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Results for “CFD”

52 trials

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Showing 20 of 52 results

Early research (Phase 1)Study completedNCT04551599
What this trial is testing

The Effects of Food and Age on Danicopan

Who this might be right for
Healthy
Alexion Pharmaceuticals, Inc. 27
Not applicableStudy completedNCT04926415
What this trial is testing

Effects of Transcutaneous Auricular Vagus Nerve Stimulation on Obesity and Insulin Resistance

Who this might be right for
Diabetes Mellitus, Type 2Obesity
Burrell College of Osteopathic Medicine 30
Post-approval studies (Phase 4)UnknownNCT01524510
What this trial is testing

Validation of Functional Imaging as Predictive Tool for Outcome of Mandibular Replacement Appliance Therapy in Obstructive Sleep Apnea Hypopnea Syndrome Patients

Who this might be right for
Obstructive Sleep Apnea Syndrome
University Hospital, Antwerp 40
Early research (Phase 1)Study completedNCT03108274
What this trial is testing

A Drug Interaction Study Between Danicopan and Midazolam, Fexofenadine, and Mycophenolate Mofetil in Healthy Participants

Who this might be right for
Healthy
Alexion Pharmaceuticals, Inc. 35
Early research (Phase 1)Study completedNCT04609696
What this trial is testing

Study of the Metabolism of Danicopan in Healthy Adults

Who this might be right for
Healthy
Alexion Pharmaceuticals, Inc. 24
Early research (Phase 1)Study completedNCT04623710
What this trial is testing

Study of ALXN2050 in Participants With Renal Impairment

Who this might be right for
Renal ImpairmentHealthy
Alexion Pharmaceuticals, Inc. 40
Not applicableLooking for participantsNCT07002697
What this trial is testing

Geometrical Influences on Atherosclerosis and Blood Flow

Who this might be right for
Atherosclerosis and Blood Flow in Coronary Artery
Bangladesh University of Engineering and Technology 30
Not applicableUnknownNCT06498830
What this trial is testing

Application of CTA-based Radiomic Phenotyping of PCAT and Fluid Dynamics in Atherosclerotic Disease (APPLE)

Who this might be right for
Computed Tomography AngiographyInflammation of Adipose TissueCFD
Jinling Hospital, China 2,000
Early research (Phase 1)Study completedNCT04551586
What this trial is testing

Assess ACH-0145228 When Administered as Immediate Release Tablet Versus Powder-In-Capsule in Healthy Adult Participants

Who this might be right for
Healthy
Alexion Pharmaceuticals, Inc. 28
Not applicableStudy completedNCT04141852
What this trial is testing

VasQ and Hemodynamic Conditions in AVFs

Who this might be right for
Renal Insufficiency, Chronic
Mario Negri Institute for Pharmacological Research 6
Early research (Phase 1)Study completedNCT04889690
What this trial is testing

Study of Multiple Doses of Danicopan in Healthy Participants

Who this might be right for
Healthy
Alexion Pharmaceuticals, Inc. 45
Early research (Phase 1)Study completedNCT04709094
What this trial is testing

A Drug Interaction Study of Danicopan

Who this might be right for
Healthy
Alexion Pharmaceuticals, Inc. 52
Testing effectiveness (Phase 2)Ended earlyNCT04170023
What this trial is testing

Study of the Oral Factor D (FD) Inhibitor ALXN2050 in PNH Patients as Monotherapy

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria (PNH)
Alexion Pharmaceuticals, Inc. 29
Large-scale testing (Phase 3)Active Not RecruitingNCT05389449
What this trial is testing

A Long-term Safety and Efficacy Study of Danicopan as an Add-on Therapy to Complement Component 5 Inhibitor (C5i) in Participants With PNH

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
Alexion Pharmaceuticals, Inc. 80
Testing effectiveness (Phase 2)Ended earlyNCT05097989
What this trial is testing

Study of ALXN2050 in Proliferative Lupus Nephritis (LN) or Immunoglobulin A Nephropathy (IgAN)

Who this might be right for
Lupus NephritisImmunoglobulin A NephropathyIgAN+1 more
Alexion Pharmaceuticals, Inc. 100
Early research (Phase 1)Study completedNCT04940559
What this trial is testing

Study of Different Forms of Danicopan (Tablet, Softgel Capsule, Liquid-filled Capsule) in Healthy Participants

Who this might be right for
Healthy
Alexion Pharmaceuticals, Inc. 26
Testing effectiveness (Phase 2)Ended earlyNCT05116787
What this trial is testing

BCX9930 for the Treatment of Paroxysmal Nocturnal Hemoglobinuria (PNH) in Participants Not Receiving Other Complement Inhibitor Therapy

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria (PNH)
BioCryst Pharmaceuticals 12
Testing effectiveness (Phase 2)Study completedNCT03124368
What this trial is testing

A Proof-of-Mechanism Study to Determine the Effect of Danicopan on C3 Levels in Participants With C3G or IC-MPGN

Who this might be right for
C3 GlomerulonephritisDense Deposit DiseaseC3 Glomerulopathy+2 more
Alexion Pharmaceuticals, Inc. 6
Early research (Phase 1)Study completedNCT03384186
What this trial is testing

Modified Release Formulations of Danicopan in Healthy Adult Participants

Who this might be right for
Healthy
Alexion Pharmaceuticals, Inc. 14
Early research (Phase 1)Study completedNCT04935294
What this trial is testing

Study of Danicopan in Participants With Normal Kidney Function and Participants With Kidney Dysfunction

Who this might be right for
HealthyRenal Dysfunction
Alexion Pharmaceuticals, Inc. 16
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