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Results for “Chimeric Antigen Receptor T-Cell Therapy (CAR-T) Cytokine Release Syndrome (CRS)”

13 trials

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Showing 13 of 13 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT04975555
What this trial is testing

Study to Evaluate the Role of Siltuximab in Treatment of Cytokine Release Syndrome (CRS) and Immune Effector Cell Associated Neurotoxicity (ICANS) Related to CAR-T Cell Therapy

Who this might be right for
Cytokine Release SyndromeICANSLymphoma, Non-Hodgkin+2 more
University of Alabama at Birmingham 30
Not applicableLooking for participantsNCT05146336
What this trial is testing

CytOSorb TreatMent Of Critically Ill PatientS Registry

Who this might be right for
Septic ShockAcute Respiratory Distress SyndromeTrauma+15 more
CytoSorbents, Inc 3,000
Testing effectiveness (Phase 2)Study completedNCT04359784
What this trial is testing

Anakinra for the Prevention of Cytokine Release Syndrome and Neurotoxicity in Patients With B-Cell Non-Hodgkin Lymphoma Receiving CD19-Targeted CAR-T Cell Therapy

Who this might be right for
B-Cell Non-Hodgkin Lymphoma
Fred Hutchinson Cancer Center 27
Not applicableUnknownNCT04822974
What this trial is testing

TORQUETENOVIRUS IN CAR-T THERAPY: PREDICTION OF THE CRS

Who this might be right for
Hematologic Cancer
Institut Paoli-Calmettes 20
Testing effectiveness (Phase 2)UnknownNCT03275493
What this trial is testing

CD19 CAR-T Cells With CRS Suppression Technology for r/r CD19+ Acute Lymphoblastic Leukemia

Who this might be right for
Acute Lymphoblastic LeukemiaCD19 PositiveRelapse+1 more
Shanghai Unicar-Therapy Bio-medicine Technology Co.,Ltd 40
Early research (Phase 1)Looking for participantsNCT07169487
What this trial is testing

Adjunctive Methylene Blue for Immunotherapy-related CRS and ICANS: Phase I Study

Who this might be right for
Cytokine Release SyndromeICANS
Institute of Hematology & Blood Diseases Hospital, China 18
Large-scale testing (Phase 3)Looking for participantsNCT07502118
What this trial is testing

NexCAR19 (Talikabtagene Autoleucel) in Relapsed/Refractory B-Cell Malignancies (NexCAR19)

Who this might be right for
Relapsed/Refractory B-cell Acute Lymphoblastic Leukemia (B-ALL)Relapsed/Refractory Non-Hodgkin LymphomaDiffuse Large B-Cell Lymphoma (DLBCL)+2 more
Health Institutes of Turkey 40
Not applicableUnknownNCT05414162
What this trial is testing

Multiparametric Cardiac MRI in Patients Under CAR T-cell Therapy

Who this might be right for
DLBCLMultiple MyelomaCytokine Release Syndrome+6 more
University Hospital, Bonn 60
Early research (Phase 1)Not Yet RecruitingNCT07166549
What this trial is testing

Bispecific CAR T Cells for B-cell Malignancies (BaseCAR-01 Trial)

Who this might be right for
B Cell MalignanciesB-cell LeukemiaB Cell Lymphoma+2 more
University Hospital, Basel, Switzerland 12
Not applicableStudy completedNCT06415656
What this trial is testing

VitalTraq for the Detection of CRS

Who this might be right for
Hematologic Malignancy
Duke University 32
Not applicableUnknownNCT04048434
What this trial is testing

Extracorporeal Cytokine Adsorption as Additive Treatment of CAR-T Associated Cytokine Release Syndrome (CRS)

Who this might be right for
Cytokine Release SyndromeCAR-T
Hannover Medical School 34
Testing effectiveness (Phase 2)Looking for participantsNCT05905328
What this trial is testing

Study of CTO1681 for the Prevention and Treatment of CRS in DLBCL Patients Receiving CAR T-Cell Therapy

Who this might be right for
Cytokine Release Syndrome
CytoAgents, Inc. 54
Very early researchLooking for participantsNCT05306080
What this trial is testing

Tadekinig Alfa (IL-18BP) Rescue Therapy for CAR T Cell Related Cytokine Release Syndrome (CRS) and HLH-like Syndrome

Who this might be right for
CRS - Cytokine Release SyndromeHLH
University of Pennsylvania 10