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Results for “C3G”

34 trials

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Showing 20 of 34 results

Testing effectiveness (Phase 2)Ended earlyNCT05162066
What this trial is testing

Study to Evaluate the Safety, Tolerability of BCX9930 in Participants With Either Complement 3 Glomerulopathy (C3G), Immunoglobulin A Nephropathy (IgAN), or Primary Membranous Nephropathy (PMN)

Who this might be right for
Complement 3 GlomerulopathyImmunoglobulin A NephropathyMembranous Nephropathy
BioCryst Pharmaceuticals 2
Not applicableNot Yet RecruitingNCT07598448
What this trial is testing

Complement 3 Glomerulopathy (C3G) Patients Treated With Iptacopan Through an Early Access Program in Spain

Who this might be right for
Complement 3 Glomerulopathy
Novartis Pharmaceuticals 35
Large-scale testing (Phase 3)Looking for participantsNCT03955445
What this trial is testing

Long-term Efficacy, Safety and Tolerability of Iptacopan in C3G or IC-MPGN

Who this might be right for
C3 GlomerulopathyImmune-complex-membranoproliferative Glomerulonephritis
Novartis Pharmaceuticals 225
Testing effectiveness (Phase 2)WithdrawnNCT06419205
What this trial is testing

Evaluate the Safety, PD, PK, and Clinical Activity of ADX-097 in Participants With IgAN, LN or C3G

Who this might be right for
IgA NephropathyLupus Nephritis (LN)C3 (Complement Component 3) Glomerulopathy
Q32 Bio Inc.
Large-scale testing (Phase 3)Active Not RecruitingNCT05809531
What this trial is testing

An Open-Label, Nonrandomized, Multicenter Extension Study to Evaluate the Long-term Safety and Efficacy of Pegcetacoplan in Participants With C3 Glomerulopathy or Immune-Complex Membranoproliferative Glomerulonephritis

Who this might be right for
C3GIC-MPGNC3 Glomerulopathy+9 more
Apellis Pharmaceuticals, Inc. 100
Not applicableNot Yet RecruitingNCT07331259
What this trial is testing

CHART-C3G/CLNP023B12011

Who this might be right for
C3 GlomerulopathyComplement-mediated Kidney DiseaseProteinuria
Novartis Pharmaceuticals 83
Early research (Phase 1)Study completedNCT03316521
What this trial is testing

First-In-Human Clinical Study of the C3 Complement Inhibitor AMY- 101 in Healthy Male Volunteers

Who this might be right for
Complement Mediated Diseases
Amyndas Pharmaceuticals S.A. 50
Not applicableLooking for participantsNCT07029542
What this trial is testing

Home Reported Outcomes in C3G Study

Who this might be right for
C3 Glomerulopathy
Novartis Pharmaceuticals 100
Testing effectiveness (Phase 2)Not Yet RecruitingNCT05517980
What this trial is testing

Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of KP104 to Treat Glomerulonephritis

Who this might be right for
Glomerulonephritis
Kira Pharmacenticals (US), LLC. 52
Testing effectiveness (Phase 2)Study completedNCT04572854
What this trial is testing

Study Assessing the Safety and Efficacy of Pegcetacoplan in Post-Transplant Recurrence of C3G or IC-MPGN

Who this might be right for
C3GIC-MPGNRenal Transplant+9 more
Apellis Pharmaceuticals, Inc. 13
Large-scale testing (Phase 3)Looking for participantsNCT05795140
What this trial is testing

Evaluate Long-term Safety, Tolerability and Efficacy of Iptacopan in Study Participants With aHUS

Who this might be right for
Atypical Hemolytic Uremic Syndrome
Novartis Pharmaceuticals 65
Testing effectiveness (Phase 2)Study completedNCT03124368
What this trial is testing

A Proof-of-Mechanism Study to Determine the Effect of Danicopan on C3 Levels in Participants With C3G or IC-MPGN

Who this might be right for
C3 GlomerulonephritisDense Deposit DiseaseC3 Glomerulopathy+2 more
Alexion Pharmaceuticals, Inc. 6
Not applicableStudy completedNCT01230281
What this trial is testing

Evaluate Pharmacokinetics of C3G and to Estimate Antioxidative Markers After Repeated Administration of Black Bean Seed Coat Extract

Who this might be right for
Oxidative Stress
Seoul St. Mary's Hospital 12
Testing effectiveness (Phase 2)Looking for participantsNCT06989359
What this trial is testing

Phase 2 Study of ADX-038 in Complement-Mediated Kidney Disease

Who this might be right for
IgANC3GComplement-mediated Kidney Disease+2 more
ADARx Pharmaceuticals, Inc. 45
Testing effectiveness (Phase 2)Not Yet RecruitingNCT05647811
What this trial is testing

Study of NM8074 in Adult C3 Glomerulopathy Patients

Who this might be right for
C3 Glomerulopathy
NovelMed Therapeutics 18
Not applicableLooking for participantsNCT07345923
What this trial is testing

Predictive Value of a Rectal Swab With Detection of Enterobacteria (ESBL-E), Carbapenemases, and High-level Cephalosporinase (HLC) on the Risk of Infections With C3G-resistant Enterobacteria

Who this might be right for
Infections, Enterobacteriaceae
University Hospital, Strasbourg, France 1,000
Not applicableNot Yet RecruitingNCT07416162
What this trial is testing

Iptacopan in Korean Patients With Paroxysmal Nocturnal Hemoglobinuria or C3 Glomerulopathy

Who this might be right for
Paroxysmal Nocturnal HemoglobinuriaC3 Glomerulopathy
Novartis Pharmaceuticals 21
Not applicableApproved For MarketingNCT04729062
What this trial is testing

C3G/Primary IC-MPGN EAP

Who this might be right for
C3GIC-MPGNC3 Glomerulopathy+9 more
Apellis Pharmaceuticals, Inc.
Not applicableActive Not RecruitingNCT05985122
What this trial is testing

New Analytic Tools for aHUS and C3G Diagnosis

Who this might be right for
Hemolytic-Uremic SyndromeMembranoproliferative GlomerulonephritisHealthy
Mario Negri Institute for Pharmacological Research 180
Testing effectiveness (Phase 2)Looking for participantsNCT07522099
What this trial is testing

Chinese Adults With Kidney Disease

Who this might be right for
Immunoglobulin A Nephropathy (IgAN)Complement 3 Glomerulopathy (C3G)IC-MPGN
ADARx Pharmaceuticals, Inc. 30
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