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Results for “CLN11 Disease”

13 trials

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Showing 13 of 13 results

Early research (Phase 1)Looking for participantsNCT05627960
What this trial is testing

First in Human Phase 1 Study of AG01 Anti-Progranulin/GP88 Antibody in Advanced Solid Tumor Malignancies

Who this might be right for
Triple Negative Breast CancerHormone-Resistant Breast CancerNon Small Cell Lung Cancer+1 more
A&G Pharmaceutical Inc. 77
Large-scale testing (Phase 3)Ended earlyNCT04374136
What this trial is testing

Evaluate Efficacy and Safety of AL001 in Frontotemporal Dementia (INFRONT-3)

Who this might be right for
Frontotemporal Dementia
Alector Inc. 119
Not applicableStudy completedNCT01869816
What this trial is testing

CTRP3 and Progranulin in Patients With Coronary Artery Disease

Who this might be right for
Coronary Artery Disease
Korea University 362
Testing effectiveness (Phase 2)Active Not RecruitingNCT04747431
What this trial is testing

PBFT02 in Participants With FTD and Mutations in the Granulin Precursor (GRN) or C9ORF72 Genes

Who this might be right for
Frontotemporal DementiaFTDFTD-GRN+2 more
Passage Bio, Inc. 30
Not applicableEnded earlyNCT02700776
What this trial is testing

1380GCC: Prospective Study of GP-88 Blood Test in Healthy Women With Baseline Gail Model Risk Assessment Undergoing Screening for Breast Cancer

Who this might be right for
Healthy Volunteers
University of Maryland, Baltimore 417
Not applicableStudy completedNCT04060082
What this trial is testing

Voices Of Individuals: Challenges and Experiences Of bvFTD

Who this might be right for
Frontotemporal DementiaFrontotemporal DegenerationFrontotemporal Dementia, Behavioral Variant+1 more
University of Pennsylvania 26
Testing effectiveness (Phase 2)Looking for participantsNCT06064890
What this trial is testing

Evaluate the Safety and Effect of AVB-101, a Gene Therapy Product, in Subjects With a Genetic Sub-type of Frontotemporal Dementia (FTD-GRN)

Who this might be right for
Frontotemporal DementiaFTDFTD-GRN+1 more
AviadoBio Ltd 18
Not applicableLooking for participantsNCT04613089
What this trial is testing

Natural History and Longitudinal Clinical Assessments in NCL / Batten Disease, the International DEM-CHILD Database

Who this might be right for
Neuronal Ceroid LipofuscinosisBatten DiseaseCLN1 Disease+12 more
Universitätsklinikum Hamburg-Eppendorf 500
Not applicableUnknownNCT04451616
What this trial is testing

Assessment of Progranulin and FAM19A5 Protein Blood Levels in Metabolic Syndrome

Who this might be right for
Nutrition DisordersHypertensionDyslipidemias+5 more
Poznan University of Medical Sciences 80
Testing effectiveness (Phase 2)Active Not RecruitingNCT04408625
What this trial is testing

Phase 1/2 Clinical Trial of LY3884963 in Patients With Frontotemporal Dementia With Progranulin Mutations (FTD-GRN)

Who this might be right for
Frontotemporal Dementia
Prevail Therapeutics 35
Not applicableStudy completedNCT01668888
What this trial is testing

Progranulin and CTRP3 in Metabolic Syndrome

Who this might be right for
Metabolic Syndrome
Korea University 127
Not applicableStudy completedNCT02999282
What this trial is testing

Rehabilitative Trial for the Rescue of Neurophysiological Parameters in Progranulin Deficient Subjects

Who this might be right for
Frontotemporal DementiaGRN Related Frontotemporal Dementia
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia 70
Not applicableActive Not RecruitingNCT07117344
What this trial is testing

Biomarkers in Ankylosing Spondylitis

Who this might be right for
Ankylosing Spondylitis (AS) / Radiographic Axial SpA (r-axSpA)
Kirsehir Ahi Evran Universitesi 160