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Results for “CFD”

52 trials

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Showing 20 of 52 results

Early research (Phase 1)Study completedNCT04551586
What this trial is testing

Assess ACH-0145228 When Administered as Immediate Release Tablet Versus Powder-In-Capsule in Healthy Adult Participants

Who this might be right for
Healthy
Alexion Pharmaceuticals, Inc. 28
Testing effectiveness (Phase 2)Ended earlyNCT05162066
What this trial is testing

Study to Evaluate the Safety, Tolerability of BCX9930 in Participants With Either Complement 3 Glomerulopathy (C3G), Immunoglobulin A Nephropathy (IgAN), or Primary Membranous Nephropathy (PMN)

Who this might be right for
Complement 3 GlomerulopathyImmunoglobulin A NephropathyMembranous Nephropathy
BioCryst Pharmaceuticals 2
Not applicableStudy completedNCT06495151
What this trial is testing

Endometriosis and Complement System

Who this might be right for
EndometriosisComplement SystemAlternative Complement Pathway
Ankara City Hospital Bilkent 58
Testing effectiveness (Phase 2)Study completedNCT04330534
What this trial is testing

First-in-Human Study of BCX9930 in Healthy Volunteers and Patients With PNH

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
BioCryst Pharmaceuticals 168
Early research (Phase 1)Study completedNCT04889690
What this trial is testing

Study of Multiple Doses of Danicopan in Healthy Participants

Who this might be right for
Healthy
Alexion Pharmaceuticals, Inc. 45
Early research (Phase 1)Study completedNCT05047458
What this trial is testing

Single-dose ALXN2050 in Healthy Adults

Who this might be right for
Healthy
Alexion Pharmaceuticals, Inc. 28
Early research (Phase 1)Study completedNCT04451434
What this trial is testing

Study of Danicopan in Participants of Japanese Descent

Who this might be right for
Healthy
Alexion Pharmaceuticals, Inc. 9
Not applicableLooking for participantsNCT07002697
What this trial is testing

Geometrical Influences on Atherosclerosis and Blood Flow

Who this might be right for
Atherosclerosis and Blood Flow in Coronary Artery
Bangladesh University of Engineering and Technology 30
Early research (Phase 1)Study completedNCT03555539
What this trial is testing

Study of Danicopan in Participants With Hepatic Impairment

Who this might be right for
Hepatic Impairment
Alexion Pharmaceuticals, Inc. 16
Not applicableStudy completedNCT01684384
What this trial is testing

Research to Evaluate a Possible Relation Between Values Obtained After Processing CT Images, Lung Function Tests and the Experience of the Patient During an Exacerbation in COPD Patients.

Who this might be right for
Pulmonary Disease, Chronic Obstructive
FLUIDDA nv 53
Testing effectiveness (Phase 2)Ended earlyNCT04702568
What this trial is testing

A Long-Term Safety Study of BCX9930 in Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH)

Who this might be right for
Paroxysmal Nocturnal HemoglobinuriaPNH
BioCryst Pharmaceuticals 19
Not applicableStudy completedNCT04141852
What this trial is testing

VasQ and Hemodynamic Conditions in AVFs

Who this might be right for
Renal Insufficiency, Chronic
Mario Negri Institute for Pharmacological Research 6
Early research (Phase 1)Study completedNCT03108274
What this trial is testing

A Drug Interaction Study Between Danicopan and Midazolam, Fexofenadine, and Mycophenolate Mofetil in Healthy Participants

Who this might be right for
Healthy
Alexion Pharmaceuticals, Inc. 35
Not applicableStudy completedNCT00966459
What this trial is testing

Computed Tomography (CT) and Lung Function Data Collection for Computational Fluid Dynamics (CFD) in Chronic Obstructive Pulmonary Disease (COPD) Patients

Who this might be right for
Chronic Obstructive Pulmonary Disease
University Hospital, Antwerp 20
Testing effectiveness (Phase 2)Study completedNCT03124368
What this trial is testing

A Proof-of-Mechanism Study to Determine the Effect of Danicopan on C3 Levels in Participants With C3G or IC-MPGN

Who this might be right for
C3 GlomerulonephritisDense Deposit DiseaseC3 Glomerulopathy+2 more
Alexion Pharmaceuticals, Inc. 6
Not applicableStudy completedNCT04926415
What this trial is testing

Effects of Transcutaneous Auricular Vagus Nerve Stimulation on Obesity and Insulin Resistance

Who this might be right for
Diabetes Mellitus, Type 2Obesity
Burrell College of Osteopathic Medicine 30
Testing effectiveness (Phase 2)Ended earlyNCT05116774
What this trial is testing

BCX9930 for the Treatment of Paroxysmal Nocturnal Hemoglobinuria (PNH) in Participants With Inadequate Response to C5 Inhibitor Therapy

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria (PNH)
BioCryst Pharmaceuticals 12
Early research (Phase 1)Study completedNCT04940559
What this trial is testing

Study of Different Forms of Danicopan (Tablet, Softgel Capsule, Liquid-filled Capsule) in Healthy Participants

Who this might be right for
Healthy
Alexion Pharmaceuticals, Inc. 26
Early research (Phase 1)Study completedNCT03384186
What this trial is testing

Modified Release Formulations of Danicopan in Healthy Adult Participants

Who this might be right for
Healthy
Alexion Pharmaceuticals, Inc. 14
Early research (Phase 1)Study completedNCT05047484
What this trial is testing

Multiple Doses of ALXN2050 in Healthy Adults

Who this might be right for
Healthy
Alexion Pharmaceuticals, Inc. 45
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