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Results for “Belumosudil”

30 trials

Showing 20 of 30 results

Not applicableLooking for participantsNCT07794514
What this trial is testing

Belumosudil Versus Ruxolitinib for Steroid-Refractory or Breakthrough Hepatic cGVHD

Who this might be right for
Hematopoietic Stem Cell Transplantation (HSCT)cGVHDHepatic cGVHD+2 more
First Affiliated Hospital of Zhejiang University 170
Large-scale testing (Phase 3)Active Not RecruitingNCT06143891
What this trial is testing

Test an Oral Medicine, Belumosudil, in Combination With Corticosteroids in Participants at Least 12 Years of Age With Newly Diagnosed Chronic Graft Versus Host Disease.

Who this might be right for
Chronic Graft Versus Host Disease
Sanofi 260
Post-approval studies (Phase 4)Study completedNCT06616415
What this trial is testing

A Clinical Study to Evaluate the Pharmacokinetics, Efficacy, and Safety of Belumosudil in Chinese Adolescents With cGVHD Who Have Had an Inadequate Response to Glucocorticoids or Other Systemic Therapies

Who this might be right for
Chronic Graft Versus Host Disease
Sanofi 6
Large-scale testing (Phase 3)Looking for participantsNCT06082037
What this trial is testing

Test How Effective Belumosudil Tablets Are for Treating Adult Participants With Chronic Lung Allograft Dysfunction

Who this might be right for
Lung Transplant Rejection
Sanofi 180
Post-approval studies (Phase 4)Not Yet RecruitingNCT07135973
What this trial is testing

Investigate Safety of Belumosudil in Participants Aged 12 Years and Above, With Chronic Graft-versus-host Disease (cGVHD)

Who this might be right for
Chronic Graft Versus Host Disease
Sanofi 26
Early research (Phase 1)Study completedNCT02557139
What this trial is testing

Bioavailability of Belumosudil (KD025) in Healthy Male Subjects

Who this might be right for
Bioavailability
Kadmon Corporation, LLC 23
Testing effectiveness (Phase 2)WithdrawnNCT05567406
What this trial is testing

Safety and Efficacy of Oral Belumosudil in Black or African American, American Indian or Alaska Native, and Native Hawaiian or Other Pacific Islander Male and Female Participants Aged 12 Years and Above With Chronic Graft Versus Host Disease (cGVHD) After At Least 2 Prior Lines of Systemic Therapy

Who this might be right for
Chronic Graft Versus Host Disease
Kadmon, a Sanofi Company
Early research (Phase 1)Not Yet RecruitingNCT07484113
What this trial is testing

IL6-receptor Inhibitor Iwith Belumosudil for the Treatment of Belumosudil-refractory cGVHD

Who this might be right for
cGVHD
Stanford University 10
Testing effectiveness (Phase 2)Ended earlyNCT03919799
What this trial is testing

KD025 in Subjects With Diffuse Cutaneous Systemic Sclerosis

Who this might be right for
System; SclerosisDiffuse Cutaneous Systemic Sclerosis
Kadmon, a Sanofi Company 36
Early research (Phase 1)Study completedNCT03530995
What this trial is testing

Drug-drug Interaction Between Belumosudil, Itraconazole, Rifampicin, Rabeprazole, and Omeprazole in Healthy Volunteers

Who this might be right for
Drug-drug InteractionAutoimmune DiseasesFibrotic Disease
Kadmon Corporation, LLC 73
Testing effectiveness (Phase 2)Looking for participantsNCT06105554
What this trial is testing

Phase I/II Open Label Study of Belumosudil Mesylate Alone, and in Combination With Dexamethasone, in Patients With Relapsed/Refractory Multiple Myeloma

Who this might be right for
Multiple Myeloma
M.D. Anderson Cancer Center 36
Early research (Phase 1)Not Yet RecruitingNCT07726914
What this trial is testing

Study to Compare the Plasma Concentration of Belumosudil Given as an Oral Suspension and as a Tablet to Healthy Adult Male Participants

Who this might be right for
Chronic Graft Versus Host Disease
Sanofi 58
Testing effectiveness (Phase 2)Enrolling By InvitationNCT06751602
What this trial is testing

Belumosudil for Abrogation of Interstitial Fibrosis and Tubular Atrophy Following Kidney Transplantation

Who this might be right for
Rejection Chronic Renal
The Methodist Hospital Research Institute 40
Very early researchStudy completedNCT04735822
What this trial is testing

A Phase I Study to Evaluate the Taste of Belumosudil Oral Suspensions & Assess Relative Bioavailability

Who this might be right for
Healthy Volunteers
Kadmon Corporation, LLC 30
Early research (Phase 1)Study completedNCT05806567
What this trial is testing

Assess the Effect of Oral Belumosudil on Inhibition of Various Proteins in the Fed State in Healthy Male Subjects

Who this might be right for
Immune System DisorderHealthy Volunteers
Kadmon, a Sanofi Company 52
Testing effectiveness (Phase 2)Looking for participantsNCT06046248
What this trial is testing

Belumosudil and Rituximab for Primary Treatment of Chronic Graft-Versus-Host-Disease

Who this might be right for
Chronic Graft Versus Host Disease
Northside Hospital, Inc. 25
Testing effectiveness (Phase 2)Study completedNCT02852967
What this trial is testing

A Phase 2, Double-blind, Placebo-controlled Study of the Efficacy and Safety of Belumosudil in Subjects With Moderate/Severe Chronic Plaque Psoriasis

Who this might be right for
Chronic Plaque Psoriasis
Kadmon Corporation, LLC 110
Testing effectiveness (Phase 2)Study completedNCT05305989
What this trial is testing

Extended Treatment and Follow-up of Subjects Treated With Belumosudil in Study KD025-208 or Study KD025-213

Who this might be right for
Chronic Graft-versus-host-disease
Kadmon, a Sanofi Company 23
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07643025
What this trial is testing

Belumosudil With Ruxolitnib as Second Line Therapy for Chronic Graft Versus Host Disease (cGvHD) After Steroid Failure

Who this might be right for
cGVHD
Dennis Kim 63
Large-scale testing (Phase 3)Not Yet RecruitingNCT07771439
What this trial is testing

Investigate the Efficacy and Safety of Belumosudil Compared With Best Available Therapy in Participants Aged 12 Years or Older With Chronic Graft-versus-host Disease

Who this might be right for
Chronic Graft Versus Host Disease
Sanofi 356
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