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Results for “CDKL5”

97 trials

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Showing 20 of 97 results

Early research (Phase 1)Study completedNCT03467113
What this trial is testing

Assess the Safety and Tolerability of ZX008 in Children and Young Adults With Dravet Syndrome or Lennox Gastaut Syndrome Currently Taking Cannabidiol

Who this might be right for
Dravet SyndromeLennox Gastaut Syndrome
Zogenix International Limited, Inc., a subsidiary of Zogenix, Inc. 9
Not applicableLooking for participantsNCT06504511
What this trial is testing

SCN1A Horizons A Natural History Study of SCN1A-related Epilepsies in the United Kingdom

Who this might be right for
SCN1ADravet SyndromeEpilepsy
NHS Greater Glasgow and Clyde 400
Testing effectiveness (Phase 2)Study completedNCT03861871
What this trial is testing

Fenfluramine in CDKL5 Deficiency Disorder (CDD)

Who this might be right for
CDD
NYU Langone Health 7
Not applicableLooking for participantsNCT05485831
What this trial is testing

Epidyolex® in Lennox Gastaut, Dravet Syndrome and Tuberous Sclerosis Complex: an Observational Study in ITALY

Who this might be right for
Lennox Gastaut SyndromeDravet SyndromeTuberous Sclerosis Complex
Jazz Pharmaceuticals 100
Not applicableNot Yet RecruitingNCT07013331
What this trial is testing

A PET-MRI Study of Serotoninergic Brainstem Pathway in Patients With Dravet Syndrome

Who this might be right for
EpilepsyDravet SyndromeDrug Resistant Epilepsy+1 more
Hospices Civils de Lyon 30
Not applicableUnknownNCT04614506
What this trial is testing

Transcranial Magnetic Stimulation to Measure Cortical Excitability in Dravet Syndrome

Who this might be right for
Dravet Syndrome
Boston Children's Hospital 6
Not applicableStudy completedNCT06447675
What this trial is testing

Efficacy and Safety Evaluation of Hyperthermic Baths in the Treatment of Seizures in CDKL5 Deficiency Disorder

Who this might be right for
CDKL5 Deficiency Disorder
Xuanwu Hospital, Beijing 8
Testing effectiveness (Phase 2)Study completedNCT03694275
What this trial is testing

A Multicenter, Open-label, Pilot Study of Soticlestat (TAK-935/OV935) in Participants With 15Q Duplication Syndrome (Dup 15q) or Cyclin-Dependent Kinase-Like 5 (CDKL5) Deficiency Disorder (ARCADE STUDY)

Who this might be right for
15q Duplication SyndromeCDKL5 Deficiency Disease
Takeda 20
Large-scale testing (Phase 3)Study completedNCT03936777
What this trial is testing

Investigate the Long-Term Safety of ZX008 (Fenfluramine Hydrochloride) Oral Solution in Children and Adults With Epileptic Encephalopathy Including Dravet Syndrome and Lennox-Gastaut Syndrome

Who this might be right for
Dravet SyndromeLennox Gastaut SyndromeEpileptic Encephalopathy
Zogenix, Inc. 412
Early research (Phase 1)Study completedNCT04069689
What this trial is testing

Study of Safety and Pharmacokinetics of Oral Doses of EPX-100 in Healthy Subjects.

Who this might be right for
Dravet Syndrome
Epygenix 24
Not applicableStudy completedNCT02896608
What this trial is testing

Neuronal Excitability of HCN1 Channel Mutations in Dravet Syndrome

Who this might be right for
Dravet Syndrome
Fondation Ophtalmologique Adolphe de Rothschild 92
Testing effectiveness (Phase 2)Study completedNCT05626634
What this trial is testing

Open-label, Long-term Safety Study of LP352 in Subjects With Developmental and Epileptic Encephalopathy

Who this might be right for
Developmental and Epileptic EncephalopathyDravet SyndromeLennox-Gastaut Syndrome
Longboard Pharmaceuticals 41
Not applicableStudy completedNCT02415686
What this trial is testing

Cardiac Arrhythmias in Dravet Syndrome

Who this might be right for
Epilepsy
Stichting Epilepsie Instellingen Nederland 59
Not applicableLooking for participantsNCT06448663
What this trial is testing

Targeting the Gut to Improve Seizure Control in CDKL5 Deficiency Disorder (CDD)

Who this might be right for
CDKL5
University of Milan 20
Testing effectiveness (Phase 2)Study completedNCT03650452
What this trial is testing

A Phase 2, Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy, Safety, and Tolerability of TAK-935 (OV935) as an Adjunctive Therapy in Pediatric Participants With Developmental and/or Epileptic Encephalopathies

Who this might be right for
EpilepsyDravet SyndromeLennox-Gastaut Syndrome
Takeda 141
Not applicableLooking for participantsNCT05635266
What this trial is testing

Tissue Repository Providing Annotated Biospecimens for Approved Investigator-directed Biomedical Research Initiatives

Who this might be right for
Age-Related Macular DegenerationAllergiesAlpha-Gal Syndrome+44 more
Sanguine Biosciences 20,000
Testing effectiveness (Phase 2)Study completedNCT01607073
What this trial is testing

Verapamil as Therapy for Children and Young Adults With Dravet Syndrome

Who this might be right for
Dravet Syndrome
Gillette Children's Specialty Healthcare 2
Post-approval studies (Phase 4)Looking for participantsNCT06598449
What this trial is testing

Assessment of Safety of the Use of Fenfluramine in Children With Dravet Syndrome Under 24 Months of Age

Who this might be right for
Dravet Syndrome (DS)Children Under 2 Years
University of Colorado, Denver 12
Large-scale testing (Phase 3)Ended earlyNCT04572243
What this trial is testing

Lorcaserin as Adjunctive Treatment in Participants With Dravet Syndrome

Who this might be right for
Epilepsies, Myoclonic
Eisai Inc. 22
Not applicableLooking for participantsNCT04486768
What this trial is testing

International CDKL5 Registry

Who this might be right for
CDKL5 Deficiency Disorder (CDD)
University of Pennsylvania 500
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