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Results for “Acute Myeloid Leukemia With Gene Mutations”

94 trials

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Showing 20 of 94 results

Not applicableStudy completedNCT03894852
What this trial is testing

SRSF2 Gene Mutation in Patients With t-MDS/AML

Who this might be right for
Therapy Related Myelodysplastic Syndrome and Therapy Related Acute Myeloid Leukemia
Zeinab Albadry Mohammed Zahran 139
Large-scale testing (Phase 3)Study completedNCT02752035
What this trial is testing

ASP2215 (Gilteritinib) by Itself, ASP2215 Combined With Azacitidine or Azacitidine by Itself to Treat Adult Patients Who Have Recently Been Diagnosed With Acute Myeloid Leukemia With a FLT3 Gene Mutation and Who Cannot Receive Standard Chemotherapy

Who this might be right for
Acute Myeloid Leukemia (AML)Acute Myeloid Leukemia With FMS-like Tyrosine Kinase (FLT3) Mutation
Astellas Pharma Global Development, Inc. 183
Testing effectiveness (Phase 2)WithdrawnNCT03881735
What this trial is testing

Enasidenib in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia With an IDH2 Gene Mutation

Who this might be right for
Blasts Under 5 Percent of Peripheral Blood White CellsBone Marrow Blasts Decreased by 50 Percent or More Compared to Pretreatment LevelIDH2 Gene Mutation+2 more
Roswell Park Cancer Institute
Large-scale testing (Phase 3)Looking for participantsNCT06852222
What this trial is testing

Bleximenib, Venetoclax and Azacitidine For Treatment of Participants With Newly Diagnosed Acute Myeloid Leukemia (AML)

Who this might be right for
Leukemia, Myeloid, Acute
Janssen Research & Development, LLC 600
Not applicableNo Longer AvailableNCT03746912
What this trial is testing

Expanded Treatment Protocol for Adults With FLT3-ITD Mutated Relapsed or Refractory Acute Myeloid Leukemia (AML) to Receive Quizartinib

Who this might be right for
Acute Myeloid Leukemia With Gene Mutations
Daiichi Sankyo
Testing effectiveness (Phase 2)Looking for participantsNCT05904106
What this trial is testing

Venetoclax Plus Azacitidine Versus Intensive Chemotherapy for Fit Patients With Newly Diagnosed NPM1 Mutated AML

Who this might be right for
Acute Myeloid Leukemia
Technische Universität Dresden 146
Testing effectiveness (Phase 2)Looking for participantsNCT04493164
What this trial is testing

CPX-351 and Ivosidenib for the Treatment of IDH1 Mutated Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

Who this might be right for
Acute Myeloid Leukemia With Gene MutationsMyelodysplastic SyndromeMyeloproliferative Neoplasm+2 more
M.D. Anderson Cancer Center 30
Not applicableLooking for participantsNCT07019155
What this trial is testing

Study of Individuals and Families With Aberrations in DDX41 or Similar Cancer Predisposition Variants

Who this might be right for
Germline MutationMyelodysplastic SyndromesAcute Myeloid Leukemia
National Cancer Institute (NCI) 510
Testing effectiveness (Phase 2)Study completedNCT00079482
What this trial is testing

Study of CEP-701 (Lestaurtinib) in Patients With Acute Myeloid Leukemia (AML)

Who this might be right for
Acute Myeloid Leukemia
Cephalon 224
Not applicableApproved For MarketingNCT03070093
What this trial is testing

Expanded Access Study of Gilteritinib (ASP2215) in Patients With FMS-like Tyrosine Kinase 3 (FLT3) Mutated Relapsed or Refractory Acute Myeloid Leukemia (AML) or FLT3-Mutated AML in Complete Remission (CR) With Minimal Residual Disease (MRD)

Who this might be right for
Acute Myeloid Leukemia (AML)FMS-like Tyrosine Kinase-3 (FLT3) Mutations
Astellas Pharma Global Development, Inc.
Not applicableStudy completedNCT03537560
What this trial is testing

Detection of IDH2 Mutations and Monitoring Molecular Residual Disease in Patients With AML

Who this might be right for
Acute Myeloid Leukemia
Chang Gung Memorial Hospital 334
Very early researchEnded earlyNCT03272633
What this trial is testing

Irradiated Donor Cells Following Stem Cell Transplant in Controlling Cancer in Patients With Hematologic Malignancies

Who this might be right for
Acute Lymphoblastic LeukemiaAcute Myeloid Leukemia in RemissionHematopoietic Cell Transplantation Recipient+16 more
Rutgers, The State University of New Jersey 2
Early research (Phase 1)Looking for participantsNCT06366789
What this trial is testing

Dose Escalation and Expansion Study to Evaluate the Safety, PK, PD and Efficacy of ZE46-0134 in Adults With FLT3 Mutated or Spliceosome Mutated Relapsed or Refractory Acute Myeloid Leukemia

Who this might be right for
AML With Gene Mutations
Lomond Therapeutics Holdings, Inc. 150
Not applicableStudy completedNCT01385150
What this trial is testing

Biomarkers in Blood Samples From Patients With Acute Myeloid Leukemia

Who this might be right for
Leukemia
Eastern Cooperative Oncology Group 220
Not applicableLooking for participantsNCT05983991
What this trial is testing

Study for Characterisation of Predictive Parameters of Clonal Evolution in Subjects With GATA2 Germline Mutation

Who this might be right for
GATA2 Gene Mutation
Institut Claudius Regaud 150
Early research (Phase 1)Ended earlyNCT05153330
What this trial is testing

Study of BMF-219, a Covalent Menin Inhibitor, in Adult Patients With AML, ALL (With KMT2A/ MLL1r, NPM1 Mutations), DLBCL, MM, and CLL/SLL

Who this might be right for
Acute Myeloid LeukemiaAcute Lymphoblastic LeukemiaAcute Mixed-Phenotype Leukemia+12 more
Biomea Fusion Inc. 55
Testing effectiveness (Phase 2)Study completedNCT00989261
What this trial is testing

Efficacy Study for AC220 to Treat Acute Myeloid Leukemia (AML)

Who this might be right for
Acute Myeloid Leukemia
Daiichi Sankyo 333
Testing effectiveness (Phase 2)Looking for participantsNCT06778187
What this trial is testing

Oral-ATO for TP53-mutated Myeloid Malignancies

Who this might be right for
Acute Myeloid LeukemiaMyelodysplastic NeoplasmChronic Myelomonocytic Leukemia+2 more
The University of Hong Kong 30
Testing effectiveness (Phase 2)Looking for participantsNCT05735717
What this trial is testing

MT2021-08T Cell Receptor Alpha/Beta Depletion PBSC Transplantation for Heme Malignancies

Who this might be right for
Hematologic MalignancyAcute LeukemiaRemission+19 more
Masonic Cancer Center, University of Minnesota 70
Early research (Phase 1)Study completedNCT00462761
What this trial is testing

A Phase I Study of AC220 in Patients With Relapsed/Refractory Acute Myeloid Leukemia Regardless of FLT3 Status

Who this might be right for
Acute Myeloid LeukemiaLeukemiaMyelodysplastic Syndrome+2 more
Daiichi Sankyo 76
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