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Results for “CTLA4”

353 trials

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Showing 20 of 353 results

Testing effectiveness (Phase 2)UnknownNCT06406673
What this trial is testing

A Phase II Clinical Study of Cadonilimab in Treatment-naïve or Relapsed Extensive Small Cell Lung Cancer

Who this might be right for
Extensive Small Cell Lung Cancer
Henan Cancer Hospital 70
Early research (Phase 1)Ended earlyNCT03580694
What this trial is testing

Study of REGN4659 in Combination With Cemiplimab in Patients With Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)

Who this might be right for
Carcinoma, Non-Small-Cell Lung
Regeneron Pharmaceuticals 17
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07243951
What this trial is testing

Phase II Clinical Study on the Efficacy and Safety of the Combination of Cadonilimab and Capecitabine in Adjuvant Therapy for Combined Hepatocellular Carcinoma and Intrahepatic Cholangiocarcinoma

Who this might be right for
Combined Hepatocellular-cholangiocarcinomaLiver Neoplasms
Shanghai Zhongshan Hospital 75
Large-scale testing (Phase 3)Ended earlyNCT03515629
What this trial is testing

REGN2810 (Anti-PD-1 Antibody), Platinum-based Doublet Chemotherapy, and Ipilimumab (Anti-CTLA-4 Antibody) Versus Pembrolizumab Monotherapy in Patients With Lung Cancer

Who this might be right for
Non-small Cell Lung Cancer
Regeneron Pharmaceuticals 5
Testing effectiveness (Phase 2)UnknownNCT06509971
What this trial is testing

QL1706 (an Anti-PD-1/CTLA-4 Combined Antibody) Combined With Albumin-bound Paclitaxel and Bevacizumab in the Treatment of Platinum-resistant Recurrent Ovarian Cancer

Who this might be right for
Platinum-resistant Recurrent Ovarian Cancer
West China Second University Hospital 39
Early research (Phase 1)Ended earlyNCT01216436
What this trial is testing

Local Modulation of Immune Receptors to Enhance the Response to Dendritic Cell Vaccination in Metastatic Melanoma

Who this might be right for
Metastatic Melanoma
Duke University 2
Testing effectiveness (Phase 2)Study completedNCT02821754
What this trial is testing

A Pilot Study of Combined Immune Checkpoint Inhibition in Combination With Ablative Therapies in Subjects With Hepatocellular Carcinoma (HCC) or Biliary Tract Carcinomas (BTC)

Who this might be right for
Biliary Tract NeoplasmsLiver CancerHepatocellular Carcinoma+2 more
National Cancer Institute (NCI) 54
Early research (Phase 1)Study completedNCT00047164
What this trial is testing

Monoclonal Antibody Therapy in Treating Patients With Lymphoma or Colon Cancer That Has Not Responded to Vaccine Therapy

Who this might be right for
Lymphoma
National Institutes of Health Clinical Center (CC) 89
Testing effectiveness (Phase 2)Active Not RecruitingNCT02571725
What this trial is testing

PARP-inhibition and CTLA-4 Blockade in BRCA-deficient Ovarian Cancer

Who this might be right for
Ovarian CancerFallopian Tube CancerPeritoneal Neoplasms
New Mexico Cancer Research Alliance 50
Testing effectiveness (Phase 2)Active Not RecruitingNCT05608044
What this trial is testing

Botensilimab and Balstilimab for the Treatment of Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
Agenus Inc. 234
Testing effectiveness (Phase 2)Looking for participantsNCT05824975
What this trial is testing

Evaluate the Safety and Therapeutic Activity of GI-102 As a Single Agent and in Combination with Conventional Anti-cancer Drugs, Pembrolizumab or Trastuzumab Deruxtecan(T-DXd) in Patients with Advanced Solid Tumors (KEYNOTE-G08)

Who this might be right for
Advanced Solid TumorMetastatic Solid TumorSoft Tissue Sarcoma (STS)+6 more
GI Innovation, Inc. 358
Testing effectiveness (Phase 2)Active Not RecruitingNCT04556253
What this trial is testing

AK104 in Locally Advanced MSI-H/dMMR Gastric Carcinoma and Colorectal Cancer

Who this might be right for
MSI-H/dMMR Gastric Carcinoma and Colorectal Cancer
Peking University 47
Testing effectiveness (Phase 2)Looking for participantsNCT07315854
What this trial is testing

Iparomlimab and Tuvonralimab (QL1706) Combined With Chemotherapy for Previously Untreated Advanced or Metastatic Gastric or Gastroesophageal Junction Cancer

Who this might be right for
Gastric Cancer (GC)Gastroesophageal Junction CancerAdvanced Gastric Cancer+1 more
Beijing Friendship Hospital 32
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07533305
What this trial is testing

Efficacy and Safety of QL1706 Combined With Nab-paclitaxel and Cisplatin as 1st Line Therapy for Advanced or Metastatic Esophageal Squamous Cell Carcinoma

Who this might be right for
QL1706ESCCFirst-line Therapy
The First Affiliated Hospital of Henan University of Science and Technology 50
Not applicableStudy completedNCT03549546
What this trial is testing

Expression of the Inhibitory Receptors on Lymphocytes T Cells After Lung Cancer Surgery.

Who this might be right for
Lung CancerSurgery
Centre Hospitalier Universitaire de Saint Etienne 31
Early research (Phase 1)WithdrawnNCT00880854
What this trial is testing

Study of CP-675,206 in Bacillus Calmette-Guerin (BCG)-Resistant Bladder Cancer

Who this might be right for
Bladder Cancer
University of Wisconsin, Madison
Testing effectiveness (Phase 2)Ended earlyNCT02385669
What this trial is testing

A Phase I/II Trial to Evaluate a Peptide Vaccine Plus Ipilimumab in Patients With Melanoma

Who this might be right for
Melanoma
Craig L Slingluff, Jr 3
Testing effectiveness (Phase 2)UnknownNCT05430906
What this trial is testing

AK104 Combined With Chemotherapy as Neoadjuvant Treatment for Advanced Ovarian Cancer

Who this might be right for
Ovarian Cancer
Hunan Cancer Hospital 40
Testing effectiveness (Phase 2)Looking for participantsNCT05492123
What this trial is testing

Nivolumab-ipilimumab and Chemoradiation for Cervical Cancer

Who this might be right for
Uterine Cervical Neoplasms
Hospital Israelita Albert Einstein 112
Testing effectiveness (Phase 2)Looking for participantsNCT07289997
What this trial is testing

Iparomlimab and Tuvonralimab Combined With Apatinib and Irinotecan Hydrochloride for the Treatment of Advanced Alpha-fetoprotein-producing Gastric Cancer (AFPGC)

Who this might be right for
AFP Gastric or Gastroesophageal Junction AdenocarcinomaPD-1/CTLA-4AFPGC+1 more
Hebei Medical University Fourth Hospital 39
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