloid Leukemia and FLT3 Mutations

Who this might be right for
Recurrent Adult Acute Myeloid LeukemiaSecondary Acute Myeloid LeukemiaTherapy-Related Acute Myeloid Leukemia+1 more
Bhavana Bhatnagar 13
Testing effectiveness (Phase 2)Looking for participantsNCT03383575
What this trial is testing

Azacitidine and Enasidenib in Treating Patients With IDH2-Mutant Myelodysplastic Syndrome

Who this might be right for
Acute Myeloid LeukemiaBlasts 20-30 Percent of Bone Marrow Nucleated CellsChronic Myelomonocytic Leukemia+4 more
M.D. Anderson Cancer Center 63
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07664839
What this trial is testing

Study on the Efficacy and Safety of VA Regimen Compared to "3+7" Regimen in Newly Diagnosed AML With NPM1 or IDH1/IDH2 Mutations

Who this might be right for
Acute Myeloid LeukemiaNPM1 MutationIDH1 Mutation+1 more
Shen yang 148
Testing effectiveness (Phase 2)Ended earlyNCT01907815
What this trial is testing

Trametinib and Akt Inhibitor GSK2141795 in Treating Patients With Acute Myeloid Leukemia

Who this might be right for
Recurrent Adult Acute Myeloid LeukemiaUntreated Adult Acute Myeloid Leukemia
National Cancer Institute (NCI) 24
Testing effectiveness (Phase 2)Study completedNCT00079482
What this trial is testing

Study of CEP-701 (Lestaurtinib) in Patients With Acute Myeloid Leukemia (AML)

Who this might be right for
Acute Myeloid Leukemia
Cephalon 224
Not applicableStudy completedNCT02986620
What this trial is testing

Italian Registry on the Prevalence of IDH1/IDH2 Mutations in Patients With Acute Myeloid Leukemia

Who this might be right for
AML, Adult
Gruppo Italiano Malattie EMatologiche dell'Adulto 388
Testing effectiveness (Phase 2)Study completedNCT01657682
What this trial is testing

A Phase II Study of Crenolanib in Relapsed/Refractory Acute Myeloid Leukemia Patients With FLT3 Activating Mutations

Who this might be right for
Acute Myeloid Leukemia With FLT3 Activating Mutations That Has Relapsed or Been Refractory After One or More Prior Therapies
Arog Pharmaceuticals, Inc. 56
Not applicableStudy completedNCT03894852
What this trial is testing

SRSF2 Gene Mutation in Patients With t-MDS/AML

Who this might be right for
Therapy Related Myelodysplastic Syndrome and Therapy Related Acute Myeloid Leukemia
Zeinab Albadry Mohammed Zahran 139
Not applicableNo Longer AvailableNCT03409081
What this trial is testing

Early Access Program (EAP) of Gilteritinib (ASP2215) in Patients With FMS-like Tyrosine Kinase 3 (FLT3) Mutated Relapsed or Refractory Acute Myeloid Leukemia (AML) or With FLT3-Mutated AML in Complete Remission (CR) With Minimal Residual Disease (MRD)

Who this might be right for
Acute Myeloid Leukemia (AML)FMS-like Tyrosine Kinase-3 (FLT3) Mutations
Astellas Pharma Global Development, Inc.
Testing effectiveness (Phase 2)Looking for participantsNCT05735717
What this trial is testing

MT2021-08T Cell Receptor Alpha/Beta Depletion PBSC Transplantation for Heme Malignancies

Who this might be right for
Hematologic MalignancyAcute LeukemiaRemission+21 more
Masonic Cancer Center, University of Minnesota 70
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06765915
What this trial is testing

Avapritinib Maintenance for AML With KIT Mutations

Who this might be right for
AML, Adult
Ruijin Hospital 47
Early research (Phase 1)Looking for participantsNCT05756777
What this trial is testing

Gilteritinib in Combination With Ivosidenib or Enasidenib in People With Acute Myeloid Leukemia (AML)

Who this might be right for
Acute Myeloid Leukemia (AML)
Memorial Sloan Kettering Cancer Center 18
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