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Results for “CTLA4”

332 trials

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Showing 20 of 332 results

Large-scale testing (Phase 3)Active Not RecruitingNCT07000149
What this trial is testing

Investigate the Efficacy and Safety of Volrustomig ± Casdatifan vs Nivolumab + Ipilimumab as 1L Treatment for Advanced ccRCC

Who this might be right for
Advanced Clear Cell Renal Cell Carcinoma
AstraZeneca 1,116
Post-approval studies (Phase 4)Not Yet RecruitingNCT07004335
What this trial is testing

Efficacy and Safety of Iparomlimab and Tuvonralimab Injection in Combination With Bevacizumab After Progression on Anti-PD-(L)1 Therapy in Advanced Melanoma: A Prospective, Single-Arm, Exploratory Clinical Study

Who this might be right for
PD-(L)1CTLA-4Advanced Melanoma+3 more
Hebei Medical University Fourth Hospital 40
Testing effectiveness (Phase 2)Study completedNCT04444167
What this trial is testing

Anti-PD-1/CTLA-4 Bispecific AK104 Plus Lenvatinib in First-line Advanced Hepatocellular Carcinoma

Who this might be right for
Hepatocellular Carcinoma
Akeso 59
Not applicableNot Yet RecruitingNCT06155422
What this trial is testing

A Prospective Real-world Study of Cadonilimab in Patients With Recurrent or Metastatic Cervical Cancer

Who this might be right for
Recurrent or Metastatic Cervical Cancer
Gang Chen (101199) 670
Early research (Phase 1)Ended earlyNCT03674502
What this trial is testing

Safety of ADU-1604 in Adults With Metastatic Melanoma

Who this might be right for
Metastatic Melanoma
Aduro Biotech, Inc. 4
Testing effectiveness (Phase 2)Study completedNCT02027935
What this trial is testing

CD8+ Antigen-Specific T Cells, Cyclophosphamide, Aldesleukin, and Ipilimumab in Treating Patients With Metastatic Melanoma

Who this might be right for
Metastatic MelanomaStage IV Cutaneous Melanoma AJCC v6 and v7
M.D. Anderson Cancer Center 16
Large-scale testing (Phase 3)Looking for participantsNCT06618664
What this trial is testing

Study of SHR-8068 Combined With Adebrelimab and Bevacizumab Versus Sintilimab Combined With Bevacizumab for the Treatment of Advanced Hepatocellular Carcinoma

Who this might be right for
Advanced Hepatocellular Carcinoma
Suzhou Suncadia Biopharmaceuticals Co., Ltd. 590
Not applicableLooking for participantsNCT06627595
What this trial is testing

Impact of Physical Activity on Immunotherapy-induced Toxicities in Melanoma Management

Who this might be right for
MelanomaImmunotoxicity
University Hospital, Montpellier 160
Large-scale testing (Phase 3)Looking for participantsNCT06794775
What this trial is testing

SWE-NEO: Swedish NeoAdjuvant Trial Comparing Monotherapy to Combined Immunotherapy in Resectable Stage III Melanoma

Who this might be right for
Malignant Melanoma Stage III
Hildur Helgadottir 128
Early research (Phase 1)Active Not RecruitingNCT05858736
What this trial is testing

Safety, PK and Efficacy of AI-061 in Advanced Solid Tumors

Who this might be right for
MelanomaNon Small Cell Lung CancerHead and Neck Squamous Cell Carcinoma+14 more
OncoC4, Inc. 18
Testing effectiveness (Phase 2)WithdrawnNCT01530984
What this trial is testing

Ipilimumab and GMCSF Immunotherapy for Prostate Cancer

Who this might be right for
Prostate Cancer
Lawrence Fong
Testing effectiveness (Phase 2)Active Not RecruitingNCT04305054
What this trial is testing

Substudy 02B: Safety and Efficacy of Pembrolizumab in Combination With Investigational Agents or Pembrolizumab Alone in Participants With First Line (1L) Advanced Melanoma (MK-3475-02B/KEYMAKER-U02)

Who this might be right for
Melanoma
Merck Sharp & Dohme LLC 315
Early research (Phase 1)Study completedNCT04121676
What this trial is testing

Anti-CD137 and Anti-CTLA-4 Monoclonal Antibody in Patients With Advanced Cancer

Who this might be right for
Advanced Cancer
Agenus Inc. 91
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07243951
What this trial is testing

Phase II Clinical Study on the Efficacy and Safety of the Combination of Cadonilimab and Capecitabine in Adjuvant Therapy for Combined Hepatocellular Carcinoma and Intrahepatic Cholangiocarcinoma

Who this might be right for
Combined Hepatocellular-cholangiocarcinomaLiver Neoplasms
Shanghai Zhongshan Hospital 75
Early research (Phase 1)Study completedNCT05559554
What this trial is testing

Evaluate the PK Similarity of AK104 in Healthy Chinese Male Subjects

Who this might be right for
Healthy Male Subjects
Akeso 100
Testing effectiveness (Phase 2)Active Not RecruitingNCT04140526
What this trial is testing

Safety, PK and Efficacy of ONC-392 in Monotherapy and in Combination of Anti-PD-1 in Advanced Solid Tumors and NSCLC

Who this might be right for
Non Small Cell Lung CancerAdvanced Solid TumorMetastatic Melanoma+16 more
OncoC4, Inc. 733
Testing effectiveness (Phase 2)Ended earlyNCT06834399
What this trial is testing

TATE and KN046 in MCRC

Who this might be right for
Colorectal Cancer with Hepatic Metastases
Zhejiang Raygene Pharmaceuticals Co., Ltd 42
Early research (Phase 1)WithdrawnNCT02868632
What this trial is testing

Study of Immune Checkpoint Inhibition With Radiation Therapy in Unresectable, Non-metastatic Pancreatic Cancer

Who this might be right for
Pancreatic Cancer
NYU Langone Health
Early research (Phase 1)Ended earlyNCT01940809
What this trial is testing

Ipilimumab With or Without Dabrafenib, Trametinib, and/or Nivolumab in Treating Patients With Melanoma That Is Metastatic or Cannot Be Removed by Surgery

Who this might be right for
BRAF V600E Mutation PresentBRAF V600K Mutation PresentMetastatic Melanoma+5 more
National Cancer Institute (NCI) 15
Early research (Phase 1)Study completedNCT00047164
What this trial is testing

Monoclonal Antibody Therapy in Treating Patients With Lymphoma or Colon Cancer That Has Not Responded to Vaccine Therapy

Who this might be right for
Lymphoma
National Institutes of Health Clinical Center (CC) 89
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