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Results for “Chronic Hepatic Impairment”

30 trials

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Showing 20 of 30 results

Early research (Phase 1)Study completedNCT00781430
What this trial is testing

Study Evaluating The PK And Safety Of Neratinib In Healthy Subjects And Subjects With Chronic Liver Disease

Who this might be right for
Hepatic Insufficiency
Puma Biotechnology, Inc. 27
Early research (Phase 1)Study completedNCT03814005
What this trial is testing

Pevonedistat in People With Blood Cancers or Solid Tumors With Kidney or Liver Problems

Who this might be right for
Myelodysplastic SyndromesLeukemia, Myelomonocytic, ChronicLeukemia, Myeloid, Acute+3 more
Takeda 17
Early research (Phase 1)Ended earlyNCT00004239
What this trial is testing

506U78 in Treating Patients With Hematologic Cancer and Kidney or Liver Impairment

Who this might be right for
Chronic Myeloproliferative DisordersLeukemiaLymphoma+2 more
Alliance for Clinical Trials in Oncology 10
Early research (Phase 1)Study completedNCT00314054
What this trial is testing

Study Evaluating the Safety of HCV-796 in Subjects With Liver Disease and in Healthy Adults

Who this might be right for
Hepatitis CHepatic Insufficiency
Wyeth is now a wholly owned subsidiary of Pfizer 27
Early research (Phase 1)Study completedNCT00359463
What this trial is testing

Study Of Eltrombopag in Healthy Subjects and Volunteers With Mild, Moderate or Severe Hepatic Impairment

Who this might be right for
Purpura, Thrombocytopaenic, Idiopathic
GlaxoSmithKline 33
Early research (Phase 1)Study completedNCT02095587
What this trial is testing

Duvelisib in Hepatically Impaired Subjects Compared to Healthy Subjects

Who this might be right for
Hepatic Impairment
SecuraBio 24
Early research (Phase 1)Study completedNCT01465412
What this trial is testing

Assess Pharmacokinetics of Preladenant in Participants With Chronic Hepatic Impairment (P06513)

Who this might be right for
Chronic Hepatic Impairment
Merck Sharp & Dohme LLC 42
Early research (Phase 1)Study completedNCT06736223
What this trial is testing

Pharmacokinetics, Safety and Tolerability of ITF2357 in Participants With Chronic Hepatic Impairment and With Normal Hepatic Function

Who this might be right for
Hepatic Impairment
Italfarmaco 24
Early research (Phase 1)Study completedNCT01817985
What this trial is testing

Evaluate the Pharmacokinetics of GS-5816 in Subjects With Normal Hepatic Function and Moderate or Severe Hepatic Impairment

Who this might be right for
Chronic Hepatitis C
Gilead Sciences 33
Testing effectiveness (Phase 2)Ended earlyNCT05900050
What this trial is testing

Efficacy, Safety and Tolerability of VS-01 in Adult Patients With Acute-on-Chronic Liver Failure and Ascites (UNVEIL-IT)®

Who this might be right for
Acute-On-Chronic Liver FailureAscites
Genfit 15
Not applicableStudy completedNCT00424957
What this trial is testing

Brain Energy Metabolism in Patients With Chronic Liver Disease and Impaired Central Nervous System

Who this might be right for
CirrhosisHepatic Encephalopathy
University of Aarhus 18
Early research (Phase 1)Study completedNCT00118170
What this trial is testing

Sorafenib in Treating Patients With Metastatic or Unresectable Solid Tumors, Multiple Myeloma, or Non-Hodgkin's Lymphoma With or Without Impaired Liver or Kidney Function

Who this might be right for
Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid TissueNodal Marginal Zone B-cell LymphomaRecurrent Adult Burkitt Lymphoma+42 more
National Cancer Institute (NCI) 150
Testing effectiveness (Phase 2)Study completedNCT01830127
What this trial is testing

BI 207127 / Faldaprevir Combination Therapy in Hepatic Impairment (Child-Pugh B) Patients With Genotype 1b Chronic Hepatitis C Infection: HCVerso3

Who this might be right for
Hepatitis C, Chronic
Boehringer Ingelheim 35
Early research (Phase 1)Study completedNCT01577680
What this trial is testing

Assess the Effects of GSK573719/VI Combination and GSK573719 Monotherapy in Subjects With Moderate Hepatic Impairment and Matched Healthy Volunteers

Who this might be right for
Pulmonary Disease, Chronic Obstructive
GlaxoSmithKline 18
Early research (Phase 1)Study completedNCT01497327
What this trial is testing

Open-Label Hepatic Impairment Study

Who this might be right for
Hepatitis C
Gilead Sciences 24
Not applicableStudy completedNCT00305591
What this trial is testing

Brain Imaging in Patients With Chronic Liver Disease and Functional Impairment.

Who this might be right for
CirrhosisHepatic Encephalopathy
Imperial College London 50
Early research (Phase 1)Study completedNCT00759837
What this trial is testing

Study Evaluating The Pharmacokinetics (PK) And Safety Of Bosutinib In Subjects With Liver Disease And In Healthy Subjects

Who this might be right for
Breast CancerLeukemia, Myeloid, Chronic
Wyeth is now a wholly owned subsidiary of Pfizer 27
Early research (Phase 1)Looking for participantsNCT07342868
What this trial is testing

Single-Dose Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Pevifoscorvir Sodium (ALG-000184) in Subjects With Moderate Hepatic Impairment and in Healthy Subjects With Normal Hepatic Function

Who this might be right for
Chronic Hepaititis B Infections
Aligos Therapeutics 16
Early research (Phase 1)Study completedNCT00805090
What this trial is testing

Open-Label, Single-Dose Study to Evaluate the Safety and PK of DIC075V in Subjects With Renal Insufficiency and Hepatic Impairment Compared to Healthy Subjects and Evaluate the Safety and Pharmacokinetics of HPβCD When Administered in DIC075V Compared to Sporanox® in Healthy Subjects

Who this might be right for
Renal Insufficiency, ChronicHepatic InsufficiencyHealthy
Javelin Pharmaceuticals 37
Post-approval studies (Phase 4)Study completedNCT01846455
What this trial is testing

Single Dose Pharmacokinetics of Suboxone Study in Hepatic Impaired Subjects

Who this might be right for
Hepatic FailureHepatic ImpairmentChronic Hepatitis C Infection With Hepatic Coma
Indivior Inc. 43
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