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Results for “Advanced or Metastatic NSCLC”

1,069 trials

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Showing 20 of 1,069 results

Testing effectiveness (Phase 2)Looking for participantsNCT07232849
What this trial is testing

A Trial of HRS-4508 Combined With Other Antitumor Therapies in Subjects With Locally Advanced or Metastatic Non-small Cell Lung Cancer

Who this might be right for
Lung Cancer
Jiangsu HengRui Medicine Co., Ltd. 100
Early research (Phase 1)Study completedNCT03811652
What this trial is testing

A Multiple Ascending Dose Study of MEDI7247 in Advanced or Metastatic Solid Tumors

Who this might be right for
Non Small Cell Lung Cancer Squamous (NSCLC-Sq)Head and Neck Squamous Cell Carcinoma (HNSCC)Small Cell Lung Cancer (SCLC)+3 more
MedImmune LLC 8
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07285148
What this trial is testing

Evaluate ANS014004 in Combination With EGFR-TKI in Non-Small Cell Lung Cancer

Who this might be right for
Non-Small Cell Lung CancerEGFR MutationMetastatic Lung Cancer+1 more
Beijing Pearl Biotechnology Limited Liability Company 253
Large-scale testing (Phase 3)UnknownNCT01630733
What this trial is testing

A Multinational, Randomized, Open-Label Study of Custirsen In Patients With Advanced or Metastatic (Stage IV) Non-Small Cell Lung Cancer

Who this might be right for
Non-Small Cell Lung Cancer
Achieve Life Sciences 700
Large-scale testing (Phase 3)Study completedNCT00478049
What this trial is testing

Iressa as Second Line Therapy in Advanced NSCLC-Asia

Who this might be right for
NSCLC
AstraZeneca 163
Testing effectiveness (Phase 2)Active Not RecruitingNCT05445843
What this trial is testing

Study of Efficacy and Safety of JDQ443 Single-agent as First-line Treatment for Patients With Locally Advanced or Metastatic KRAS G12C- Mutated Non-small Cell Lung Cancer With a PD-L1 Expression < 1% or a PD-L1 Expression ≥ 1% and an STK11 Co-mutation.

Who this might be right for
Locally Advanced or Metastatic KRAS G12C-mutated NSCLC With a PD-L1 Expression <1% or a PD-L1 Expression ≥ 1% and an STK11 Co-mutation
Novartis Pharmaceuticals 95
Early research (Phase 1)Study completedNCT01302808
What this trial is testing

Romidepsin and Erlotinib Hydrochloride in Treating Patients With Stage III or Stage IV Non-Small Cell Lung Cancer

Who this might be right for
Lung CancerMetastatic Cancer
University of Texas Southwestern Medical Center 17
Large-scale testing (Phase 3)Study completedNCT05318443
What this trial is testing

A Study Exploring Efficacy of SIBP04 in Subjects With Non-squamous Non-small Cell Lung Cancer

Who this might be right for
Non-squamous Non-small-cell Lung Cancer
Shanghai Institute Of Biological Products 512
Early research (Phase 1)Study completedNCT02457793
What this trial is testing

The Safety, Tolerability, and Effects of Cobimetinib and GDC-0994 in Patients With Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Non-Small Cell Lung Cancer, Metastatic Colorectal Cancer, Metastatic Non Small Cell Lung Cancer, Metastatic Cancers, Melanoma
Genentech, Inc. 24
Testing effectiveness (Phase 2)Looking for participantsNCT06567015
What this trial is testing

Study of FIH of STX-241 in Locally Advanced or Metastatic NSCLC Resistant to EGFR TKIs

Who this might be right for
Non-small Cell Lung Cancer (NSCLC)
Pierre Fabre Medicament 171
Testing effectiveness (Phase 2)Study completedNCT00940225
What this trial is testing

Study of Cabozantinib (XL184) in Adults With Advanced Malignancies

Who this might be right for
Solid TumorsCancer
Exelixis 730
Testing effectiveness (Phase 2)Study completedNCT01721759
What this trial is testing

Study of Nivolumab (BMS-936558) in Patients With Advanced or Metastatic Squamous Cell Nonsmall-cell Lung Cancer Who Have Received At Least 2 Prior Systemic Regimens

Who this might be right for
Squamous Cell Non-small Cell Lung Cancer
Bristol-Myers Squibb 117
Large-scale testing (Phase 3)Active Not RecruitingNCT04765059
What this trial is testing

Evaluate Chemotherapy Plus Osimertinib Against Chemotherapy Plus Placebo in Patients With Non-small Cell Lung Cancer (NSCLC)

Who this might be right for
Non-small Cell Lung Cancer
AstraZeneca 98
Early research (Phase 1)Active Not RecruitingNCT02495896
What this trial is testing

Recombinant EphB4-HSA Fusion Protein With Standard Chemotherapy Regimens in Treating Patients With Advanced or Metastatic Solid Tumors

Who this might be right for
Head and Neck Squamous Cell CarcinomaMetastatic Pancreatic AdenocarcinomaNon-Resectable Cholangiocarcinoma+13 more
University of Southern California 61
Large-scale testing (Phase 3)Looking for participantsNCT06357533
What this trial is testing

Phase III, Open-label, Study of First-line Dato-DXd in Combination With Rilvegostomig for Advanced Non-squamous NSCLC With High PD-L1 Expression (TC ≥ 50%) and Without Actionable Genomic Alterations

Who this might be right for
Non-Small Cell Lung Cancer
AstraZeneca 675
Testing effectiveness (Phase 2)Looking for participantsNCT06172478
What this trial is testing

HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Advanced Solid TumorMelanomaHead and Neck Cancer+11 more
Daiichi Sankyo 740
Early research (Phase 1)Active Not RecruitingNCT05653882
What this trial is testing

A Study Evaluating AB248 Alone or in Combination With Pembrolizumab in Adult Patients With Solid Tumors

Who this might be right for
Solid TumorNon Small Cell Lung CancerMelanoma+2 more
Asher Biotherapeutics, Inc. 552
Large-scale testing (Phase 3)Study completedNCT00441740
What this trial is testing

Randomized Trial With Vinorelbine and Gemcitabine Versus Docetaxel and Gemcitabine in Patients With Non-Small Cell Lung Cancer

Who this might be right for
Non Small Cell Lung Cancer
Hellenic Oncology Research Group 419
Not applicableLooking for participantsNCT07028489
What this trial is testing

Prospective External Control Cohort In Patients With Newly Diagnosed Advanced or Metastatic EGFR Mutant Non-Small Cell Lung Cancer

Who this might be right for
Non Small Cell Lung Cancer
N-Power Medicine 130
Large-scale testing (Phase 3)Looking for participantsNCT07174908
What this trial is testing

IN10018 in Combination With D-1553 Versus Standard Therapy for First Line Non-squamous Non-small Cell Lung Cancer With KRAS G12C Mutation

Who this might be right for
Non-Small Cell Lung Cancer
InxMed (Shanghai) Co., Ltd. 400
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