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Results for “Chronic Hepatic Impairment”

30 trials

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Showing 20 of 30 results

Early research (Phase 1)Study completedNCT01919125
What this trial is testing

Pharmacokinetics of IDX719 in Participants With Normal and Impaired Hepatic Function (MK-1894-008)

Who this might be right for
Hepatitis C, Chronic
Merck Sharp & Dohme LLC 36
Early research (Phase 1)Study completedNCT05624710
What this trial is testing

Evaluate the Pharmacokinetics and Safety of INCB054707 in Participants With Normal Hepatic Function and Participants With Hepatic Impairment

Who this might be right for
Renal InsufficiencyKidney Diseases
Incyte Corporation 25
Early research (Phase 1)Study completedNCT01817985
What this trial is testing

Evaluate the Pharmacokinetics of GS-5816 in Subjects With Normal Hepatic Function and Moderate or Severe Hepatic Impairment

Who this might be right for
Chronic Hepatitis C
Gilead Sciences 33
Early research (Phase 1)Study completedNCT03814005
What this trial is testing

Pevonedistat in People With Blood Cancers or Solid Tumors With Kidney or Liver Problems

Who this might be right for
Myelodysplastic SyndromesLeukemia, Myelomonocytic, ChronicLeukemia, Myeloid, Acute+3 more
Takeda 17
Early research (Phase 1)Study completedNCT06402721
What this trial is testing

Learn About How BAY 3283142 Moves Into, Through, and Out of the Body After a Single Dose in Participants With Reduced Liver Function Compared to Participants With Normal Liver Function

Who this might be right for
Chronic Kidney DiseaseHepatic Impairment
Bayer 24
Early research (Phase 1)Study completedNCT00314054
What this trial is testing

Study Evaluating the Safety of HCV-796 in Subjects With Liver Disease and in Healthy Adults

Who this might be right for
Hepatitis CHepatic Insufficiency
Wyeth is now a wholly owned subsidiary of Pfizer 27
Not applicableStudy completedNCT00305591
What this trial is testing

Brain Imaging in Patients With Chronic Liver Disease and Functional Impairment.

Who this might be right for
CirrhosisHepatic Encephalopathy
Imperial College London 50
Early research (Phase 1)Study completedNCT00759837
What this trial is testing

Study Evaluating The Pharmacokinetics (PK) And Safety Of Bosutinib In Subjects With Liver Disease And In Healthy Subjects

Who this might be right for
Breast CancerLeukemia, Myeloid, Chronic
Wyeth is now a wholly owned subsidiary of Pfizer 27
Early research (Phase 1)Study completedNCT04881994
What this trial is testing

Learn How Finerenone (BAY94-8862) Moves Into, Through and Out of the Body, How it Affects the Body, and How Safe it is in Adult Participants With Different Degrees of Reduced Liver Function and in Healthy Participants With Similar Age, Weight and Gender Distribution

Who this might be right for
Worsening Chronic Heart FailureDiabetic Nephropathy
Bayer 27
Early research (Phase 1)Study completedNCT06736223
What this trial is testing

Pharmacokinetics, Safety and Tolerability of ITF2357 in Participants With Chronic Hepatic Impairment and With Normal Hepatic Function

Who this might be right for
Hepatic Impairment
Italfarmaco 24
Testing effectiveness (Phase 2)Study completedNCT01830127
What this trial is testing

BI 207127 / Faldaprevir Combination Therapy in Hepatic Impairment (Child-Pugh B) Patients With Genotype 1b Chronic Hepatitis C Infection: HCVerso3

Who this might be right for
Hepatitis C, Chronic
Boehringer Ingelheim 35
Early research (Phase 1)Study completedNCT04454424
What this trial is testing

Study on the Safety of BAY1817080, How it is Tolerated and the Way the Body Absorbs, Distributes and Gets Rid of the Study Drug in Participants With Impaired Liver Function or Normal Liver Function

Who this might be right for
Endometriosis Related PainOveractive BladderDiabetic Neuropathic Pain+1 more
Bayer 37
Early research (Phase 1)Ended earlyNCT00004239
What this trial is testing

506U78 in Treating Patients With Hematologic Cancer and Kidney or Liver Impairment

Who this might be right for
Chronic Myeloproliferative DisordersLeukemiaLymphoma+2 more
Alliance for Clinical Trials in Oncology 10
Testing effectiveness (Phase 2)Ended earlyNCT05900050
What this trial is testing

Efficacy, Safety and Tolerability of VS-01 in Adult Patients With Acute-on-Chronic Liver Failure and Ascites (UNVEIL-IT)®

Who this might be right for
Acute-On-Chronic Liver FailureAscites
Genfit 15
Not applicableLooking for participantsNCT07418008
What this trial is testing

The Liver Cirrhosis Cognitive Decline Scale (LiCCoS)

Who this might be right for
Liver CirrhosisCognitive DysfunctionHepatic Encephalopathy+1 more
University of Malaya 230
Early research (Phase 1)Study completedNCT00805090
What this trial is testing

Open-Label, Single-Dose Study to Evaluate the Safety and PK of DIC075V in Subjects With Renal Insufficiency and Hepatic Impairment Compared to Healthy Subjects and Evaluate the Safety and Pharmacokinetics of HPβCD When Administered in DIC075V Compared to Sporanox® in Healthy Subjects

Who this might be right for
Renal Insufficiency, ChronicHepatic InsufficiencyHealthy
Javelin Pharmaceuticals 37
Early research (Phase 1)Looking for participantsNCT07342868
What this trial is testing

Single-Dose Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Pevifoscorvir Sodium (ALG-000184) in Subjects With Moderate Hepatic Impairment and in Healthy Subjects With Normal Hepatic Function

Who this might be right for
Chronic Hepaititis B Infections
Aligos Therapeutics 16
Early research (Phase 1)Not Yet RecruitingNCT07394309
What this trial is testing

Study of Hydroxynidone Capsules in Patients With Hepatic Impairment and Matched Healthy Controls

Who this might be right for
Liver Fibrosis
Beijing Continent Pharmaceutical Co, Ltd. 30
Testing effectiveness (Phase 2)Study completedNCT03180619
What this trial is testing

Study to Evaluate the Safety and Efficacy of Switching to Tenofovir Alafenamide (TAF) From Tenofovir Disoproxil Fumarate (TDF) and/or Other Oral Antiviral Treatment (OAV)

Who this might be right for
Chronic Hepatitis B
Gilead Sciences 124
Early research (Phase 1)Study completedNCT00359463
What this trial is testing

Study Of Eltrombopag in Healthy Subjects and Volunteers With Mild, Moderate or Severe Hepatic Impairment

Who this might be right for
Purpura, Thrombocytopaenic, Idiopathic
GlaxoSmithKline 33
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