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Results for “Ataxia-Telangiectasia (A-T)”

60 trials

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Showing 20 of 60 results

Post-approval studies (Phase 4)Study completedNCT00950196
What this trial is testing

Amantadine for Improving Neurologic Symptoms in Ataxia-Telangiectasia

Who this might be right for
AtaxiaChoreaDystonia+2 more
Sheba Medical Center 30
Testing effectiveness (Phase 2)Looking for participantsNCT05010031
What this trial is testing

Reduced-dose Radiation in People With Metastatic Tumors With a Genetic Change

Who this might be right for
Metastatic Cancer
Memorial Sloan Kettering Cancer Center 45
Not applicableUnknownNCT00951886
What this trial is testing

The Validity of Forced Expiratory Maneuvers in Ataxia Telangiectasia Studied Longitudinally

Who this might be right for
Ataxia Telangiectasia
Sheba Medical Center 28
Early research (Phase 1)Study completedNCT04095273
What this trial is testing

Study to Test How Well Patients With Advanced Solid Tumors Respond to Treatment With the Elimusertib in Combination With Pembrolizumab, to Find the Optimal Dose for Patients, How the Drug is Tolerated and the Way the Body Absorbs, Distributes and Discharges the Drug

Who this might be right for
Advanced Solid Tumors
Bayer 56
Not applicableStudy completedNCT05252819
What this trial is testing

Whole Body MRI for Cancer Surveillance in A-T

Who this might be right for
Ataxia Telangiectasia
University of Nottingham 32
Very early researchStudy completedNCT00640003
What this trial is testing

Baclofen Treatment of Ataxia Telangiectasia

Who this might be right for
Ataxia Telangiectasia
Johns Hopkins University 10
Testing effectiveness (Phase 2)Looking for participantsNCT07371663
What this trial is testing

An Phase Ib/II Clinical Trial of TCC1727 Combination Therapy in Advanced Solid Tumors

Who this might be right for
Solid CancersNSCLC (Advanced Non-small Cell Lung Cancer)Gastric (Stomach) Cancer+2 more
Beijing Tide Pharmaceutical Co., Ltd 266
Large-scale testing (Phase 3)Looking for participantsNCT02000089
What this trial is testing

The Cancer of the Pancreas Screening-5 CAPS5)Study

Who this might be right for
Pancreas CancerPeutz-Jeghers Syndrome (PJS)Gene Mutation+2 more
Johns Hopkins University 9,000
Not applicableStudy completedNCT01942850
What this trial is testing

International Ataxia Rating Scale in Younger Patients

Who this might be right for
Ataxia Telangiectasia
Quince Therapeutics S.p.A. 63
Not applicableWithdrawnNCT02309632
What this trial is testing

Pancreatic Cancer Screening of High-Risk Individuals in Arkansas

Who this might be right for
Pancreatic NeoplasmsPeutz-Jegher's SyndromeBRCA1 Gene Mutation+5 more
University of Arkansas
Large-scale testing (Phase 3)Active Not RecruitingNCT06673056
What this trial is testing

A Pivotal Study of N-Acetyl-L-Leucine on Ataxia-Telangiectasia (A-T)

Who this might be right for
Ataxia-TelangiectasiaAtaxia-Telangiectasia (A-T)
IntraBio Inc 60
Not applicableActive Not RecruitingNCT05692596
What this trial is testing

The Pancreas Interception Center (PIC) for Early Detection, Prevention, and Novel Therapeutics

Who this might be right for
Pancreatic Ductal AdenocarcinomaPancreatic CystChronic Pancreatitis+10 more
H. Lee Moffitt Cancer Center and Research Institute 317
Large-scale testing (Phase 3)Study completedNCT02770807
What this trial is testing

Intra-Erythrocyte Dexamethasone Sodium Phosphate in Ataxia Telangiectasia Patients

Who this might be right for
Nervous System DiseaseGenetic Syndrome
Quince Therapeutics S.p.A. 176
Testing effectiveness (Phase 2)Study completedNCT03962114
What this trial is testing

Effects of Vitamin B3 in Patients With Ataxia Telangiectasia

Who this might be right for
Ataxia TelangiectasiaATM Gene Mutation
Radboud University Medical Center 24
Testing effectiveness (Phase 2)Study completedNCT04564027
What this trial is testing

A Study Investigating DNA-damage Response Agents in Molecularly Altered Advanced Cancer

Who this might be right for
Advanced Solid Tumours
AstraZeneca 54
Not applicableUnknownNCT06324877
What this trial is testing

Ataxia-telangiectasia: Treating Mitochondrial Dysfunction With Nicotinamide Riboside

Who this might be right for
Ataxia Telangiectasia
The University of Queensland 10
Not applicableUnknownNCT04991701
What this trial is testing

A National Retrospective Population Based Cohort Study of the Natural History of Ataxia Telangiectasia

Who this might be right for
Ataxia Telangiectasia
University of Nottingham 178
Early research (Phase 1)Study completedNCT06308263
What this trial is testing

Tuvusertib (M1774) Human Mass Balance and Absolute Bioavailability Study (DDRIVER Solid Tumors 303)

Who this might be right for
Solid Tumor
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany 12
Testing effectiveness (Phase 2)Looking for participantsNCT07215416
What this trial is testing

Safety and Efficacy of Mutation-targeted Precision Genetic Therapy for Ataxia-Telangiectasia (A-T)

Who this might be right for
Ataxia Telangiectasia
Timothy Yu 10
Not applicableUnknownNCT04037189
What this trial is testing

Treatment of Leukemia and Lymphoma in Children With Ataxia Telangiectasia

Who this might be right for
Ataxia TelangiectasiaLeukemiaLymphoma
Rabin Medical Center 250
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