Early research (Phase 1)Study completedNCT05202145What this trial is testingDrug-Drug Interaction (DDI) Study of ALXN2050 in Healthy Adult ParticipantsWho this might be right forHealthy Alexion Pharmaceuticals, Inc. 61
Not applicableStudy completedNCT04926415What this trial is testingEffects of Transcutaneous Auricular Vagus Nerve Stimulation on Obesity and Insulin ResistanceWho this might be right forDiabetes Mellitus, Type 2Obesity Burrell College of Health Sciences 30
Not applicableLooking for participantsNCT07315633What this trial is testingAn Innovative CFD-based Dosimetry and Pre-treatment Planning Platform to Support Personalized Transarterial Therapies for Liver CancerWho this might be right forHepatocellular Carcinoma (HCC)Liver Cancer, AdultLiver Cancer University Hospital, Ghent 80
Testing effectiveness (Phase 2)Ended earlyNCT03459443What this trial is testingA Proof of Concept Study for a 12 Month Treatment in Patients With C3G or IC-MPGN Treated With ACH-0144471Who this might be right forC3 GlomerulonephritisC3 GlomerulopathyImmune Complex Membranoproliferative Glomerulonephritis+2 more Alexion Pharmaceuticals, Inc. 22
Not applicableUnknownNCT06498830What this trial is testingApplication of CTA-based Radiomic Phenotyping of PCAT and Fluid Dynamics in Atherosclerotic Disease (APPLE)Who this might be right forComputed Tomography AngiographyInflammation of Adipose TissueCFD Jinling Hospital, China 2,000
Early research (Phase 1)Study completedNCT04660890What this trial is testingThe Cardiac Effects of ALXN2050 in Healthy AdultsWho this might be right forHealthy Alexion Pharmaceuticals, Inc. 39
Not applicableLooking for participantsNCT06115096What this trial is testingCardiac Hemodynamics During Left Ventricular AssistWho this might be right forHeart Failure Region Östergötland 35
Early research (Phase 1)Study completedNCT04935294What this trial is testingStudy of Danicopan in Participants With Normal Kidney Function and Participants With Kidney DysfunctionWho this might be right forHealthyRenal Dysfunction Alexion Pharmaceuticals, Inc. 16
Large-scale testing (Phase 3)Study completedNCT04469465What this trial is testingDanicopan as Add-on Therapy to a C5 Inhibitor in Paroxysmal Nocturnal Hemoglobinuria (PNH) Participants Who Have Clinically Evident Extravascular Hemolysis (EVH)(ALPHA)Who this might be right forParoxysmal Nocturnal Hemoglobinuria Alexion Pharmaceuticals, Inc. 86
Early research (Phase 1)Study completedNCT03555539What this trial is testingStudy of Danicopan in Participants With Hepatic ImpairmentWho this might be right forHepatic Impairment Alexion Pharmaceuticals, Inc. 16
Early research (Phase 1)Study completedNCT04451434What this trial is testingStudy of Danicopan in Participants of Japanese DescentWho this might be right forHealthy Alexion Pharmaceuticals, Inc. 9
Not applicableStudy completedNCT00966459What this trial is testingComputed Tomography (CT) and Lung Function Data Collection for Computational Fluid Dynamics (CFD) in Chronic Obstructive Pulmonary Disease (COPD) PatientsWho this might be right forChronic Obstructive Pulmonary Disease University Hospital, Antwerp 20
Early research (Phase 1)Study completedNCT05047458What this trial is testingSingle-dose ALXN2050 in Healthy AdultsWho this might be right forHealthy Alexion Pharmaceuticals, Inc. 28
Testing effectiveness (Phase 2)Study completedNCT03369236What this trial is testingA Proof-of-Concept Study of Danicopan for 6 Months of Treatment in Participants With C3 Glomerulopathy (C3G)Who this might be right forC3 GlomerulopathyC3 GlomerulonephritisDense Deposit Disease Alexion Pharmaceuticals, Inc. 13
Not applicableUnknownNCT04428125What this trial is testingCFD Analysis and Risk of TOS in SportWho this might be right forThoracic Outlet SyndromeSport Injury University of Catanzaro 100
Early research (Phase 1)Study completedNCT03384186What this trial is testingModified Release Formulations of Danicopan in Healthy Adult ParticipantsWho this might be right forHealthy Alexion Pharmaceuticals, Inc. 14
Not applicableUnknownNCT06306729What this trial is testingComputational Assessment of Bioprosthetic Aortic Valve FunctionWho this might be right forCFDValve Heart Disease Royal Brompton & Harefield NHS Foundation Trust 20
Early research (Phase 1)Study completedNCT04889690What this trial is testingStudy of Multiple Doses of Danicopan in Healthy ParticipantsWho this might be right forHealthy Alexion Pharmaceuticals, Inc. 45
Testing effectiveness (Phase 2)Ended earlyNCT05116774What this trial is testingBCX9930 for the Treatment of Paroxysmal Nocturnal Hemoglobinuria (PNH) in Participants With Inadequate Response to C5 Inhibitor TherapyWho this might be right forParoxysmal Nocturnal Hemoglobinuria (PNH) BioCryst Pharmaceuticals 12
Not applicableStudy completedNCT07782918What this trial is testingResearch on Aneurysm Growth Prediction in Vascular Dilation Caused by Bicuspid Aortic Valve Based on VDM and CFDWho this might be right forBicuspid Aortic Valve (BAV)Aortic AneurysmTAVR Second Affiliated Hospital, Zhejiang University, School of Medicine 1,000