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Results for “CTLA4”

344 trials

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Showing 20 of 344 results

Testing effectiveness (Phase 2)Not Yet RecruitingNCT07397442
What this trial is testing

Short-Course Radiotherapy Combined With Chemotherapy and Immunotherapy in Mid-Low Locally Advanced Rectal Cancer

Who this might be right for
Rectal Cancer, AdenocarcinomaRectal Cancer Stage IIRectal Cancer Stage III
Beijing Friendship Hospital 19
Large-scale testing (Phase 3)Study completedNCT02551159
What this trial is testing

Phase III Open Label Study of MEDI 4736 With/Without Tremelimumab Versus Standard of Care (SOC) in Recurrent/Metastatic Head and Neck Cancer

Who this might be right for
Squamous Cell Carcinoma of the Head and Neck
AstraZeneca 823
Testing effectiveness (Phase 2)Ended earlyNCT03993379
What this trial is testing

PROCLAIM: CX-072-002: Study of PD-L1 Probody Therapeutic CX-072 in Combination With Other Anticancer Therapy in Adults With Solid Tumors

Who this might be right for
Solid TumorUnresectable or Metastatic Melanoma
CytomX Therapeutics 3
Testing effectiveness (Phase 2)Study completedNCT00170157
What this trial is testing

Hormone Therapy and Ipilimumab in Treating Patients With Advanced Prostate Cancer

Who this might be right for
Prostate AdenocarcinomaProstate CarcinomaRecurrent Prostate Carcinoma+2 more
Mayo Clinic 112
Early research (Phase 1)Study completedNCT03507699
What this trial is testing

Combined Immunotherapy and Radiosurgery for Metastatic Colorectal Cancer

Who this might be right for
Colorectal Neoplasms MalignantLiver Metastases
Sheba Medical Center 19
Testing effectiveness (Phase 2)Looking for participantsNCT07410975
What this trial is testing

Efficacy of Anti-CTLA-4 Antibody Combined With Sintilimab and Chemotherapy as Neoadjuvant Therapy for Resectable Stage II-III Non-Small Cell Lung Cancer

Who this might be right for
NSCLC Stage IINSCLC Stage III
Shanghai Pulmonary Hospital, Shanghai, China 54
Early research (Phase 1)Temporarily pausedNCT04840589
What this trial is testing

Testing the Combination of ZEN003694 and Nivolumab With or Without Ipilimumab in Solid Tumors

Who this might be right for
Metastatic Malignant Solid NeoplasmRecurrent Malignant Solid NeoplasmRecurrent Platinum-Resistant Ovarian Carcinoma+1 more
National Cancer Institute (NCI) 66
Testing effectiveness (Phase 2)Study completedNCT04868708
What this trial is testing

AK104（ an Anti-PD-1 and Anti-CTLA-4 Bispecific Antibody) in Recurrent or Metastatic Cervical Cancer

Who this might be right for
Recurrent or Metastatic Cervical Cancer
Akeso 50
Testing effectiveness (Phase 2)Study completedNCT02027935
What this trial is testing

CD8+ Antigen-Specific T Cells, Cyclophosphamide, Aldesleukin, and Ipilimumab in Treating Patients With Metastatic Melanoma

Who this might be right for
Metastatic MelanomaStage IV Cutaneous Melanoma AJCC v6 and v7
M.D. Anderson Cancer Center 16
Testing effectiveness (Phase 2)Active Not RecruitingNCT02962063
What this trial is testing

Durvalumab, an Anti-PDLI Antibody, and Tremelimumab, an Anti-CTLA4 Antibody, and Chemoradiation Before Surgery for Esophageal Cancer

Who this might be right for
Esophageal AdenocarcinomaGastroesophageal Junction Adenocarcinoma
Memorial Sloan Kettering Cancer Center 64
Early research (Phase 1)UnknownNCT03527251
What this trial is testing

Anti-CTLA-4 Antibody Followed by Anti-PD-1 Antibody in Recurrent or Metastatic NSCLC

Who this might be right for
Non Small Cell Lung Cancer
Sun Yat-sen University 10
Not applicableLooking for participantsNCT07354971
What this trial is testing

IMMUNO-FIT Observational Study

Who this might be right for
NeoplasmsImmunotherapyPhysical Fitness+2 more
University Hospital Southampton NHS Foundation Trust 67
Testing effectiveness (Phase 2)Study completedNCT02254772
What this trial is testing

A Phase I/II Study of Intratumoral Injection of SD-101

Who this might be right for
Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid TissueNodal Marginal Zone B-cell LymphomaRecurrent Grade 1 Follicular Lymphoma+4 more
Robert Lowsky 9
Testing effectiveness (Phase 2)Looking for participantsNCT06367075
What this trial is testing

A Trial of Cadonilimab With Adriamycin in Patients With Advanced Soft Tissue Sarcoma

Who this might be right for
Advanced Soft-tissue Sarcoma
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 53
Testing effectiveness (Phase 2)Looking for participantsNCT06769971
What this trial is testing

Phase II Study of Ivonescimab and Cadonilimab in Combination with Chemotherapy in Patients with ES-SCLC

Who this might be right for
Small Cell Lung Cancer
Sichuan University 80
Testing effectiveness (Phase 2)Ended earlyNCT06834399
What this trial is testing

TATE and KN046 in MCRC

Who this might be right for
Colorectal Cancer with Hepatic Metastases
Zhejiang Raygene Pharmaceuticals Co., Ltd 42
Testing effectiveness (Phase 2)Active Not RecruitingNCT02834013
What this trial is testing

Nivolumab and Ipilimumab in Treating Patients With Rare Tumors

Who this might be right for
Acinar Cell CarcinomaAdenoid Cystic CarcinomaAdrenal Cortical Carcinoma+91 more
National Cancer Institute (NCI) 798
Not applicableLooking for participantsNCT02257892
What this trial is testing

Novel Genetic Disorders of the Immune System

Who this might be right for
PI3KCDCTLA4STAT3GOF+1 more
National Institute of Allergy and Infectious Diseases (NIAID) 500
Early research (Phase 1)Looking for participantsNCT03198052
What this trial is testing

GPC3/Mesothelin/Claudin18.2/GUCY2C/B7-H3/PSCA/PSMA/MUC1/TGFβ/HER2/Lewis-Y/AXL/EGFR-CAR-T Cells Against Cancers

Who this might be right for
Lung CancerCancerImmunotherapy+1 more
Second Affiliated Hospital of Guangzhou Medical University 30
Early research (Phase 1)Not Yet RecruitingNCT07476326
What this trial is testing

Pharmacokinetics, Safety, and Immunogenicity Comparison of Bmab1700 and Opdivo® as Adjuvant Monotherapy in Participants With Melanoma

Who this might be right for
Melanoma
Biocon Biologics UK PLC 120
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