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Results for “CYP3A Inhibitor”

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Showing 20 of 0 results

Early research (Phase 1)Study completedNCT04958226
What this trial is testing

Assess the Effect of Capivasertib on Midazolam in Patients With Advanced Solid Tumours

Who this might be right for
Solid Tumour
AstraZeneca 21
Early research (Phase 1)Study completedNCT05826574
What this trial is testing

Assess Pharmacokinetics (PK) of Brensocatib Alone and With Multiple Doses of Rifampin or Esomeprozole in Healthy Participants

Who this might be right for
Healthy Volunteers
Insmed Incorporated 32
Early research (Phase 1)Study completedNCT06543043
What this trial is testing

Evaluate the Effects of Phenytoin and Itraconazole on Sonrotoclax (BGB-11417) in Healthy Volunteers

Who this might be right for
Not Determined
BeiGene 30
Early research (Phase 1)Study completedNCT04557397
What this trial is testing

Fruquintinib CYP3A Inhibitor and Inducer Study

Who this might be right for
Drug Drug Interaction
Hutchison Medipharma Limited 28
Early research (Phase 1)Study completedNCT03383692
What this trial is testing

Study of DS-8201a for Participants With Advanced Solid Malignant Tumors

Who this might be right for
Neoplasm Metastasis
Daiichi Sankyo Co., Ltd. 40
Early research (Phase 1)Study completedNCT02381080
What this trial is testing

Interaction Study of Ibrutinib and Cytochrome P450 (CYP) 3A Inhibitors in Participants With B-cell Malignancy

Who this might be right for
B-Cell Chronic Lymphocytic Leukemia
Janssen Research & Development, LLC 26
Early research (Phase 1)Study completedNCT03499106
What this trial is testing

A Trial to Evaluate the Effect of Itraconazole (ITZ), a CYP3A4 Inhibitor, on the Pharmacokinetics of Praliciguat (IW-1973) in Healthy Volunteers

Who this might be right for
Healthy
Cyclerion Therapeutics 24
Early research (Phase 1)Study completedNCT02809768
What this trial is testing

Study to Assess Pharmacokinetic Drug-Drug Interaction Between Avatrombopag When Co-Administered With Fluconazole, Itraconazole, or Rifampin in Healthy Subjects

Who this might be right for
Healthy Participants
Eisai Inc. 48
Early research (Phase 1)Study completedNCT01984229
What this trial is testing

The Effects of Posaconazole on Alectinib (RO5424802) Pharmacokinetics in Healthy Volunteers

Who this might be right for
Healthy Volunteer
Hoffmann-La Roche 23
Early research (Phase 1)Study completedNCT03961997
What this trial is testing

Effect of Multiple Doses of Modafinil on the Pharmacokinetics of Single Dose Lorlatinib in Healthy Participants

Who this might be right for
AdultDrug InteractionsHealthy Volunteers+1 more
Pfizer 16
Early research (Phase 1)Study completedNCT04510649
What this trial is testing

Surufatinib DDI With a PPI and a CYP3A Inducer

Who this might be right for
Healthy
Hutchison Medipharma Limited 28
Early research (Phase 1)Study completedNCT03892499
What this trial is testing

A Trial to Evaluate the Effect of Itraconazole (ITZ), a CYP3A4 Inhibitor, on the Pharmacokinetics of the Soluble Guanylate Cyclase Stimulator, Olinciguat (IW-1701), in Healthy Volunteers

Who this might be right for
Healthy
Cyclerion Therapeutics 24
Early research (Phase 1)Looking for participantsNCT07590102
What this trial is testing

Investigate the Effect of the CYP3A Inducer Phenytoin and the CYP3A Inhibitor Itraconazole on the Pharmacokinetics of BGB-58067 in Healthy Participants

Who this might be right for
Healthy Volunteers
BeOne Medicines 30
Early research (Phase 1)Not Yet RecruitingNCT07745439
What this trial is testing

A Drug-Drug Interaction Study Between NTQ5082 Capsules and Midazolam Oral Solutio

Who this might be right for
Healthy VolunteersDrug-Drug Interaction (DDI)
The Third Xiangya Hospital of Central South University 18
Early research (Phase 1)Study completedNCT03451110
What this trial is testing

Study to Assess the Pharmacokinetic Drug-Drug Interactions of Lemborexant When Coadministered With an Oral Contraceptive, Famotidine, or Fluconazole in Healthy Subjects

Who this might be right for
Healthy Subjects
Eisai Inc. 50
Early research (Phase 1)Study completedNCT03535662
What this trial is testing

A Pharmacokinetic Study of the Effect of Itraconazole Exposure to Orvepitant in Healthy Volunteers

Who this might be right for
Pharmacokinetic Study in Healthy Male Volunteers
Nerre Therapeutics Ltd. 16
Early research (Phase 1)Study completedNCT02259010
What this trial is testing

Evaluate the Effect of Itraconazole on the Pharmacokinetics of Alisertib in Participants With Advanced Solid Tumors or Relapsed/Refractory Lymphoma

Who this might be right for
Advanced Solid TumorsRelapsed/Refractory Lymphoma
Millennium Pharmaceuticals, Inc. 24
Testing effectiveness (Phase 2)WithdrawnNCT05545319
What this trial is testing

Learn About the Medicine Called Nirmatrelvir Used in Combination With Ritonavir in People With Weakened Immune Systems or at Increased Risk for Poor Outcomes Who Are Hospitalized Due to Severe COVID-19

Who this might be right for
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)Coronavirus Disease 2019 (COVID-19)Immunocompromised+2 more
Pfizer
Early research (Phase 1)Study completedNCT04551963
What this trial is testing

Interaction Study of Zanubrutinib With Moderate and Strong CYP3A Inhibitors in Participants With B-Cell Malignancies

Who this might be right for
B-cell Malignancies
BeiGene 26
Early research (Phase 1)Study completedNCT06906809
What this trial is testing

Effect of Phenytoin or Itraconazole on How BGB-16673 is Absorbed and Removed From the Body in Healthy Participants

Who this might be right for
Healthy Volunteers
BeiGene 37
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