Early research (Phase 1)Study completedNCT00346853What this trial is testingPhase 1 Pilot Study of 4-MP to Treat Stargardt Macular DystrophyWho this might be right forMacular Dystrophy, Corneal University of Utah 10
Early research (Phase 1)Study completedNCT05769920What this trial is testingDose Escalation TTHX1114 Ophthalmic SolutionWho this might be right forCorneal Epithelial Degeneration Trefoil Therapeutics, Inc. 8
Not applicableUnknownNCT05875909What this trial is testingCorneal Flap Transplantation for Macular Hole Repair of High MyopiaWho this might be right forRetinal PerforationsMyopia, Degenerative First People's Hospital of Hangzhou 30
Not applicableEnded earlyNCT01189864What this trial is testingCross-linking of Corneal Collagen (CXL) With Ultraviolet-A in Asymmetric CorneasWho this might be right forKeratoconusEctasiaDegeneration Cxlusa 3,493
Not applicableNo Longer AvailableNCT01384773What this trial is testingProgressive Keratoconus or Ectasia Treatment PlanWho this might be right forKeratoconusEctasia Stephen Trokel
Not applicableStudy completedNCT02811692What this trial is testingStudy for Collection of Aflibercept Data in Routine PracticeWho this might be right forEye Diseases Bayer 425
Testing effectiveness (Phase 2)UnknownNCT04401865What this trial is testingSafety and Effectiveness of the PXL-Platinum 330 SystemWho this might be right forCorneal EctasiaKeratoconusPellucid Marginal Corneal Degeneration Colorado Eye Consultants/Cornea Consultants of Colorado 300
Not applicableEnded earlyNCT04527523What this trial is testingDescemet Membrane Endothelial Keratoplasty vs. Descemet's Stripping With Endothelial Keratoplasty vs. Descemet Stripping OnlyWho this might be right forCystoid Macular EdemaFuchs Dystrophy Wake Forest University Health Sciences 4
Not applicableEnded earlyNCT01067742What this trial is testingThe Natural History of Mucolipidosis Type IVWho this might be right forMucolipidosis Type IV Baylor Research Institute 7
Not applicableStudy completedNCT00396188What this trial is testingScreening Aid to Identify Corneas That May Have Pathologies or Other ConditionsWho this might be right forCorneal Diseases Carl Zeiss Meditec, Inc. 769
Large-scale testing (Phase 3)Looking for participantsNCT07135167What this trial is testingCompassionate Use Study of Epi-ON Corneal Collagen Crosslinking Performed Using UVA Exposure on Eyes With Ectatic Corneal Diseases for Subjects With Down SyndromeWho this might be right forDown Syndrome (DS)KeratoconusPellucid Marginal Degeneration+1 more Woolfson Eye Institute 225
Testing effectiveness (Phase 2)Looking for participantsNCT04094090What this trial is testingSafety and Effectiveness of the PXL-Platinum 330 System for Corneal Cross-Linking in Eyes With Corneal EctasiaWho this might be right forKeratoconusPellucid Marginal Corneal DegenerationCorneal Ectasia Goodman Eye Center 500
Not applicableEnded earlyNCT01097447What this trial is testingCollagen Crosslinking With Ultraviolet-A in Asymmetric Corneas (2)Who this might be right forKeratoconusEctasiaDegeneration Cxlusa 2,619
Not applicableUnknownNCT00623584What this trial is testingComparison of Corneal Grafts Cultured in Serum-free Versus Corneal Grafts Cultured in Serum Supplemented Culture MediaWho this might be right forFuch's Endothelial DystrophyPseudophakic Bullous Keratopathy Klinikum Chemnitz gGmbH 60
Not applicableEnded earlyNCT01024322What this trial is testingCollagen Crosslinking With Ultraviolet-A in Asymmetric CorneasWho this might be right forKeratoconusEctasiaDegeneration Cxlusa 1,189
Not applicableStudy completedNCT04023123What this trial is testingAnterior Corneal Striae in HypotonyWho this might be right forHypotony OcularCornea Folds and Rupture of Bowman's Membrane Both EyesMaculopathy Duke University 98
Not applicableStudy completedNCT03220529What this trial is testingTest the Potential of Brillouin Microscopy for Biomechanical Properties Measurements in Human CorneaWho this might be right forPellucid Marginal Corneal DegenerationKeratoconusKeratectasia Massachusetts General Hospital 85
Large-scale testing (Phase 3)UnknownNCT00815256What this trial is testingSafety and Effectiveness of Collagen Cross Linking in Progressive Mild and Moderate KeratoconusWho this might be right forCornea DegenerationProgressive Keratoconus Federal University of São Paulo 15
Not applicableUnknownNCT02614625What this trial is testingSpectral-domain Optical Coherence Tomography of the EyeWho this might be right forCorneaRetinaRefractive Surgery+3 more Augenabteilung Allgemeines Krankenhaus Linz 100
Post-approval studies (Phase 4)Study completedNCT01573572What this trial is testingExtension Study to Gather Data on Effect of Macugen on the Corneal EndotheliumWho this might be right forAge-Related Macular DegenerationRetinal Vein OcclusionDiabetic Macular Edema Bausch & Lomb Incorporated 131