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Results for “DNA Repair Gene Mutation”

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Showing 20 of 0 results

Testing effectiveness (Phase 2)Looking for participantsNCT05222971
What this trial is testing

Olaparib With or Without Durvalumab for DDR Gene Mutated Biliary Tract Cancer Following Platinum-based Chemotherapy

Who this might be right for
Biliary Tract CancerDNA Damage Repair Deficiency
Asan Medical Center 62
Not applicableUnknownNCT03294343
What this trial is testing

Risk-Reducing Surgeries for Hereditary Ovarian Cancer

Who this might be right for
Hereditary Breast and Ovarian Cancer SyndromeColorectal Neoplasms, Hereditary NonpolyposisOvariectomy+1 more
Lei Li 600
Testing effectiveness (Phase 2)Active Not RecruitingNCT05933265
What this trial is testing

Study of LP-184 in Patients With Advanced Solid Tumors

Who this might be right for
Advanced Solid TumorMetastatic Solid TumorGBM+4 more
Lantern Pharma Inc. 64
Not applicableStudy completedNCT03889171
What this trial is testing

Comparison to Psychological, Medical and Emotional Influencing Communication and Achievement Factors to Oncogenetics Tests

Who this might be right for
CancerColorectal CancerBreast Cancer+1 more
University Hospital, Montpellier 200
Not applicableLooking for participantsNCT07436312
What this trial is testing

Impact of Consumption of Ultra-processed Foods in Individuals at High Risk of Cancer

Who this might be right for
Breast CancerPancreas CancerColon Cancer+3 more
Gustave Roussy, Cancer Campus, Grand Paris 170
Not applicableUnknownNCT04516083
What this trial is testing

Lynch Syndrome Can be Diagnosed Just From Somatic Mismatch Repair Mutation

Who this might be right for
Cancer Gene MutationLynch SyndromeEndometrial Cancer+1 more
RWJ Barnabas Health at Jersey City Medical Center 100
Testing effectiveness (Phase 2)Ended earlyNCT03631641
What this trial is testing

Nivolumab in Preventing Colon Adenomas in Participants With Lynch Syndrome and a History of Partial Colectomy

Who this might be right for
Colon AdenomaColon CarcinomaLynch Syndrome+2 more
John Hays 3
Not applicableLooking for participantsNCT07220239
What this trial is testing

Menstrual Cup for Early Endometrial Cancer Detection in Lynch Syndrome

Who this might be right for
Endometrial CancerLynch SyndromeScreening+1 more
Jessica D. St. Laurent, MD 25
Testing effectiveness (Phase 2)Looking for participantsNCT03786796
What this trial is testing

Study of Olaparib in Metastatic Renal Cell Carcinoma Patients With DNA Repair Gene Mutations

Who this might be right for
Renal Cell CarcinomaMetastatic Renal Cell CarcinomaKidney Cancer+2 more
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 20
Not applicableUnknownNCT01447199
What this trial is testing

The Molecular Predisposition to Hereditary Nonpolyposis Colon Cancer (HNPCC)

Who this might be right for
Bladder CancerColorectal CancerEndometrial Cancer+3 more
M.D. Anderson Cancer Center 2,000
Early research (Phase 1)UnknownNCT02950064
What this trial is testing

Determine the Safety of BTP-114 for Treatment in Patients With Advanced Solid Tumors With BRCA Mutations

Who this might be right for
Pancreatic NeoplasmsOvarian NeoplasmsBreast Neoplasms+1 more
Placon Therapeutics 95
Testing effectiveness (Phase 2)Active Not RecruitingNCT05203445
What this trial is testing

Olaparib and Pembrolizumab in People With Triple Negative Breast Cancer (TNBC) or Hormone Receptor-positive HER2-negative Breast Cancer

Who this might be right for
Breast Cancer
Memorial Sloan Kettering Cancer Center 6
Not applicableActive Not RecruitingNCT05692596
What this trial is testing

The Pancreas Interception Center (PIC) for Early Detection, Prevention, and Novel Therapeutics

Who this might be right for
Pancreatic Ductal AdenocarcinomaPancreatic CystChronic Pancreatitis+10 more
H. Lee Moffitt Cancer Center and Research Institute 317
Not applicableStudy completedNCT00353639
What this trial is testing

Telomere Repair Gene Mutation in Inflammatory Bowel Disease

Who this might be right for
Inflammatory Bowel Disease
National Heart, Lung, and Blood Institute (NHLBI) 95
Not applicableUnknownNCT02053805
What this trial is testing

Prostate Cancer Screening Among Men With High Risk Genetic Predisposition

Who this might be right for
BRCA1 SyndromeBRCA2 SyndromeLynch Syndrome
Rabin Medical Center 200
Large-scale testing (Phase 3)Study completedNCT01464086
What this trial is testing

LIFSCREEN : Evaluation of Whole Body MRI for Early Detection of Cancers in Subjects With P53 Mutation (Li-Fraumeni Syndrome)

Who this might be right for
Li Fraumeni Syndrome
Gustave Roussy, Cancer Campus, Grand Paris 107
Not applicableLooking for participantsNCT04095195
What this trial is testing

Registry of Subjects at Risk of Pancreatic Cancer

Who this might be right for
Familial Pancreatic CancerBRCA1 MutationBRCA2 Mutation+4 more
Associazione Italiana per lo Studio del Pancreas 1,000
Not applicableActive Not RecruitingNCT02194387
What this trial is testing

Energy Balance Interventions in Increasing Physical Activity in Breast Cancer Gene Positive Patients, Lynch Syndrome-Positive Patients, CLL Survivors or High-Risk Family Members

Who this might be right for
Body Mass Index 25 or GreaterBRCA1 Gene MutationBRCA2 Gene Mutation+8 more
M.D. Anderson Cancer Center 337
Not applicableLooking for participantsNCT06712095
What this trial is testing

Video Capsule Examination in Patients With Lynch Syndrome

Who this might be right for
Lynch SyndromeLi Fraumeni SyndromePTEN Hamartoma Syndrome+7 more
Royal Marsden NHS Foundation Trust 25
Testing effectiveness (Phase 2)Looking for participantsNCT05071222
What this trial is testing

Safety and Efficacy Study of Transplantation of Autologous CD34+ Cells Transduced With the G2ARTE Lentiviral Vector Expressing the DCLRE1C cDNA in Artemis (DCLRE1C) Deficient Severe Combined Immunodeficiency Patients (ARTEGENE)

Who this might be right for
Artemis (DCLRE1C ) Deficient Severe Combined Immunodeficiency
Assistance Publique - Hôpitaux de Paris 7
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