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Results for “CTLA4”

338 trials

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Showing 20 of 338 results

Post-approval studies (Phase 4)Not Yet RecruitingNCT07004335
What this trial is testing

Efficacy and Safety of Iparomlimab and Tuvonralimab Injection in Combination With Bevacizumab After Progression on Anti-PD-(L)1 Therapy in Advanced Melanoma: A Prospective, Single-Arm, Exploratory Clinical Study

Who this might be right for
PD-(L)1CTLA-4Advanced Melanoma+3 more
Hebei Medical University Fourth Hospital 40
Very early researchStudy completedNCT04301414
What this trial is testing

Non-fucosylated Anti-CTLA-4 (BMS-986218) + Degarelix Acetate vs. Degarelix Acetate Alone in Men With High-risk Localized Prostate Cancer

Who this might be right for
Prostate Cancer
Columbia University 26
Not applicableNot Yet RecruitingNCT07014904
What this trial is testing

"Cytotoxic T Lymphocyte-Associated Antigen-4 (CTLA-4) Gene Single-nucleotide Polymorphism in Primary Immune Thrombocytopenic Purpura in Children"

Who this might be right for
ITP - Immune Thrombocytopenia
Sohag University 80
Testing effectiveness (Phase 2)Study completedNCT01714739
What this trial is testing

An Anti-KIR Antibody Lirilumab in Combination With an Anti-PD1 Antibody Nivolumab and Nivolumab Plus an Anti-CTLA-4 Ipilimumab Antibody in Patients With Advanced Solid Tumors

Who this might be right for
CANCER,NOS
Bristol-Myers Squibb 337
Early research (Phase 1)Study completedNCT01750983
What this trial is testing

Ipilimumab and Lenalidomide in Advanced Cancer

Who this might be right for
Advanced Cancers
M.D. Anderson Cancer Center 101
Early research (Phase 1)Study completedNCT00060372
What this trial is testing

Ipilimumab After Allogeneic Stem Cell Transplant in Treating Patients With Persistent or Progressive Cancer

Who this might be right for
Adult Acute Myeloid Leukemia With 11q23 (MLL) AbnormalitiesAdult Acute Myeloid Leukemia With Inv(16)(p13;q22)Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)+59 more
National Cancer Institute (NCI) 21
Early research (Phase 1)Study completedNCT05118334
What this trial is testing

IBI310 (Anti-CTLA-4) in Combination With Sintilimab in Patients With Non-small-cell Lung Cancer (NSCLC)

Who this might be right for
NSCLC (Non-small-cell Lung Cancer)
Innovent Biologics (Suzhou) Co. Ltd. 30
Large-scale testing (Phase 3)Active Not RecruitingNCT07000149
What this trial is testing

Investigate the Efficacy and Safety of Volrustomig ± Casdatifan vs Nivolumab + Ipilimumab as 1L Treatment for Advanced ccRCC

Who this might be right for
Advanced Clear Cell Renal Cell Carcinoma
AstraZeneca 1,116
Early research (Phase 1)Study completedNCT04572152
What this trial is testing

AK119 (Anti-CD73) in Combination With AK104 in Subjects With Advanced Solid Tumors

Who this might be right for
Advanced or Metastatic Solid Tumors
Akeso 23
Testing effectiveness (Phase 2)Active Not RecruitingNCT04140526
What this trial is testing

Safety, PK and Efficacy of ONC-392 in Monotherapy and in Combination of Anti-PD-1 in Advanced Solid Tumors and NSCLC

Who this might be right for
Non Small Cell Lung CancerAdvanced Solid TumorMetastatic Melanoma+16 more
OncoC4, Inc. 733
Large-scale testing (Phase 3)Active Not RecruitingNCT05587374
What this trial is testing

Cadonilimab (PD-1/CTLA-4 Bispecific Blockade) and Chemoradiotherapy in Nasopharyngeal Carcinoma (GEMSTONE)

Who this might be right for
Nasopharyngeal CarcinomaNasopharyngeal Cancer
Sun Yat-sen University 490
Testing effectiveness (Phase 2)Study completedNCT01853618
What this trial is testing

Tremelimumab With Chemoembolization or Ablation for Liver Cancer

Who this might be right for
Heptocellular CancerBiliary Tract NeoplasmsLiver Cancer+2 more
National Cancer Institute (NCI) 61
Early research (Phase 1)Ended earlyNCT02070406
What this trial is testing

Gene-Modified T Cells, Vaccine Therapy, and Ipilimumab in Treating Patients With Locally Advanced or Metastatic Malignancies

Who this might be right for
Unspecified Adult Solid Tumor, Protocol Specific
Jonsson Comprehensive Cancer Center 4
Early research (Phase 1)Ended earlyNCT01940809
What this trial is testing

Ipilimumab With or Without Dabrafenib, Trametinib, and/or Nivolumab in Treating Patients With Melanoma That Is Metastatic or Cannot Be Removed by Surgery

Who this might be right for
BRAF V600E Mutation PresentBRAF V600K Mutation PresentMetastatic Melanoma+5 more
National Cancer Institute (NCI) 15
Testing effectiveness (Phase 2)UnknownNCT04324307
What this trial is testing

Study of Immunotherapy Combined With Chemotherapy in Locally Advanced and Metastatic Pancreatic Cancer

Who this might be right for
Locally Advanced and Metastatic Pancreatic Cancer
Changhai Hospital 60
Early research (Phase 1)Ended earlyNCT05695898
What this trial is testing

XmAb23104 (PD1 X ICOS) and XmAb22841 (CTLA-4 X LAG3) in Treating Melanoma Prior Immune Checkpoint Inhibitor Therapy

Who this might be right for
Metastatic MelanomaAdvanced Melanoma
University of California, San Francisco 6
Testing effectiveness (Phase 2)Active Not RecruitingNCT05014776
What this trial is testing

Study of CRS-207, Pembrolizumab, Ipilimumab, and Tadalafil in Metastatic Pancreatic Cancer

Who this might be right for
Pancreatic Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 17
Early research (Phase 1)Ended earlyNCT01216436
What this trial is testing

Local Modulation of Immune Receptors to Enhance the Response to Dendritic Cell Vaccination in Metastatic Melanoma

Who this might be right for
Metastatic Melanoma
Duke University 2
Testing effectiveness (Phase 2)Looking for participantsNCT07230613
What this trial is testing

Neo-adjuvant Immunotherapy in Patients With Localized Melanoma

Who this might be right for
Cutaneous Melanoma, Stage IIIMucosal Melanoma
UNICANCER 50
Large-scale testing (Phase 3)Active Not RecruitingNCT01274338
What this trial is testing

Ipilimumab or High-Dose Interferon Alfa-2b in Treating Patients With High-Risk Stage III-IV Melanoma That Has Been Removed by Surgery

Who this might be right for
Melanoma of Unknown PrimaryRecurrent MelanomaStage IIIB Cutaneous Melanoma AJCC v7+2 more
National Cancer Institute (NCI) 1,673
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