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Results for “DNA Damage Repair Deficiency”

391 trials

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Showing 20 of 391 results

Very early researchStudy completedNCT00965666
What this trial is testing

Pilot Study of Etanercept (Enbrel) in Children With Fanconi Anemia

Who this might be right for
Fanconi Anemia
Children's Hospital Medical Center, Cincinnati 3
Not applicableAvailableNCT06731036
What this trial is testing

Expanded Access to CD34+ Selection Utilizing Miltenyi CliniMACS Prodigy® for Patients Receiving Peripheral Blood Stem Cell Transplantations and Stem Cell Boosts

Who this might be right for
Severe Combined ImmunodeficiencyFanconi AnemiaDyskeratosis Congenita+1 more
University of Florida
Not applicableStudy completedNCT00609505
What this trial is testing

Telemedicine vs. Face-to-Face Cancer Genetic Counseling

Who this might be right for
Hereditary Breast and Ovarian Cancer SyndromeLynch Syndrome
Duke University 130
Not applicableLooking for participantsNCT04367246
What this trial is testing

Li-Fraumeni Syndrome/TP53 Biobank

Who this might be right for
Li-Fraumeni SyndromeLi-Fraumeni-Like Syndrome
Abramson Cancer Center at Penn Medicine 300
Not applicableActive Not RecruitingNCT04261972
What this trial is testing

Cell-free DNA in Hereditary And High-Risk Malignancies 1

Who this might be right for
Hereditary Cancer Syndrome
University Health Network, Toronto 1,416
Testing effectiveness (Phase 2)Enrolling By InvitationNCT01852370
What this trial is testing

Sequential Cadaveric Lung and Bone Marrow Transplant for Immune Deficiency Diseases

Who this might be right for
Severe Combined Immunodeficiency (SCID)Immunodeficiency With Predominant T-cell Defect, UnspecifiedSevere Chronic Neutropenia+6 more
Paul Szabolcs 16
Not applicableStudy completedNCT00595127
What this trial is testing

Hematopoietic Stem Cell Transplantation for Treatment of Patients With Fanconi Anemia Lacking a Genotypically Identical Donor, Using Total Body Irradiation, Cyclophosphamide and Fludarabine

Who this might be right for
Fanconi Anemia
Memorial Sloan Kettering Cancer Center 21
Not applicableLooking for participantsNCT07194551
What this trial is testing

Assessing Uterine Cancer Risk in Lynch Syndrome Carriers Using Vaginal Self-sampling and a Health Questionnaire

Who this might be right for
Endometrial CancerLynch Syndrome
University of British Columbia 30
Not applicableLooking for participantsNCT06898996
What this trial is testing

FITting Non-invasive Tests in Lynch Syndrome Surveillance

Who this might be right for
Colorectal Cancer
University of Chicago 400
Not applicableStudy completedNCT00499070
What this trial is testing

Assessing Immune Function in Young Patients With Cytopenia That Did Not Respond to Treatment

Who this might be right for
Dyskeratosis CongenitaFanconi AnemiaMyelodysplastic Syndromes+2 more
University Hospital Freiburg 119
Not applicableStudy completedNCT00856388
What this trial is testing

Fludarabine Phosphate, Melphalan, Total-Body Irradiation, Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer or Bone Marrow Failure Disorders

Who this might be right for
Accelerated Phase Chronic Myelogenous LeukemiaAcute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic SyndromeAdult Acute Lymphoblastic Leukemia in Remission+97 more
Roswell Park Cancer Institute 62
Testing effectiveness (Phase 2)Study completedNCT01142154
What this trial is testing

Pharmacokinetics and Safety Study of Single and Multiple Oral Doses Prodarsan™ in Patients With Cockayne Syndrome

Who this might be right for
Cockayne Syndrome
DNage B.V. 5
Testing effectiveness (Phase 2)Study completedNCT04740190
What this trial is testing

Talazoparib - Carboplatin for Recurrent High-grade Glioma With DDRd

Who this might be right for
Recurrent GliomaRecurrent GlioblastomaPoly ADP Ribose Polymerase (PARP) Inhibitor+2 more
The University of Hong Kong 33
Not applicableEnded earlyNCT03044210
What this trial is testing

Metabolic Study of Cockayne Syndrome

Who this might be right for
Cockayne Syndrome
University Hospital, Strasbourg, France 25
Not applicableEnded earlyNCT00006054
What this trial is testing

Allogeneic Bone Marrow Transplantation in Patients With Primary Immunodeficiencies

Who this might be right for
Immunologic Deficiency SyndromesChediak-Higashi SyndromeCommon Variable Immunodeficiency+11 more
Fairview University Medical Center
Testing effectiveness (Phase 2)Ended earlyNCT03733249
What this trial is testing

Long Term Follow-up Study for Patients Enrolled on the BP-004 Clinical Study

Who this might be right for
Acute Lymphoblastic LeukemiaLeukemia, Acute Myeloid (AML), ChildLymphoma, Non-Hodgkin+9 more
Bellicum Pharmaceuticals 187
Testing effectiveness (Phase 2)Study completedNCT03127215
What this trial is testing

Study of Olaparib/Trabectedin vs. Doctor's Choice in Solid Tumors

Who this might be right for
Cancers With DNA Repair-Deficiency
National Center for Tumor Diseases, Heidelberg 102
Early research (Phase 1)Ended earlyNCT00586274
What this trial is testing

Use of Rft5-Dga to Deplete Alloreactive Cells for Pts With Fanconi Anemia After Haploidentical SCT

Who this might be right for
FANCONI ANEMIA
Baylor College of Medicine 1
Not applicableStudy completedNCT00899522
What this trial is testing

Tissue Sample Collection From Patients With Fanconi Anemia

Who this might be right for
Fanconi AnemiaUnspecified Adult Solid Tumor, Protocol SpecificUnspecified Childhood Solid Tumor, Protocol Specific
OHSU Knight Cancer Institute 8
Not applicableStudy completedNCT01582841
What this trial is testing

Integrating Genetic Testing for Lynch Syndrome in a Managed Care Setting

Who this might be right for
Colon CancerLynch Syndrome
Kaiser Permanente 247
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