Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “BRCA1 Mutation Carrier”

58 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 58 results

Testing effectiveness (Phase 2)UnknownNCT00080756
What this trial is testing

Deslorelin Combined With Low-Dose Add-Back Estradiol and Testosterone in Preventing Breast Cancer in Premenopausal Women Who Are at High Risk for This Disease

Who this might be right for
brca1 Mutation Carrierbrca2 Mutation CarrierBreast Cancer
City of Hope Medical Center 11
Testing effectiveness (Phase 2)Active Not RecruitingNCT02571725
What this trial is testing

PARP-inhibition and CTLA-4 Blockade in BRCA-deficient Ovarian Cancer

Who this might be right for
Ovarian CancerFallopian Tube CancerPeritoneal Neoplasms
New Mexico Cancer Research Alliance 50
Early research (Phase 1)Study completedNCT01154426
What this trial is testing

ABT-888 and Gemcitabine Hydrochloride in Treating Patients With Advanced Solid Tumors

Who this might be right for
Adult Solid NeoplasmBRCA1 Mutation CarrierBRCA2 Mutation Carrier
National Cancer Institute (NCI) 31
Large-scale testing (Phase 3)Active Not RecruitingNCT01905046
What this trial is testing

Metformin Hydrochloride in Preventing Breast Cancer in Patients With Atypical Hyperplasia or In Situ Breast Cancer

Who this might be right for
Atypical Ductal Breast HyperplasiaBRCA1 Mutation CarrierBRCA2 Mutation Carrier+2 more
Alliance for Clinical Trials in Oncology 86
Early research (Phase 1)Study completedNCT00892736
What this trial is testing

Veliparib in Treating Patients With Malignant Solid Tumors That Do Not Respond to Previous Therapy

Who this might be right for
Basal-Like Breast CarcinomaBRCA1 Mutation CarrierBRCA2 Mutation Carrier+14 more
National Cancer Institute (NCI) 98
Testing effectiveness (Phase 2)Study completedNCT01540565
What this trial is testing

Veliparib in Treating Patients With Persistent or Recurrent Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Who this might be right for
BRCA1 Mutation CarrierBRCA2 Mutation CarrierOvarian Epithelial Tumor+3 more
National Cancer Institute (NCI) 52
Not applicableStudy completedNCT03066856
What this trial is testing

Dietary Intervention and BRCA Penetrance

Who this might be right for
Dietary ModificationBRCA1 MutationBRCA2 Mutation+1 more
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano 502
Testing effectiveness (Phase 2)Study completedNCT01506609
What this trial is testing

Study Evaluating Efficacy And Tolerability Of Veliparib in Combination With Temozolomide (TMZ) or In Combination With Carboplatin and Paclitaxel Versus Placebo in Participants With Breast Cancer Gene (BRCA)1 and BRCA2 Mutation and Metastatic Breast Cancer

Who this might be right for
Metastatic Breast Cancer
AbbVie 294
Not applicableLooking for participantsNCT02705846
What this trial is testing

Analysing Outcomes After Prostate Cancer Diagnosis and Treatment in Carriers of Rare Germline Mutations

Who this might be right for
Prostate Cancer
Institute of Cancer Research, United Kingdom 4,260
Not applicableStudy completedNCT03684733
What this trial is testing

Magnetic Resonance Breast Tissue Characterisation to Improve Risk Stratification for Breast Cancer

Who this might be right for
BRCA1 MutationBRCA2 MutationMammography+1 more
Royal Marsden NHS Foundation Trust 28
Post-approval studies (Phase 4)Study completedNCT03495609
What this trial is testing

Use of Recombinant hCG to Prevent Breast Cancer in BRCA1 and BRCA2 Carriers

Who this might be right for
hCGBRCA1 MutationBRCA2 Mutation
University Hospital, Ghent 33
Very early researchEnded earlyNCT03382574
What this trial is testing

Pilot Study of Denosumab in BRCA1/2 Mutation Carriers Scheduled for Risk-Reducing Salpingo-Oophorectomy

Who this might be right for
Ovarian Carcinoma
National Cancer Institute (NCI) 2
Early research (Phase 1)Active Not RecruitingNCT02208375
What this trial is testing

MTORC1/2 Inhibitor AZD2014 or the Oral AKT Inhibitor AZD5363 for Recurrent Endometrial and Ovarian

Who this might be right for
BRCA1 Mutation CarrierBRCA2 Mutation CarrierEndometrial Adenocarcinoma+13 more
M.D. Anderson Cancer Center 159
Testing effectiveness (Phase 2)Study completedNCT01009788
What this trial is testing

ABT-888 and Temozolomide for Metastatic Breast Cancer and BRCA1/2 Breast Cancer

Who this might be right for
Breast CancerMetastatic Breast CancerBRCA1 Gene Mutation+1 more
Steven J Isakoff, MD, PhD 63
Not applicableWithdrawnNCT01409226
What this trial is testing

3.0 Tesla Magnetic Resonance Imaging for Breast Cancer Detection in High Risk Women

Who this might be right for
Breast CancerBRCA1 MutationBRCA2 Mutation
NYU Langone Health
Early research (Phase 1)Study completedNCT01445418
What this trial is testing

AZD2281 Plus Carboplatin to Treat Breast and Ovarian Cancer

Who this might be right for
Breast CancerOvarian Cancer
National Cancer Institute (NCI) 103
Early research (Phase 1)Active Not RecruitingNCT04367675
What this trial is testing

INO 5401 Vaccination in BRCA1/2 Mutation Carriers

Who this might be right for
BRCA1/2 Mutation
Abramson Cancer Center at Penn Medicine 44
Not applicableStudy completedNCT02608346
What this trial is testing

Circulating Tumor DNA and Follow-up of BRCA1 Mutation Carriers (CirCa 01)

Who this might be right for
Women With BRCA1 Germline Deleterious Mutation
Institut Curie 200
Not applicableStudy completedNCT02087592
What this trial is testing

Feasibility of Lifestyle Intervention in BRCA1/2 Mutation Carriers

Who this might be right for
Hereditary Breast and Ovarian Cancer
Technical University of Munich 69
Not applicableWithdrawnNCT00084370
What this trial is testing

Celecoxib in Preventing Cancer in Patients at High Risk for Ovarian Epithelial Cancer Who Are Undergoing Prophylactic Oophorectomy

Who this might be right for
brca1 Mutation Carrierbrca2 Mutation CarrierOvarian Cancer
University of Alabama at Birmingham
Next Page