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Results for “Alpha-1 Antitrypsin Deficiency (AATD)”

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Showing 20 of 0 results

Testing effectiveness (Phase 2)Study completedNCT02870309
What this trial is testing

Safety and Pharmacokinetics of Alpha-1 MP (Alpha1-proteinase Inhibitor (Human), Modified Process) in Participants With Alpha1-Antitrypsin Deficiency

Who this might be right for
Alpha1-Antitrypsin Deficiency
Grifols Therapeutics LLC 4
Testing effectiveness (Phase 2)WithdrawnNCT02900183
What this trial is testing

Safety, Tolerability and Effect of ARC-AAT Injection on Circulating and Intrahepatic Alpha-1 Antitrypsin Levels

Who this might be right for
Alpha-1 Antitrypsin Deficiency
Arrowhead Pharmaceuticals
Not applicableLooking for participantsNCT01851642
What this trial is testing

Lung Disease and Its Affect on the Work of White Blood Cells in the Lungs

Who this might be right for
Alpha-1 Antitrypsin DeficiencyAAT DeficiencyAATD+1 more
University of Florida 220
Not applicableUnknownNCT04966221
What this trial is testing

Functional and Structural Lung Imaging in Chronic Obstructive Pulmonary Disease

Who this might be right for
Chronic Obstructive Pulmonary DiseaseAlpha 1-Antitrypsin Deficiency
University of Nottingham 75
Not applicableStudy completedNCT01419158
What this trial is testing

Prevalence of Alpha-1 Antitrypsin Deficiency in Chronic Obstructive Pulmonary Disease (COPD)

Who this might be right for
Alpha-1 Antitrypsin DeficiencyChronic Obstructive Pulmonary Disease
Alpha-1 Foundation 3,457
Testing effectiveness (Phase 2)Ended earlyNCT02093221
What this trial is testing

Study of Human Plasma-Derived Alpha1-Proteinase Inhibitor in Subjects With New-Onset Type 1 Diabetes Mellitus

Who this might be right for
Type 1 Diabetes Mellitus
Grifols Therapeutics LLC 76
Very early researchStudy completedNCT00377416
What this trial is testing

Experimental Gene Transfer Procedure to Treat Alpha 1-Antitrypsin Deficiency

Who this might be right for
Alpha 1-Antitrypsin Deficiency
University of Massachusetts, Worcester 12
Testing effectiveness (Phase 2)Study completedNCT03946449
What this trial is testing

Study of Fazirsiran (TAK-999, ARO-AAT) in Patients With Alpha-1 Antitrypsin Deficiency Associated Liver Disease (AATD)

Who this might be right for
Alpha 1-Antitrypsin Deficiency
Arrowhead Pharmaceuticals 16
Testing effectiveness (Phase 2)Ended earlyNCT06677307
What this trial is testing

A Phase 1/2a, Single- and Multiple-dose Escalation Study of KRRO-110

Who this might be right for
Alpha-1 Anti-trypsin DeficiencyAATD
Korro Bio, Inc. 42
Testing effectiveness (Phase 2)Ended earlyNCT01379469
What this trial is testing

Carbamazepine in Severe Liver Disease Due to Alpha-1 Antitrypsin Deficiency

Who this might be right for
Alpha-1-antitrypsin DeficiencyLiver Cirrhosis
Washington University School of Medicine 20
Not applicableStudy completedNCT00005292
What this trial is testing

Alpha1-antitrypsin Deficiency Registry

Who this might be right for
Lung DiseasesEmphysemaAlpha-1 Antitrypsin Deficiency+1 more
National Heart, Lung, and Blood Institute (NHLBI)
Post-approval studies (Phase 4)Study completedNCT00670007
What this trial is testing

Extension Study of Zemaira® i.v. Administration in Subjects With Emphysema Due to alpha1-proteinase Inhibitor Deficiency.

Who this might be right for
EmphysemaAlpha 1-proteinase Inhibitor Deficiency
CSL Behring 140
Not applicableLooking for participantsNCT00001532
What this trial is testing

Role of Genetic Factors in the Development of Lung Disease

Who this might be right for
Cystic FibrosisPulmonary FibrosisTuberous Sclerosis+2 more
National Heart, Lung, and Blood Institute (NHLBI) 3,500
Not applicableEnded earlyNCT00005098
What this trial is testing

Study of Genotype and Phenotype in Patients With Alpha 1-Antitrypsin Deficiency

Who this might be right for
Alpha 1-Antitrypsin Deficiency
National Center for Research Resources (NCRR) 160
Not applicableStudy completedNCT01862211
What this trial is testing

Polygen Defi-Alpha: Genetic Polymorphisms Study in Children With Alpha-1 Antitrypsin Deficiency, Included in the DEFI-ALPHA Cohort

Who this might be right for
Children With a Deficiency of Alpha-1 Antitrypsin
Hospices Civils de Lyon 296
Early research (Phase 1)Looking for participantsNCT07431112
What this trial is testing

AIR-001 in Adults With Alpha-1 Antitrypsin Deficiency (AATD)

Who this might be right for
Alpha 1 Antitrypsin Deficiency
AIRNA Corporation 54
Early research (Phase 1)Study completedNCT05579431
What this trial is testing

A Phase 1, First-in-human Study of VX-634

Who this might be right for
Alpha 1-Antitrypsin Deficiency
Vertex Pharmaceuticals Incorporated 127
Early research (Phase 1)Study completedNCT03815396
What this trial is testing

Phase 1 Study to Assess the Safety, PK and PD of INBRX-101 in Adults With Alpha-1 Antitrypsin Deficiency

Who this might be right for
Alpha-1 Antitrypsin DeficiencyAATD
Inhibrx Biosciences, Inc 31
Large-scale testing (Phase 3)Looking for participantsNCT05677971
What this trial is testing

Study to Check the Safety of Fazirsiran and Learn if Fazirsiran Can Help People With Liver Disease and Scarring (Fibrosis) Due to an Abnormal Version of Alpha-1 Antitrypsin Protein

Who this might be right for
Alpha1-Antitrypsin Deficiency
Takeda 160
Large-scale testing (Phase 3)Study completedNCT00460096
What this trial is testing

Phase II/III Study of an Alpha-1 Proteinase Inhibitor (Kamada-API) in Individuals With Alpha-1 Antitrypsin Deficiency

Who this might be right for
Alpha 1-Antitrypsin Deficiency
Kamada, Ltd. 50
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