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Results for “CYP3A4 Induction”

42 trials

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Showing 20 of 42 results

Not applicableStudy completedNCT01258504
What this trial is testing

Influence of CYP3A4-induction by St. John's Wort on the Steady State Pharmacokinetics of Bosentan

Who this might be right for
Drug Interactions
Gerd Mikus 13
Not applicableStudy completedNCT02191358
What this trial is testing

YouScript IMPACT Registry

Who this might be right for
Adverse Drug EventsAdverse Drug ReactionsDrug Interaction Potentiation+10 more
Genelex Corporation 800
Early research (Phase 1)Study completedNCT05760261
What this trial is testing

Drug Interaction Assessment of GSK3882347 in Healthy Participants Aged 18 to 65 Years

Who this might be right for
Urinary Tract Infections
GlaxoSmithKline 27
Early research (Phase 1)Study completedNCT06689527
What this trial is testing

Evaluation of Vamorolone CYP3A4 Induction on Midazolam (a Sensitive CYP 3A4 Substrate) Pharmacokinetics

Who this might be right for
Drug Interaction
Santhera Pharmaceuticals 18
Early research (Phase 1)Study completedNCT02545439
What this trial is testing

A Drug-drug Interaction Study of ALKS 5461 in Healthy Volunteers

Who this might be right for
Healthy Volunteers
Alkermes, Inc. 24
Early research (Phase 1)Study completedNCT01910311
What this trial is testing

Baricitinib and Rifampicin in Healthy Participants

Who this might be right for
Healthy Volunteers
Eli Lilly and Company 18
Early research (Phase 1)Study completedNCT00440128
What this trial is testing

The Effects Of GW679769 (Casopitant) On The Pharmacokinetics Of Docetaxel In Subjects With Cancer

Who this might be right for
Nausea and Vomiting, Chemotherapy-Induced
GlaxoSmithKline 12
Early research (Phase 1)Study completedNCT03723395
What this trial is testing

A Drug-Drug Interaction Study in Healthy Volunteers of the Effects of Tucatinib

Who this might be right for
Drug-drug Interaction
Seagen Inc. 116
Post-approval studies (Phase 4)Study completedNCT01519726
What this trial is testing

CYP3A4 Metabolism Before and After Surgery Induced Weight Loss Using Midazolam as Model Drug

Who this might be right for
Morbid Obesity
St. Antonius Hospital 20
Early research (Phase 1)Study completedNCT02975440
What this trial is testing

Drug-drug Interaction Study Between Orally Administered Rifampicin and Vilaprisan

Who this might be right for
Endometriosis
Bayer 12
Early research (Phase 1)Study completedNCT02138799
What this trial is testing

Evaluate How a Drug That Alters Liver Enzymes (Rifampin) Affects the Metabolism of Enzalutamide in Men

Who this might be right for
Drug-Drug Interaction (DDI)Healthy SubjectsPharmacokinetics of Enzalutamide
Astellas Pharma Europe B.V. 28
Not applicableStudy completedNCT02378220
What this trial is testing

Pharmacogenetic Testing Among Home Health Patients

Who this might be right for
Adverse Drug EventsAdverse Drug ReactionsDrug Interaction Potentiation+10 more
Genelex Corporation 110
Early research (Phase 1)Study completedNCT06194864
What this trial is testing

Drug Interaction Study

Who this might be right for
Drug Interaction
Emalex Biosciences Inc. 45
Early research (Phase 1)Study completedNCT02434861
What this trial is testing

An Open Label, Single Dose, Three Part Study to Assess the Effects of Rolapitant (2 mg/mL IV Solution) on the Pharmacokinetics of Digoxin; Sulfasalazine; and the Cooperstown Cocktail (Midazolam, Omeprazole, Warfarin, Caffeine, and Dextromethorphan in Healthy Subjects

Who this might be right for
Chemotherapy-induced Nausea and Vomiting
Tesaro, Inc. 102
Not applicableStudy completedNCT01311362
What this trial is testing

Influence of Cytochrome CYP3A4-induction by St. John's Wort on the Steady State Pharmacokinetics of Ambrisentan

Who this might be right for
Drug Interactions
Gerd Mikus 20
Early research (Phase 1)UnknownNCT00504413
What this trial is testing

Role of CYP2B6, CYP3A4, and MDR1 in the Metabolic Clearance of Methadone

Who this might be right for
Substance-Related Disorders
University of Washington 20
Early research (Phase 1)Study completedNCT06919991
What this trial is testing

Drug-Drug Interaction Study of Casdatifan in Healthy Adult Participants (ARC-29)

Who this might be right for
Healthy Participants
Arcus Biosciences, Inc. 14
Early research (Phase 1)Study completedNCT03195946
What this trial is testing

Effects of Repeated Doses of Lu AF35700 on Drug Metabolizing Enzymes

Who this might be right for
Drug Reactions
H. Lundbeck A/S 24
Early research (Phase 1)Study completedNCT00621309
What this trial is testing

Sulforaphane as an Antagonist to Human PXR-mediated Drug-drug Interactions

Who this might be right for
Adverse Drug Interactions
University of Washington 29
Early research (Phase 1)Study completedNCT01323465
What this trial is testing

Study to Evaluate the Effect of Rifampicin, Ketoconazole, and Omeprazole on the Pharmacokinetics of Sativex

Who this might be right for
Evaluation of Pharmacokinetics of Sativex in the Absence and Presence of a Known Inducer of CYP3A4Evaluation of Pharmacokinetics of Sativex in the Absence and Presence of a Potent Inhibitor of CYP3A4Evaluation of Pharmacokinetics of Sativex in the Absence and Presence of a CYP2C19 Inhibitor
Jazz Pharmaceuticals
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