Early research (Phase 1)Active Not RecruitingNCT02379338What this trial is testingStudy of Radiotracer [18F]Fluortriopride ([18F]FTP) by PET/CTWho this might be right forHealthy University of Pennsylvania 29
Not applicableUnknownNCT00825045What this trial is testingDopamine D2 and D3 Receptor Occupancy and Clinical Response in Older Patients With SchizophreniaWho this might be right forSchizophreniaSchizoaffective DisorderSchizophreniform Disorder Centre for Addiction and Mental Health 14
Early research (Phase 1)Ended earlyNCT03059563What this trial is testingDopamine D2/D3 Receptor Upregulation by Varenicline in Methamphetamine UsersWho this might be right forDopamine D2/3 Receptor AvailabilityCognitive FunctionMethamphetamine Abuse University of California, Los Angeles 62
Not applicableLooking for participantsNCT03537794What this trial is testingCharacterizing Dopamine Receptor Binding in Treatment Resistant DepressionWho this might be right forTreatment Resistant Depression Unity Health Toronto 45
Testing effectiveness (Phase 2)Study completedNCT01699828What this trial is testingExploring Occupancy of Dopamine D3 Receptor by Buspirone in Humans Using PETWho this might be right forSmoking CessationTobacco Use Cessation Centre for Addiction and Mental Health 6
Testing effectiveness (Phase 2)Active Not RecruitingNCT02815917What this trial is testingEvaluation of D3 Receptor Occupancy Using FLUORTRIOPRIDE ([18F]FTP) PET/CTWho this might be right forD3 Dopamine ReceptorCocaine-dependentHealthy Volunteer University of Pennsylvania 30
Not applicableStudy completedNCT01984177What this trial is testingEffects of Corticorelin Administration on Dopamine Transmission, Craving, and Mood in Cocaine DependenceWho this might be right forCocaine-Related DisordersCocaine AddictionSubstance-Related Disorders Centre for Addiction and Mental Health 17
Testing effectiveness (Phase 2)Study completedNCT03544229What this trial is testingEvaluate the Efficacy and Safety of TAK-906 in Adult Participants With Symptomatic Idiopathic or Diabetic GastroparesisWho this might be right forDiabetic GastroparesisIdiopathic Gastroparesis Millennium Pharmaceuticals, Inc. 242
Early research (Phase 1)Study completedNCT00814957What this trial is testingAn Open Label Positron Emission Tomography (PET) Study of GSK618334 in Healthy Male Subjects Using 11C-PHNO as PET LigandWho this might be right forSubstance Dependence GlaxoSmithKline 12
Early research (Phase 1)Study completedNCT00468806What this trial is testingStudy of Safety, Blood Levels and Brain Receptor Occupancy of GSK598809 Using PET Imaging in Health Males.Who this might be right forHealthy Subjects GlaxoSmithKline 25
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07626034What this trial is testingA Positron Emission Tomography (PET) Study to Evaluate Dopamine D2 and D3 Receptor Occupancy by SIPI6398Who this might be right forSchizophrenia Disorder Shanghai Zhongze Therapeutics Co., Ltd. 9
Early research (Phase 1)Study completedNCT06261905What this trial is testingVitamin D in OUD: Exploration of Alterations on the Dopamine D2/D3 Receptor SystemWho this might be right forOpioid Use Disorder Yale University 5
Not applicableStudy completedNCT03037060What this trial is testingExploring Regulation and Function of Dopamine D3 Receptors in Alcohol Use Disorders: A [11C]-(+)-PHNO StudyWho this might be right forAlcohol Use Disorder Centre for Addiction and Mental Health 17
Early research (Phase 1)Study completedNCT00471588What this trial is testingCharacterize The Modulatory Effects Of Dopamine D2/D3 Receptor Agonist And Antagonist Drugs On Compulsive BehaviorsWho this might be right forObsessive-Compulsive Disorder GlaxoSmithKline 52
Not applicableStudy completedNCT00001320What this trial is testingNeuroimaging of Dopamine Metabolism in Normal and Psychiatric PatientsWho this might be right forHealthySchizophrenia National Institute of Mental Health (NIMH) 265
Early research (Phase 1)Study completedNCT06300580What this trial is testingStudy of Oral ABBV-932 Capsules to Evaluate Dopamine D2 and D3 Receptor Occupancy in Brain in Adult Healthy VolunteersWho this might be right forHealthy Volunteers AbbVie 11
Post-approval studies (Phase 4)WithdrawnNCT05060549What this trial is testingDopamine D3 Receptor Occupancy in Bipolar DepressionWho this might be right forBipolar Depression New York State Psychiatric Institute