Not applicableUnknownNCT00815555What this trial is testingCYP2D6 Genotyping by AmpliChipTM CYP450 for Tamoxifen-Treated Breast Cancer PatientsWho this might be right forBreast Cancer Assaf-Harofeh Medical Center 500
Early research (Phase 1)Study completedNCT04643249What this trial is testingDrug-drug Interaction Study of KL1333 in Healthy SubjectsWho this might be right forMitochondrial Disease Abliva AB 14
Early research (Phase 1)Study completedNCT00788047What this trial is testingEvaluate The Effect Of Dimebon On The Pharmacokinetics Of DextromethorphanWho this might be right forHuntington DiseaseAlzheimer Disease Pfizer 14
Early research (Phase 1)Ended earlyNCT01289938What this trial is testingPharmacogenetic Factors and Side Effects of Metoclopramide and DiphenhydramineWho this might be right forDrug Metabolism, Poor, CYP2D6-RELATED Matthias Schwab 49
Post-approval studies (Phase 4)Active Not RecruitingNCT05657704What this trial is testingUtility of CYP2D6 Genotyping to Improve the Efficacy and Safety of TramadolWho this might be right forPost-surgical PainPain, AcutePostoperative Pain Fundación de Investigación Biomédica - Hospital Universitario de La Princesa 300
Early research (Phase 1)Study completedNCT03547024What this trial is testingA Study in Healthy Participants to Evaluate the Effects of Multiple Doses of JNJ-55308942 on Cytochrome P450 Substrate Activity and on the Pharmacokinetics of Levonorgestrel/Ethinyl EstradiolWho this might be right forHealthy Janssen-Cilag International NV 14
Not applicableUnknownNCT04249674What this trial is testingImpact of CYP2D6 Genetic Polymorphisms on the Vulnerability to Drug-drug Interactions With TramadolWho this might be right forInteractionPain University Hospital, Geneva 172
Not applicableEnded earlyNCT00981929What this trial is testingDevelopment of Cocktail for Measuring the Activity of Important Cytochrome P450 EnzymesWho this might be right forCytochrome P450 Phenotype and Genotype Metrics University of Southern Denmark 412
Early research (Phase 1)Study completedNCT02019394What this trial is testingAbsolute Bioavailability of Lu AE58054 in Healthy SubjectsWho this might be right forHealthy H. Lundbeck A/S 10
Not applicableStudy completedNCT03411759What this trial is testingCytochrome P450's Pharmacogenomics in Chronic Pain PatientsWho this might be right forAnalgesiaCYP2D6 PolymorphismOpioid Use+1 more University of Bologna 100
Not applicableStudy completedNCT01859715What this trial is testingEmergency Department (ED) Drug Interaction in Emergency Department PatientsWho this might be right forDrug Interactions University of Colorado, Denver 502
Early research (Phase 1)Study completedNCT00931073What this trial is testingA Phase I Study To Estimate The Effect Of Ketoconazole And Omeprazole On The Pharmacokinetics Of Dimebon In Healthy Subjects Who Are Normal Or Poor CYP2D6 MetabolizersWho this might be right forAlzheimer's DiseaseHuntington's Disease Pfizer 24
Post-approval studies (Phase 4)Study completedNCT03352843What this trial is testingSingle Low-dose Primaquine Efficacy and Safety.Who this might be right forMalaria Tropical Pesticides Research Institute, Tanzania 157
Early research (Phase 1)Study completedNCT06133270What this trial is testingA First Human Dose Study Investigating Safety and Concentration of Study Medicine in the Blood Following Once Daily Oral Dosing of NNC0560-0004 in Healthy Adults.Who this might be right forHealthy Volunteers - Liver Diseases Novo Nordisk A/S 51
Early research (Phase 1)Study completedNCT02929342What this trial is testingStudy to Assess the Absorption, Distribution, Metabolism and Excretion (ADME) of [14C]-Pitolisant in Healthy Male VolunteersWho this might be right forHealthy Volunteers Bioprojet 8
Early research (Phase 1)Study completedNCT00535951What this trial is testingPharmacokinetic, Safety, and Efficacy Effects of Oral LBH589 on Dextromethorphan in Patients With Advanced or Metastatic Non-Small Cell Lung Cancer or Malignant Pleural MesotheliomaWho this might be right forCarcinoma, Non-Small-Cell LungMesothelioma Novartis Pharmaceuticals 18
Early research (Phase 1)Study completedNCT02710188What this trial is testingRelative Bioavailability Study in Healthy Subjects to Evaluate the Pharmacokinetics of HTL0009936 After One Dose of Prototype FormulationWho this might be right forAlzheimer's Disease Nxera Pharma UK Limited 14
Early research (Phase 1)Study completedNCT00728468What this trial is testingTest The Impact Of PF- 00299804 On How The Body Handles Dextromethorphan In Cancer PatientsWho this might be right forAdvanced Malignant Solid Tumors Pfizer 16
Not applicableStudy completedNCT01361217What this trial is testingThe Effects of Multiple Dose Fluoxetine and Metabolites on CYP1A2, CYP2C19, CYP2D6 and CYP3A4 ActivityWho this might be right forDrug-Drug InteractionHealthy Volunteers University of Washington 10
Early research (Phase 1)Study completedNCT02264184What this trial is testingStudy to Investigate the Effect of Paroxetine Mediated CYP2D6 Inhibition on the Pharmacokinetics of Tamsulosin in Healthy Male VolunteersWho this might be right forHealthy Boehringer Ingelheim 24