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Results for “CYP2D6”

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Showing 20 of 0 results

Early research (Phase 1)Study completedNCT03072056
What this trial is testing

A Pharmacokinetic Study of MIN-101 and Its Metabolites in Healthy Subjects to Compare MIN-101 in Poor and Extensive Metabolizers

Who this might be right for
Healthy Subjects
Minerva Neurosciences 23
Early research (Phase 1)Study completedNCT02960568
What this trial is testing

Genetic Variability in CYP2D6 in U.S Active Duty Population

Who this might be right for
Pharmacologic Action
Walter Reed Army Institute of Research (WRAIR) 550
Early research (Phase 1)Study completedNCT03195946
What this trial is testing

Effects of Repeated Doses of Lu AF35700 on Drug Metabolizing Enzymes

Who this might be right for
Drug Reactions
H. Lundbeck A/S 24
Early research (Phase 1)Study completedNCT01289756
What this trial is testing

Influence of Pharmacogenetic Factors, Paroxetine and Clarithromycin on Pharmacokinetics of Clomiphene

Who this might be right for
AnovulationDisorder Due Cytochrome P450 CYP2D6 VariantCytochrome P450 CYP3A Enzyme Deficiency
Robert Bosch Gesellschaft für Medizinische Forschung mbH (RBMF) 20
Testing effectiveness (Phase 2)Study completedNCT01124695
What this trial is testing

Tamoxifen Citrate in Treating Patients With Metastatic or Recurrent Breast Cancer

Who this might be right for
Breast CancerStage IV Breast Cancer
ECOG-ACRIN Cancer Research Group 124
Post-approval studies (Phase 4)Study completedNCT00788944
What this trial is testing

Determine The Percentage Of Depressed Outpatients Who Do Not Effectively Metabolize Extended-release Venlafaxine HCl

Who this might be right for
Depression
Wyeth is now a wholly owned subsidiary of Pfizer 971
Early research (Phase 1)Study completedNCT03117660
What this trial is testing

Effects of Retinoids on CYP2D6 Activity During Pregnancy

Who this might be right for
CYP2D6 Polymorphism
University of Washington 82
Early research (Phase 1)Ended earlyNCT02209688
What this trial is testing

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ESR 1150 CL in Healthy Subjects

Who this might be right for
Healthy
Boehringer Ingelheim 39
Early research (Phase 1)Study completedNCT00727064
What this trial is testing

Study Evaluating the Pharmacokinetics of Venlafaxine Extended-Release (ER) and Desvenlafaxine Succinate Sustained-Release (DVS SR) 50 mg in Healthy Subjects

Who this might be right for
Healthy
Wyeth is now a wholly owned subsidiary of Pfizer 14
Early research (Phase 1)Study completedNCT07241065
What this trial is testing

Investigate the Effect of Capivasertib on the Pharmacokinetics of Oral Dextromethorphan (CYP2D6 Substrate) in Healthy Participants

Who this might be right for
Healthy Participants
AstraZeneca 42
Early research (Phase 1)Study completedNCT01478490
What this trial is testing

To Compare Blood and Urine Concentrations of Mirabegron (YM178) in Healthy Poor or Extensive Metabolizers for CYP2D6 and to Assess the Effect of Mirabegron on the Metabolism of Metoprolol

Who this might be right for
Pharmacokinetics of MirabegronHealthy Subjects
Astellas Pharma Inc 28
Early research (Phase 1)Study completedNCT00692510
What this trial is testing

Drug Interaction Study Between AZD3480 and Cytochrome P450

Who this might be right for
MetabolismAlzheimer's Disease
AstraZeneca 18
Large-scale testing (Phase 3)UnknownNCT03137368
What this trial is testing

Evaluate Exemestane Tablets Combined With Ovarian Function Suppression/Ablation in Treatment of Premenopausal Breast Cancer Patients With CYP2D6*10 Mutations （STEP）

Who this might be right for
CYP2D6 Polymorphism
Cancer Institute and Hospital, Chinese Academy of Medical Sciences 300
Early research (Phase 1)Study completedNCT00930306
What this trial is testing

AZD2066 Cocktail Study

Who this might be right for
Chronic Pain
AstraZeneca 15
Not applicableUnknownNCT04685304
What this trial is testing

Pharmacogenomics Applied to Chronic Pain Treatment in Primary Care

Who this might be right for
Chronic Pain
Medstar Health Research Institute 315
Not applicableStudy completedNCT01847729
What this trial is testing

OPAL: "Opiates and PhArmacoLogy"

Who this might be right for
Substance Use Disorder
Nantes University Hospital 263
Early research (Phase 1)Study completedNCT00866853
What this trial is testing

TMC435-TiDP16-C107: This Study Measures the (Possible) Influence of TMC435 on the Activity of a Selected Set of Drug-degrading Proteins by Measuring the Blood Levels of Drugs That Have Been Taken Together With TMC435 and That Are Known to be Specifically Degraded by These Drug-degrading Proteins.

Who this might be right for
Hepatitis CViruses
Tibotec Pharmaceuticals, Ireland 16
Not applicableUnknownNCT02120729
What this trial is testing

Pharmacogenetic Decision Support IT System for Psychiatric Hospitalization: RCT

Who this might be right for
Major Depressive Disorder
Hartford Hospital 1,500
Post-approval studies (Phase 4)WithdrawnNCT01529892
What this trial is testing

The Impact of Genetic Variation in CYP2D6 on the Pharmacokinetics and Pharmacodynamics of Methamphetamine

Who this might be right for
Methamphetamine Metabolism, CYP2D6 Genotype
California Pacific Medical Center Research Institute
Not applicableStudy completedNCT05966129
What this trial is testing

A Depression and Opioid Pragmatic Trial in Pharmacogenetics (Acute Pain Trial)

Who this might be right for
Acute Pain
Duke University 1,602
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