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Results for “Alpha 1-proteinase Inhibitor Deficiency”

141 trials

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Showing 20 of 141 results

Post-approval studies (Phase 4)WithdrawnNCT04440488
What this trial is testing

ARALAST NP Alpha-1 Lung Density Chronic Obstructive Pulmonary Disease-Emphysema (COPD-E) Study

Who this might be right for
Chronic Obstructive Pulmonary DiseaseAlpha1-antitrypsin Deficiency
Shire
Large-scale testing (Phase 3)Study completedNCT00460096
What this trial is testing

Phase II/III Study of an Alpha-1 Proteinase Inhibitor (Kamada-API) in Individuals With Alpha-1 Antitrypsin Deficiency

Who this might be right for
Alpha 1-Antitrypsin Deficiency
Kamada, Ltd. 50
Not applicableStudy completedNCT03188601
What this trial is testing

Α1-antitrypsin (AAT) Levels and Functions in Allogeneic Bone Marrow Transplantation and Throughout Progression Into GVHD

Who this might be right for
GVHDBone Marrow Transplant FailureAlpha 1-Antitrypsin
Rambam Health Care Campus 27
Large-scale testing (Phase 3)Enrolling By InvitationNCT02796937
What this trial is testing

Long Term Safety of Alpha1-Proteinase Inhibitor in Subjects With Alpha1 Antitrypsin Deficiency

Who this might be right for
Pulmonary Emphysema in Alpha-1 Antitrypsin Deficiency
Grifols Therapeutics LLC 290
Early research (Phase 1)Looking for participantsNCT06049082
What this trial is testing

KB408 for the Treatment of Alpha-1 Antitrypsin Deficiency

Who this might be right for
Alpha 1-Antitrypsin Deficiency
Krystal Biotech, Inc. 15
Not applicableUnknownNCT03285100
What this trial is testing

The Effects of Discontinuation of Vitamin K Antagonists on the Rate of Elastin Degradation

Who this might be right for
Emphysema or COPDAneurysmCystic Fibrosis+1 more
Canisius-Wilhelmina Hospital 30
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07227207
What this trial is testing

TSRA-196 in Adults With PiZZ Alpha-1 Antitrypsin Deficiency (AATD)

Who this might be right for
Alpha-1 Antitrypsin Deficiency (AATD)
Tessera Therapeutics, Inc. 72
Testing effectiveness (Phase 2)Study completedNCT02168686
What this trial is testing

Safety Dose Finding Study of ADVM-043 Gene Therapy to Treat Alpha-1 Antitrypsin (A1AT) Deficiency

Who this might be right for
Alpha 1-Antitrypsin Deficiency
Adverum Biotechnologies, Inc. 6
Testing effectiveness (Phase 2)Study completedNCT03679598
What this trial is testing

Alvelestat (MPH966) for the Treatment of ALpha-1 ANTitrypsin Deficiency

Who this might be right for
Alpha-1 Antitrypsin Deficiency (AATD)Pi*ZZ, Pi*SZ, Pi*Null, Another Rare Phenotype/Genotype Known to be Associated With Either Low or Functionally Impaired AAT Including F or I MutationsEmphysema or COPD
University of Alabama at Birmingham 63
Not applicableStudy completedNCT00499941
What this trial is testing

Alpha-1 Foundation Research Registry

Who this might be right for
Alpha 1-Antitrypsin Deficiency
Medical University of South Carolina 6,655
Testing effectiveness (Phase 2)Study completedNCT02870309
What this trial is testing

Safety and Pharmacokinetics of Alpha-1 MP (Alpha1-proteinase Inhibitor (Human), Modified Process) in Participants With Alpha1-Antitrypsin Deficiency

Who this might be right for
Alpha1-Antitrypsin Deficiency
Grifols Therapeutics LLC 4
Not applicableEnrolling By InvitationNCT06892236
What this trial is testing

Preparation of IPSC for Cell Gene Editing for the Treatment of AATD

Who this might be right for
Alpha1-antitrypsin Deficiency
Fondazione IRCCS Policlinico San Matteo di Pavia 3
Early research (Phase 1)Study completedNCT00430768
What this trial is testing

Experimental Gene Transfer Procedure to Treat Alpha 1-Antitrypsin (AAT) Deficiency

Who this might be right for
Alpha 1-Antitrypsin Deficiency
University of Massachusetts, Worcester 9
Early research (Phase 1)Study completedNCT00242385
What this trial is testing

Pharmacokinetic Study of ARALAST (Human Alpha1- PI)

Who this might be right for
Alpha 1-Antitrypsin Deficiency
Baxalta now part of Shire 25
Post-approval studies (Phase 4)Study completedNCT00670007
What this trial is testing

Extension Study of Zemaira® i.v. Administration in Subjects With Emphysema Due to alpha1-proteinase Inhibitor Deficiency.

Who this might be right for
EmphysemaAlpha 1-proteinase Inhibitor Deficiency
CSL Behring 140
Not applicableLooking for participantsNCT00500123
What this trial is testing

The Alpha-1 Foundation's and University of Florida's Alpha-1 Coded Testing (ACT) Study

Who this might be right for
Alpha-1 Antitrypsin Deficiency
University of Florida 50,000
Early research (Phase 1)Ended earlyNCT02363946
What this trial is testing

ARC-AAT in Healthy Volunteer Subjects and Patients With Alpha-1 Antitrypsin Deficiency (AATD)

Who this might be right for
Alpha-1 Antitrypsin Deficiency
Arrowhead Pharmaceuticals 65
Testing effectiveness (Phase 2)Study completedNCT00263887
What this trial is testing

Alpha-1-Antitrypsin (AAT) To Treat Emphysema In AAT-Deficient Patients (EXACTLE)

Who this might be right for
Alpha 1-Antitrypsin Deficiency
Grifols Therapeutics LLC 77
Testing effectiveness (Phase 2)Study completedNCT00067756
What this trial is testing

4-PBA: Will it Increase the Level of Alpha 1-Antitrypsin(AAT) in Persons With AAT Deficiency?

Who this might be right for
Alpha 1-Antitrypsin Deficiency
University of Florida 12
Testing effectiveness (Phase 2)Study completedNCT05856331
What this trial is testing

Study of SAR447537 (INBRX-101) Compared to Plasma-derived A1PI Therapy in Adults With AATD Emphysema

Who this might be right for
Alpha 1-Antitrypsin DeficiencyEmphysema
Sanofi 99
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