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Results for “C3G”

33 trials

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Showing 20 of 33 results

Large-scale testing (Phase 3)Study completedNCT05067127
What this trial is testing

Phase III Study Assessing the Efficacy and Safety of Pegcetacoplan in Patients With C3 Glomerulopathy or Immune-Complex Membranoproliferative Glomerulonephritis

Who this might be right for
C3GIC-MPGNC3 Glomerulopathy+9 more
Apellis Pharmaceuticals, Inc. 124
Large-scale testing (Phase 3)Looking for participantsNCT05795140
What this trial is testing

Evaluate Long-term Safety, Tolerability and Efficacy of Iptacopan in Study Participants With aHUS

Who this might be right for
Atypical Hemolytic Uremic Syndrome
Novartis Pharmaceuticals 125
Not applicableNot Yet RecruitingNCT07331259
What this trial is testing

CHART-C3G/CLNP023B12011

Who this might be right for
C3 GlomerulopathyComplement-mediated Kidney DiseaseProteinuria
Novartis Pharmaceuticals 83
Not applicableLooking for participantsNCT07029542
What this trial is testing

Home Reported Outcomes in C3G Study

Who this might be right for
C3 Glomerulopathy
Novartis Pharmaceuticals 100
Not applicableActive Not RecruitingNCT05985122
What this trial is testing

New Analytic Tools for aHUS and C3G Diagnosis

Who this might be right for
Hemolytic-Uremic SyndromeMembranoproliferative GlomerulonephritisHealthy
Mario Negri Institute for Pharmacological Research 180
Testing effectiveness (Phase 2)Study completedNCT03301467
What this trial is testing

Controlled Trial Evaluating Avacopan in C3 Glomerulopathy

Who this might be right for
C3 Glomerulopathy (C3G)
Amgen 57
Testing effectiveness (Phase 2)Ended earlyNCT05162066
What this trial is testing

Study to Evaluate the Safety, Tolerability of BCX9930 in Participants With Either Complement 3 Glomerulopathy (C3G), Immunoglobulin A Nephropathy (IgAN), or Primary Membranous Nephropathy (PMN)

Who this might be right for
Complement 3 GlomerulopathyImmunoglobulin A NephropathyMembranous Nephropathy
BioCryst Pharmaceuticals 2
Testing effectiveness (Phase 2)Ended earlyNCT02682407
What this trial is testing

Safety Study of IgAN, LN, MN, & C3 Glomerulopathy Including Dense Deposit Disease Treated With OMS721

Who this might be right for
IgANLNMN+1 more
Omeros Corporation 31
Testing effectiveness (Phase 2)Looking for participantsNCT07522099
What this trial is testing

Chinese Adults With Kidney Disease

Who this might be right for
Immunoglobulin A Nephropathy (IgAN)Complement 3 Glomerulopathy (C3G)IC-MPGN
ADARx Pharmaceuticals, Inc. 30
Large-scale testing (Phase 3)Looking for participantsNCT04817618
What this trial is testing

Study of Efficacy and Safety of Iptacopan in Patients With C3 Glomerulopathy.

Who this might be right for
C3G
Novartis Pharmaceuticals 98
Large-scale testing (Phase 3)Active Not RecruitingNCT05809531
What this trial is testing

An Open-Label, Nonrandomized, Multicenter Extension Study to Evaluate the Long-term Safety and Efficacy of Pegcetacoplan in Participants With C3 Glomerulopathy or Immune-Complex Membranoproliferative Glomerulonephritis

Who this might be right for
C3GIC-MPGNC3 Glomerulopathy+9 more
Apellis Pharmaceuticals, Inc. 100
Not applicableAvailableNCT05222412
What this trial is testing

Managed Access Programs for LNP023, Iptacopan

Who this might be right for
C3 Glomerulopathy (C3G)Paroxysmal Nocturnal Hemoglobinuria (PNH)
Novartis Pharmaceuticals
Not applicableStudy completedNCT01230281
What this trial is testing

Evaluate Pharmacokinetics of C3G and to Estimate Antioxidative Markers After Repeated Administration of Black Bean Seed Coat Extract

Who this might be right for
Oxidative Stress
Seoul St. Mary's Hospital 12
Early research (Phase 1)WithdrawnNCT02302755
What this trial is testing

TP10 Use in Patients With C3 Glomerulopathy (C3G)

Who this might be right for
Dense Deposit Disease
University of Iowa
Testing effectiveness (Phase 2)Study completedNCT03124368
What this trial is testing

A Proof-of-Mechanism Study to Determine the Effect of Danicopan on C3 Levels in Participants With C3G or IC-MPGN

Who this might be right for
C3 GlomerulonephritisDense Deposit DiseaseC3 Glomerulopathy+2 more
Alexion Pharmaceuticals, Inc. 6
Testing effectiveness (Phase 2)Ended earlyNCT03459443
What this trial is testing

A Proof of Concept Study for a 12 Month Treatment in Patients With C3G or IC-MPGN Treated With ACH-0144471

Who this might be right for
C3 GlomerulonephritisC3 GlomerulopathyImmune Complex Membranoproliferative Glomerulonephritis+2 more
Alexion Pharmaceuticals, Inc. 22
Testing effectiveness (Phase 2)Looking for participantsNCT06989359
What this trial is testing

Phase 2 Study of ADX-038 in Complement-Mediated Kidney Disease

Who this might be right for
IgANC3GComplement-mediated Kidney Disease+2 more
ADARx Pharmaceuticals, Inc. 45
Testing effectiveness (Phase 2)Not Yet RecruitingNCT05517980
What this trial is testing

Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of KP104 to Treat Glomerulonephritis

Who this might be right for
Glomerulonephritis
Kira Pharmacenticals (US), LLC. 52
Testing effectiveness (Phase 2)WithdrawnNCT06419205
What this trial is testing

Evaluate the Safety, PD, PK, and Clinical Activity of ADX-097 in Participants With IgAN, LN or C3G

Who this might be right for
IgA NephropathyLupus Nephritis (LN)C3 (Complement Component 3) Glomerulopathy
Q32 Bio Inc.
Early research (Phase 1)Study completedNCT03316521
What this trial is testing

First-In-Human Clinical Study of the C3 Complement Inhibitor AMY- 101 in Healthy Male Volunteers

Who this might be right for
Complement Mediated Diseases
Amyndas Pharmaceuticals S.A. 50
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