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Results for “Controlled Human Malaria Infection”

71 trials

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Showing 20 of 71 results

Early research (Phase 1)Active Not RecruitingNCT06735209
What this trial is testing

First-in-Human PfSPZ-LARC2 Vaccination/CHMI

Who this might be right for
Malaria
National Institute of Allergy and Infectious Diseases (NIAID) 22
Testing effectiveness (Phase 2)Study completedNCT02692963
What this trial is testing

Safety and Protective Efficacy of BCG Vaccination Against Controlled Human Malaria Infection

Who this might be right for
MalariaPlasmodium Falciparum
Radboud University Medical Center 20
Early research (Phase 1)Not Yet RecruitingNCT06293339
What this trial is testing

Durability of Protection After Single Immunisation With GA2 Sporozoites (CoGA-Rechallenge)

Who this might be right for
Malaria,Falciparum
Leiden University Medical Center 14
Testing effectiveness (Phase 2)Study completedNCT05816330
What this trial is testing

L9LS MAb in Malian Adults

Who this might be right for
Plasmodium Falciparum InfectionMalaria
National Institute of Allergy and Infectious Diseases (NIAID) 490
Testing effectiveness (Phase 2)Study completedNCT06069544
What this trial is testing

A Clinical Trial to Evaluate the Safety, Efficacy and Immune Responses After Vaccination With an Investigational RNA-based Vaccine Against Malaria

Who this might be right for
Malaria
BioNTech SE 163
Early research (Phase 1)Study completedNCT05019729
What this trial is testing

Trial to Evaluate L9LS in Healthy Adults

Who this might be right for
Malaria
National Institute of Allergy and Infectious Diseases (NIAID) 32
Early research (Phase 1)Study completedNCT02562872
What this trial is testing

DSM265 Prophylaxis of Plasmodium Falciparum Malaria

Who this might be right for
Healthy
Medicines for Malaria Venture 24
Testing effectiveness (Phase 2)Study completedNCT03138096
What this trial is testing

Safety and Protective Efficacy of Pb(PfCS@UIS4)

Who this might be right for
Malaria,FalciparumPlasmodium FalciparumPlasmodium Berghei+1 more
Radboud University Medical Center 24
Early research (Phase 1)Study completedNCT05891236
What this trial is testing

Safety, Tolerability, Pharmacokinetics and Protective Efficacy of MAM01 in Healthy Adults

Who this might be right for
Malaria
Gates Medical Research Institute 61
Early research (Phase 1)UnknownNCT02739763
What this trial is testing

Controlled Human Malaria Infection in Semi-Immune Kenyan Adults. (CHMI-SIKA)

Who this might be right for
Malaria
University of Oxford 200
Early research (Phase 1)Study completedNCT02859350
What this trial is testing

Safety, Tolerability and Immunogenicity of PfSPZ Vaccine in an Age De-escalation Trial in Equatorial Guinea.

Who this might be right for
Malaria
Sanaria Inc. 135
Early research (Phase 1)UnknownNCT04296279
What this trial is testing

A Trial For The Study of Falciparum Malaria Protein 014 Administered Via Intramuscular Injection in Healthy Adults

Who this might be right for
Vaccine Reaction
U.S. Army Medical Research and Development Command 46
Early research (Phase 1)Study completedNCT01624961
What this trial is testing

Controlled Human Malarial Infection by Intravenous Injection of Plasmodium Falciparum Sporozoites in Non-Immune Adults

Who this might be right for
Malaria
Sanaria Inc. 30
Early research (Phase 1)Study completedNCT03867331
What this trial is testing

To Assess the Safety, Immunogenicity and Efficacy of VLPM01 in Healthy, Malaria-Naïve Volunteers

Who this might be right for
Malaria,Falciparum
VLP Therapeutics 36
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07373301
What this trial is testing

Phase IIa/b Trial of PvCS/Montanide ISA-51 Malaria Vaccine in Adults in Chocó, Colombia

Who this might be right for
Plasmodium Vivax MalariaPlasmodium Vivax InfectionMalaria Prevention
Malaria Vaccine and Drug Development Center 72
Testing effectiveness (Phase 2)Study completedNCT02601716
What this trial is testing

PfSPZ Vaccine: Dose Optimization With Heterologous Challenge in Healthy Malaria-Naïve Adults

Who this might be right for
Malaria
Sanaria Inc. 92
Early research (Phase 1)Looking for participantsNCT06862453
What this trial is testing

Safety, Tolerability and Efficacy Against Controlled Human Malaria Infection of PfSPZ-LARC2 Vaccine in Malaria-naïve Adults

Who this might be right for
Malaria Falciparum
Sanaria Inc. 58
Early research (Phase 1)Study completedNCT01728701
What this trial is testing

Controlled Human Malaria Infection (CHMI) After Immunization With Cryopreserved Plasmodium Falciparum Sporozoites Under Chloroquine Prophylaxis

Who this might be right for
MalariaPlasmodium Falciparum
Sanaria Inc. 30
Early research (Phase 1)UnknownNCT04268420
What this trial is testing

A Trial For The Study of Falciparum Malaria Protein 013 Administered Via Intramuscular Injection in Healthy Adults

Who this might be right for
Vaccine Reaction
U.S. Army Medical Research and Development Command 46
Not applicableEnded earlyNCT03813108
What this trial is testing

Safety and Efficacy of NF135 CPS Immunization

Who this might be right for
Malaria,FalciparumControlled Human Malaria InfectionImmunization; Infection
Radboud University Medical Center 43
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